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Academic Journal

Cuminaldehyde and Tobramycin Forestall the Biofilm Threats of Staphylococcus aureus: A Combinatorial Strategy to Evade the Biofilm Challenges.

  • Authors : Roy R; Microbial Ecology Research Laboratory, Department of Biotechnology, The Neotia University, Sarisha, West Bengal, 743368, India.; Paul P

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Biofilms*/Biofilms*/Biofilms*/growth & development ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology

  • Source: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2024 Nov; Vol. 196 (11), pp. 7588-7613. Date of Electronic Publication: 2024 Mar 25.Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A sensitive tobramycin electrochemical aptasensor based on multiple signal amplification cascades.

  • Authors : Zhao Y; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.; Chen Q

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/analysis ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/chemistry ; Biosensing Techniques*/Biosensing Techniques*/Biosensing Techniques*/methods

  • Source: Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2024 Dec; Vol. 160, pp. 108797. Date of Electronic Publication: 2024 Aug 15.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100953583 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms.

  • Authors : Yildirim T; HIPS - Helmholtz Institute for Pharmaceutical Research Saarland, 66123, Saarbrücken, Germany.; Bali A

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/physiology ; Biofilms*/Biofilms*/Biofilms*/drug effects

  • Source: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Oct; Vol. 20 (40), pp. e2401926. Date of Electronic Publication: 2024 Jun 03.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101235338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-6829

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Academic Journal

Dual tobramycin and docosahexaenoic acid loaded nanoemulsions combating Pseudomonas aeruginosa-induced pulmonary infection.

  • Authors : Sun Y; School of Pharmaceutical Sciences, Sun Yat-Sen University, University Town, Guangzhou 510006, PR China.; Lu T

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/chemistry

  • Source: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2024 Oct; Vol. 242, pp. 114088. Date of Electronic Publication: 2024 Jul 11.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synergistic effect of the combination of phenolic compounds and tobramycin on the inhibition of Pseudomonas aeruginosa biofilm.

  • Authors : Lima EMF; Food Research Center (FoRC), Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil.; Bueris V

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Biofilms*/Biofilms*/Biofilms*/growth & development ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects

  • Source: Microbial pathogenesis [Microb Pathog] 2024 Dec; Vol. 197, pp. 107079. Date of Electronic Publication: 2024 Oct 23.Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tobramycin-resistant small colony variant mutant of Salmonella enterica serovar Typhimurium shows collateral sensitivity to nitrofurantoin.

  • Authors : Wang CZ; Guangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.

Subjects: Nitrofurantoin*/Nitrofurantoin*/Nitrofurantoin*/pharmacology ; Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/drug effects ; Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/genetics

  • Source: Virulence [Virulence] 2024 Dec; Vol. 15 (1), pp. 2356692. Date of Electronic Publication: 2024 May 26.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nlmixr2 Versus NONMEM: An Evaluation of Maximum A Posteriori Bayesian Estimates Following External Evaluation of Gentamicin and Tobramycin Population Pharmacokinetic Models.

  • Authors : Duong A; Laboratoire de Suivi Thérapeutique Pharmacologique et Pharmacocinétique, Montréal, QC, Canada.; Faculté de Pharmacie, Université de Montréal, Montréal, QC, Canada.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacokinetics ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/blood

  • Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Jul; Vol. 13 (7), pp. 739-747. Date of Electronic Publication: 2024 Mar 11.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Similar Efficacy and Lower Cost Associated With Ceftazidime Compared to Tobramycin Coupled With Vancomycin in Antibiotic Spacers in the Treatment of Periprosthetic Joint Infection.

  • Authors : Lewis DC; Department of Orthopaedic Surgery, University of Utah, Salt Lake City, Utah.; Blackburn BE

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/economics ; Vancomycin*/Vancomycin*/Vancomycin*/economics

  • Source: The Journal of arthroplasty [J Arthroplasty] 2024 Aug; Vol. 39 (8S1), pp. S323-S327. Date of Electronic Publication: 2024 Apr 16.Publisher: Taylor and Francis Country of Publication: United States NLM ID: 8703515 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hybrids of 3-Hydroxypyridin-4(1 H )-ones and Long-Chain 4-Aminoquinolines as Potent Biofilm Inhibitors of Pseudomonas aeruginosa Potentiate Tobramycin and Polymyxin B Activity.

  • Authors : Miao ZY; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), College of Pharmacy, Jinan University, #855 Xingye Avenue, Guangzhou 511400, China.; Zhang XY

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Biofilms*/Biofilms*/Biofilms*/drug effects ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16835-16857. Date of Electronic Publication: 2024 Sep 17.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Dual-sensitized heterojunction Ag 2 S/ZnS/NiS composites with entire visible-light region absorption for ultrasensitive photoelectrochemical detection of tobramycin.

  • Authors : Jin Y; Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address: .; Yu W

Subjects: Biosensing Techniques* ; Tobramycin*/Tobramycin*/Tobramycin*/analysis ; Tobramycin*/Tobramycin*/Tobramycin*/chemistry

  • Source: Biosensors & bioelectronics [Biosens Bioelectron] 2024 Sep 15; Vol. 260, pp. 116459. Date of Electronic Publication: 2024 Jun 01.Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Does Local Aqueous Tobramycin Injection Reduce Open Fracture-Related Infection Rates?

  • Authors : Southall WGS; Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Lexington, KY; and.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Fractures, Open*/Fractures, Open*/Fractures, Open*/surgery ; Fractures, Open*/Fractures, Open*/Fractures, Open*/complications

  • Source: Journal of orthopaedic trauma [J Orthop Trauma] 2024 Sep 01; Vol. 38 (9), pp. 497-503.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8807705 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Electrochemical aptamer sensor based on AgNPs@PDANSs and "sandwich" structure guidance for the detection of tobramycin in water samples.

  • Authors : Zhao K; School of Environmental Engineering, Henan University of Technology, Lianhua Road 100#, Zhengzhou, 450001, Henan Province, People's Republic of China. .; Ma X

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/analysis ; Tobramycin*/Tobramycin*/Tobramycin*/chemistry ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/chemistry

  • Source: Analytical methods : advancing methods and applications [Anal Methods] 2024 Aug 22; Vol. 16 (33), pp. 5665-5675. Date of Electronic Publication: 2024 Aug 22.Publisher: RSC Pub Country of Publication: England NLM ID: 101519733 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-9679

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Academic Journal

Targeted treatment for biofilm-based infections using PEGylated tobramycin.

  • Authors : Ding L; Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX 78712, USA.; Wang G

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use

  • Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Aug; Vol. 372, pp. 43-58. Date of Electronic Publication: 2024 Jun 14.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet

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Editorial & Opinion

Topical use of tobramycin: A possible innovative treatment of severe skin chronic ulcers.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/administration & dosage

  • Source: Experimental dermatology [Exp Dermatol] 2024 Jul; Vol. 33 (7), pp. e15131.Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9301549 Publication Model: Print Cited Medium: Internet ISSN: 1600-0625

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Academic Journal

Inhalable tobramycin EEG powder formulation for treating Pseudomonas aeruginosa-induced lung infection.

  • Authors : Pangeni R; Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA.; Poudel S

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/microbiology

  • Source: International journal of pharmaceutics [Int J Pharm] 2024 Sep 05; Vol. 662, pp. 124504. Date of Electronic Publication: 2024 Jul 24.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The uncharacterized PA3040-3042 operon is part of the cell envelope stress response and a tobramycin resistance determinant in a clinical isolate of Pseudomonas aeruginosa .

  • Authors : Østergaard MZ; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Nielsen FD

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/virology

  • Source: Microbiology spectrum [Microbiol Spectr] 2024 Aug 06; Vol. 12 (8), pp. e0387523. Date of Electronic Publication: 2024 Jul 01.Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of Vancomycin/Tobramycin-Doped Ceramic Composite (Polyvinyl Alcohol Composite-Vancomycin/Tobramycin-Polymeric Dicalcium Phosphate Dihydrate) in a Rat Femur Model Implanted With Contaminated Porous Titanium Cylinders.

  • Authors : Aboona F; Section of Orthopaedic Surgery, Ascension-Providence Hospital, Southfield, Michigan.; Bou-Akl T

Subjects: Rats, Sprague-Dawley* ; Vancomycin*/Vancomycin*/Vancomycin*/administration & dosage ; Titanium*

  • Source: The Journal of arthroplasty [J Arthroplasty] 2024 Aug; Vol. 39 (8S1), pp. S310-S316. Date of Electronic Publication: 2024 May 06.Publisher: Taylor and Francis Country of Publication: United States NLM ID: 8703515 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Necessity of Tobramycin trough Levels in Once Daily Iv-Treatment in Patients with Cystic Fibrosis.

  • Authors : Schlegtendal A; Department of pediatrics, Ruhr-Universität Bochum Medizinische Fakultät, Bochum, Germany.; Rettberg S

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/complications ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage

  • Source: Klinische Padiatrie [Klin Padiatr] 2024 Feb; Vol. 236 (2), pp. 116-122. Date of Electronic Publication: 2024 Jan 29.Publisher: Ferdinand Enke Verlag Country of Publication: Germany NLM ID: 0326144 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Development of a tobramycin-loaded calcium alginate microsphere/chitosan composite sponge with antibacterial effects as a wound dressing.

  • Authors : Ma R; College of Stomatology, Ningxia Medical University, Yinchuan 750004, People's Republic of China.; Department of Stomatology, The Third People's Hospital of Yinchuan, Yinchuan 750004, People's Republic of China.

Subjects: Alginates*/Alginates*/Alginates*/chemistry ; Chitosan*/Chitosan*/Chitosan*/chemistry ; Microspheres*

  • Source: Biomedical materials (Bristol, England) [Biomed Mater] 2024 Jun 14; Vol. 19 (4). Date of Electronic Publication: 2024 Jun 14.Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Impact of pH modification of the empirically used tobramycin ophthalmic solution on MIC90 concentration in tears and aqueous humor of donkeys (Equus asinus).

  • Authors : Ibrahim A; Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt. .; Abd-Elrasoul MAA

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacokinetics

  • Source: BMC veterinary research [BMC Vet Res] 2024 May 23; Vol. 20 (1), pp. 218. Date of Electronic Publication: 2024 May 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148

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Academic Journal

Is there a multinational consensus of tobramycin prescribing and monitoring for cystic fibrosis? Survey of current therapeutic drug monitoring practices in USA/Canada, UK/Ireland, and Australia/New Zealand.

  • Authors : Larcombe R; University of South Australia, Adelaide, South Australia, Australia .; Flinders Medical Centre, Bedford Park, South Australia, Australia.

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/blood

  • Source: European journal of hospital pharmacy : science and practice [Eur J Hosp Pharm] 2024 Jun 21; Vol. 31 (4), pp. 301-306. Date of Electronic Publication: 2024 Jun 21.Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101578294 Publication Model: Electronic Cited Medium: Print ISSN:

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Academic Journal

Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model evaluated by mechanism-based modelling and whole genome sequencing.

  • Authors : Breen SKJ; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Harper M

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Aztreonam*/Aztreonam*/Aztreonam*/pharmacology

  • Source: International journal of antimicrobial agents [Int J Antimicrob Agents] 2024 Jun; Vol. 63 (6), pp. 107161. Date of Electronic Publication: 2024 Mar 30.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Tobramycin-mediated self-assembly of DNA nanostructures for targeted treatment of Pseudomonas aeruginosa -infected lung inflammation.

  • Authors : Xu Y; Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China. .; Liu Q

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage

  • Source: Biomaterials science [Biomater Sci] 2024 Apr 30; Vol. 12 (9), pp. 2331-2340. Date of Electronic Publication: 2024 Apr 30.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Membrane fluidity homeostasis is required for tobramycin-enhanced biofilm in Pseudomonas aeruginosa .

  • Authors : David A; Unité de recherche Communication Bactérienne et Stratégies Anti-infectieuses, CBSA UR4312, Université de Rouen Normandie, Normandie Université, Evreux, France.; Fédération de Recherche Normande Sécurité Sanitaire, bien être, Aliment Durable (SéSAD), Evreux, France.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy; Humans

  • Source: Microbiology spectrum [Microbiol Spectr] 2024 Apr 02; Vol. 12 (4), pp. e0230323. Date of Electronic Publication: 2024 Feb 27.Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Efficacy of adjunctive inhaled colistin and tobramycin for ventilator-associated pneumonia: systematic review and meta-analysis.

  • Authors : Buendía JA; Research Group in Pharmacology and Toxicology, Department of Pharmacology and Toxicology, University of Antioquia, Medellín, Colombia. .; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK. .

Subjects: Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/drug therapy ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage ; Colistin*/Colistin*/Colistin*/administration & dosage

  • Source: BMC pulmonary medicine [BMC Pulm Med] 2024 May 02; Vol. 24 (1), pp. 213. Date of Electronic Publication: 2024 May 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100968563 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2466

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Academic Journal

Tobramycin Systemic Absorption in Lung Transplant Recipients Treated With Inhaled Tobramycin: A Cohort Study.

  • Authors : Sempere A; Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Los-Arcos I

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/chemically induced ; Tobramycin*/Tobramycin*/Tobramycin*/adverse effects; Humans

  • Source: Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2024 Mar 28; Vol. 37, pp. 12579. Date of Electronic Publication: 2024 Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 8908516 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Assessment of inhaled cationic antibiotics in an in vitro model of Pseudomonas aeruginosa lung biofilm.

  • Authors : Awad R; Université de Poitiers, PHAR2, Inserm U1070, Poitiers, France.; Marchand S

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/physiology ; Biofilms*/Biofilms*/Biofilms*/drug effects

  • Source: Microbial pathogenesis [Microb Pathog] 2024 Dec; Vol. 197, pp. 107020. Date of Electronic Publication: 2024 Oct 15.Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The point mutation A1387G in the 16S rRNA gene confers aminoglycoside resistance in Campylobacter jejuni and Campylobacter coli .

  • Authors : Zarske M; German Federal Institute for Risk Assessment (BfR), Department of Biological Safety, National Reference Laboratory for Campylobacter, Berlin, Germany.; Werckenthin C

Subjects: Campylobacter coli*/Campylobacter coli*/Campylobacter coli*/genetics ; Campylobacter coli*/Campylobacter coli*/Campylobacter coli*/drug effects ; Campylobacter jejuni*/Campylobacter jejuni*/Campylobacter jejuni*/genetics

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Nov 06; Vol. 68 (11), pp. e0083324. Date of Electronic Publication: 2024 Oct 15.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Antimicrobial and antibiotic-potentiating effect of calcium peroxide nanoparticles on oral bacterial biofilms.

  • Authors : Bankar N; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, 66123, Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123, Saarbrücken, Germany.

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Biofilms*/Biofilms*/Biofilms*/growth & development ; Nanoparticles*/Nanoparticles*/Nanoparticles*/chemistry

  • Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2024 Oct 15; Vol. 10 (1), pp. 106. Date of Electronic Publication: 2024 Oct 15.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design and application of an ultrasensitive and selective tobromycin electrochemiluminescence aptasensor using MXene /Ni/Sm-LDH-based nanocomposite.

  • Authors : Nasri F; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, 1439817435, Iran.

Subjects: Nanocomposites*/Nanocomposites*/Nanocomposites*/chemistry ; Electrochemical Techniques*/Electrochemical Techniques*/Electrochemical Techniques*/methods ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/chemistry

  • Source: Mikrochimica acta [Mikrochim Acta] 2024 Aug 04; Vol. 191 (9), pp. 506. Date of Electronic Publication: 2024 Aug 04.Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 7808782 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-5073

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Academic Journal

Tobramycin a Priori Dosing Regimens Based on PopPK Model Simulations in Critically Ill Patients: Are They Transferable?

  • Authors : Duong A; Faculté de Pharmacie, Université de Montréal, Montréal.; Laboratoire de Suivi Thérapeutique Pharmacologique et Pharmacocinétique, Faculté de Pharmacie, Université de Montréal, Montréal.

Subjects: Tobramycin* ; Critical Illness*; Humans

  • Source: Therapeutic drug monitoring [Ther Drug Monit] 2023 Oct 01; Vol. 45 (5), pp. 616-622. Date of Electronic Publication: 2023 Mar 07.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

In Vivo Intra-Articular Antibiotic Concentrations at 24 Hours After TKA Fall Below the Minimum Inhibitory Concentration for Most Bacteria: A Randomized Study of Commercially Available Bone Cement.

Subjects: Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/adverse effects ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/administration & dosage ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacokinetics

  • Source: The Journal of bone and joint surgery. American volume [J Bone Joint Surg Am] 2024 Sep 18; Vol. 106 (18), pp. 1664-1672. Date of Electronic Publication: 2024 Jul 25.Publisher: Journal of Bone and Joint Surgery Country of Publication: United States NLM ID: 0014030 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Does Sample Size, Sampling Strategy, or Handling of Concentrations Below the Lower Limit of Quantification Matter When Externally Evaluating Population Pharmacokinetic Models?

  • Authors : El Hassani M; Faculté de pharmacie, Université de Montréal, 2940 chemin de Polytechnique, Montréal, QC, H3T 1J4, Canada. .; Laboratoire de suivi thérapeutique pharmacologique et pharmacocinétique, Faculté de pharmacie, Université de Montréal, Montreal, QC, Canada. .

Subjects: Vancomycin*/Vancomycin*/Vancomycin*/pharmacokinetics ; Vancomycin*/Vancomycin*/Vancomycin*/administration & dosage ; Models, Biological*

  • Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Jul; Vol. 49 (4), pp. 419-436. Date of Electronic Publication: 2024 May 05.Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Redox-responsive degradation of antimicrobials with programmable drug release for enhanced antibacterial activity.

  • Authors : Zhang Y; Department of Pharmacology, Nanomedicine Engineering Laboratory of Jilin Province, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.; Yang X

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemistry ; Oxidation-Reduction*

  • Source: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2025 Jan; Vol. 245, pp. 114308. Date of Electronic Publication: 2024 Oct 09.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dual fluorescence-colorimetric sensor based on silver nanoparticles for determination of tobramycin in its pharmaceutical preparations.

  • Authors : Abdel Hamid M; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.; Habib A

Subjects: Tobramycin* ; Metal Nanoparticles*; Colorimetry/Colorimetry/Colorimetry/methods

  • Source: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2023 Dec 15; Vol. 303, pp. 123172. Date of Electronic Publication: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557

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Academic Journal

A prospective phase IIA multicenter double-blinded randomized placebo-controlled clinical trial evaluating the efficacy and safety of inhaled Tobramycin in patients with ventilator-associated pneumonia (iToVAP).

  • Authors : Angermair S; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Berlin, Germany. Electronic address: .; Deja M

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/adverse effects ; Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/drug therapy ; Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/Pneumonia, Ventilator-Associated*/microbiology

  • Source: Anaesthesia, critical care & pain medicine [Anaesth Crit Care Pain Med] 2023 Oct; Vol. 42 (5), pp. 101249. Date of Electronic Publication: 2023 May 20.Publisher: Published by Elsevier Masson SAS on behalf of the Société française d'anesthésie et de réanimation (Sfar) Country of Publication: France NLM ID:

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Academic Journal

Development of a novel tobramycin dependent riboswitch.

  • Authors : Kraus L; Fachbereich Biologie, TU Darmstadt, Schnittspahnstrasse 10, 64287 Darmstadt, Germany.; Centre for Synthetic Biology, TU Darmstadt, 64287 Darmstadt, Germany.

Subjects: Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/chemistry ; Riboswitch* ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Nov 10; Vol. 51 (20), pp. 11375-11385.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Micromotor-Enabled Active Hydrogen and Tobramycin Delivery for Synergistic Sepsis Therapy.

  • Authors : Song Y; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.; Zhang R

Subjects: Tobramycin* ; Sepsis*/Sepsis*/Sepsis*/drug therapy; Animals

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Nov; Vol. 10 (33), pp. e2303759. Date of Electronic Publication: 2023 Oct 11.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Safety Profile of Seven-Day Intra-articular Antibiotic Irrigation for the Treatment of Chronic Periprosthetic Joint Infection: A Prospective Randomized Phase II Comparative Study.

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/administration & dosage ; Prosthesis-Related Infections*/Prosthesis-Related Infections*/Prosthesis-Related Infections*/drug therapy ; Tobramycin*/Tobramycin*/Tobramycin*/administration & dosage

  • Source: The Journal of arthroplasty [J Arthroplasty] 2024 Sep; Vol. 39 (9S1), pp. S229-S235.e1. Date of Electronic Publication: 2024 Apr 09.Publisher: Taylor and Francis Country of Publication: United States NLM ID: 8703515 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mutations Affecting Cellular Levels of Cobalamin (Vitamin B 12 ) Confer Tolerance to Bactericidal Antibiotics in Burkholderia cenocepacia .

  • Authors : Lee D; Division of Biosystems and Biomedical Sciences, College of Health Sciences, Korea University, Seoul 02841, Republic of Korea.; Park J

Subjects: Vitamin B 12*/Vitamin B 12*/Vitamin B 12*/pharmacology ; Vitamin B 12*/Vitamin B 12*/Vitamin B 12*/metabolism ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

  • Source: Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2024 Aug 28; Vol. 34 (8), pp. 1609-1616. Date of Electronic Publication: 2024 Jul 11.Publisher: Korean Society for Microbiology and Biotechnology Country of Publication: Korea (South) NLM ID: 9431852 Publication Model: Print-Electronic Cited

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Academic Journal

Effect of L-arginine on cystic fibrosis Pseudomonas aeruginosa biofilms.

  • Authors : Eisha S; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.; Morris AJ

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Biofilms*/Biofilms*/Biofilms*/growth & development ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Aug 07; Vol. 68 (8), pp. e0033624. Date of Electronic Publication: 2024 Jul 18.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Effect of biofilm physical characteristics on their susceptibility to antibiotics: impacts of low-frequency ultrasound.

  • Authors : Nahum Y; University of Notre Dame, Department of Civil and Environmental Engineering and Earth Sciences, Notre Dame, IN, USA.; Gross N

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Biofilms*/Biofilms*/Biofilms*/growth & development ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

  • Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2024 Aug 19; Vol. 10 (1), pp. 70. Date of Electronic Publication: 2024 Aug 19.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A sensitive surface-enhanced Raman spectroscopy detection for gentamicin and tobramycin using γ-Al 2 O 3 -modified silver nanoparticles coated with bovine serum albumin as substrate.

  • Authors : Bi S; College of Chemistry, Changchun Normal University, Changchun, 130032, China. Electronic address: .; Yuan Y

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/chemistry ; Metal Nanoparticles*/Metal Nanoparticles*/Metal Nanoparticles*/chemistry

  • Source: Talanta [Talanta] 2023 Aug 01; Vol. 260, pp. 124635. Date of Electronic Publication: 2023 May 05.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Guanidinylated Amphiphilic Tobramycin Derivatives Synergize with β-Lactam/β-Lactamase Inhibitor Combinations against Pseudomonas aeruginosa .

  • Authors : Ramirez DM; Department of Chemistry, University of Manitoba, Winnipeg, MBR3T 2N2, Canada.; Ramirez D

Subjects: Lactams* ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Pseudomonas aeruginosa

  • Source: ACS infectious diseases [ACS Infect Dis] 2023 Sep 08; Vol. 9 (9), pp. 1754-1768. Date of Electronic Publication: 2023 Aug 21.Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity.

  • Authors : Agyeman AA; Centre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; López-Causapé C

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy

  • Source: International journal of antimicrobial agents [Int J Antimicrob Agents] 2023 Sep; Vol. 62 (3), pp. 106887. Date of Electronic Publication: 2023 Jun 12.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Acute Kidney Injury because of Implanted Tobramycin Pellets: A Case Report.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/adverse effects ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacokinetics ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/chemically induced

  • Source: JBJS case connector [JBJS Case Connect] 2023 Apr 06; Vol. 13 (2). Date of Electronic Publication: 2023 Apr 06 (Print Publication: 2023).Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101596828 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Development and Evaluation of a Height-Based Tobramycin Initial Dosing Nomogram for the Treatment of Adult Cystic Fibrosis Pulmonary Exacerbations.

  • Authors : El Hassani M; Faculté de pharmacie, Université de Montréal, Montreal, Canada.; Laboratoire de suivi thérapeutique pharmacologique et pharmacocinétique, Faculté de pharmacie, Université de Montréal, Montreal, Canada.

Subjects: Tobramycin* ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy; Humans

  • Source: Therapeutic drug monitoring [Ther Drug Monit] 2023 Apr 01; Vol. 45 (2), pp. 259-264.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

New Recommendations of a Height-Based Dosing Regimen of Tobramycin for Cystic Fibrosis in Adults: A Population Pharmacokinetic Analysis.

  • Authors : Koloskoff K; Faculty of Pharmacy, Université de Montréal.; Laboratoire STP2, Faculty of Pharmacy, Université de Montréal

Subjects: Tobramycin* ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/complications

  • Source: Therapeutic drug monitoring [Ther Drug Monit] 2023 Apr 01; Vol. 45 (2), pp. 251-258.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Population Pharmacokinetics and AUC-Guided Dosing of Tobramycin in the Treatment of Infections Caused by Glucose-Nonfermenting Gram-Negative Bacteria.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use ; Anti-Bacterial Agents*; Humans

  • Source: Clinical therapeutics [Clin Ther] 2023 May; Vol. 45 (5), pp. 400-414.e2. Date of Electronic Publication: 2023 Apr 27.Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Collateral Sensitivity to Fosfomycin of Tobramycin-Resistant Mutants of Pseudomonas aeruginosa Is Contingent on Bacterial Genomic Background.

  • Authors : Genova R; Centro Nacional de Biotecnología, CSIC, 28043 Madrid, Spain.; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, CSIC, 18008 Granada, Spain.

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Fosfomycin*/Fosfomycin*/Fosfomycin*/pharmacology; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 07; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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