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Efficacy of eculizumab in transplantation-associated thrombotic microangiopathy: results of the French nationwide study on behalf of the SFGM-TC and the CNR-MAT.

• Authors : Peyre M; Hematology Department, Saint-Antoine Hospital, APHP, Paris, France.; Sicre de Fontbrune F

Subjects: Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/therapeutic use ; Thrombotic Microangiopathies*/Thrombotic Microangiopathies*/Thrombotic Microangiopathies*/etiology; Adolescent

• Source: Bone marrow transplantation [Bone Marrow Transplant] 2024 Jul; Vol. 59 (7), pp. 1034-1036. Date of Electronic Publication: 2024 Apr 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Real-life study to assess effectiveness and safety of eculizumab in patients with neuromyelitis optica spectrum disorders in France: protocol for ECUP4, an observational study.

• Authors : Marignier, Romain; Laplaud, David; Zéphir, Hélène

Subjects: NEUROMYELITIS optica; PATIENT safety; FRENCH peopleFRANCE

• Source: Frontiers in Neurology; 2024, p1-8, 8p

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Eculizumab in gemcitabine-induced thrombotic microangiopathy: experience of the French thrombotic microangiopathies reference centre.

• Authors : Grall M; Medical Intensive Care Unit, Rouen University Hospital, 37 boulevard Gambetta, 76031, Rouen Cedex, France.; French TMA Reference Centre, Hopital Saint-Antoine, Sorbonne Université, AP-HP, Paris, France.

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/complications ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/diagnosis ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/therapy

• Source: BMC nephrology [BMC Nephrol] 2021 Jul 21; Vol. 22 (1), pp. 267. Date of Electronic Publication: 2021 Jul 21.Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369

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Outbreak of Escherichia coli O104:H4 haemolytic uraemic syndrome in France: outcome with eculizumab.

• Authors : Delmas, Yahsou; Vendrely, Benoît; Clouzeau, Benjamin

Subjects: HEMOLYTIC-uremic syndrome treatment; ESCHERICHIA coli diseases; ECULIZUMABFRANCE

• Source: Nephrology Dialysis Transplantation; Mar2014, Vol. 29 Issue 3, p565-572, 8p

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Off-label use of the expensive orphan drug eculizumab in France 2009-2013 and the impact of literature: focus on the transplantation field.

• Authors : Castañeda-Sanabria, Johann; Hajage, David; Jouan, Melisande

Subjects: DRUG utilization; DRUG prescribing; MONOCLONAL antibodiesFRANCE

• Source: European Journal of Clinical Pharmacology; Jun2016, Vol. 72 Issue 6, p737-746, 10p, 1 Chart, 2 Graphs

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Researchers at National Center for Scientific Research (CNRS) Report New Data on Complement System Proteins (Eculizumab epitope on complement C5: Progress towards a better understanding of the mechanism of action).

• Source: Health & Medicine Week. 2016, pages. 4102

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Researchers at University Hospital Detail Findings in Escherichia coli (Outbreak of Escherichia coli O104:H4 haemolytic uraemic syndrome in France: outcome with eculizumab).

• Source: Health & Medicine Week. 2015, pages. 4746

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Reports Summarize Antineoplastic Monoclonal Antibodies Study Results from University Hospital (Eculizumab for Treatment of Rapidly Progressive C3 Glomerulopathy).

• Source: Biotech Week. 2015, pages. 749

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Use of Eculizumab in Patients With Allogeneic Stem Cell Transplant-Associated Thrombotic Microangiopathy: A Study From the SFGM-TC.

• Authors : de Fontbrune FS; 1 Hématologie Greffe de Moelle, Hôpital Saint Louis, APHP, Université Paris Diderot, Paris, France. 2 Service d'Hématologie Pédiatrique, Hôpital de la Timone, Marseille, France. 3 Service d'Onco-hematologie Pédiatrique, Hôpital Arnaud de Villeneuve, Centre Hospitalier Universitaire de Montpellier, Montpellier, France. 4 Service d'Hématologie, CHU de Purpan, Toulouse, France. 5 Département de Néphrologie et Transplantation d'organe, CHU de Rangueil, Toulouse, France. 6 Service d'Hématologie, Hôpital de la Pitié Salpetrière, APHP, Université Pierre et Marie Curie, Paris. 7 Service de Thérapie Cellulaire et d'Hématologie Clinique, Hôpital d'Estaing, CHU Clermont Ferrand, Université d'Auvergne, Clermont-Ferrand, France. 8 Service d'Immuno-hématologie et Rhumatologie pédiatrique, Hôpital Necker-Enfants Malades, Laboratoire INSERM U768, Institut Imagine, Université Sorbonne Paris-cité, Paris, France. 9 Centre de Néphrologie et Transplantation Rénale, Hôpital de la Conception, APHM, Université d'Aix Marseille, Marseille, France. 10 Service d'Hématologie, Hôpital Hautepierre, Hôpitaux Universitaire de Strasbourg, Strasbourg, France. 11 Département de Biostatistiques, Hôpital Saint Louis, APHP, Université Paris Diderot, Paris, France. 12 Service d'Immunologie Biologique, Hôpital Européen George Pompidou, APHP, CHU Paris Ouest, Paris, France. 13 Service d'Hématologie Biologique, Hôpital Antoine Beclère, APHP, Université Paris Sud, Clamart, France. 14 Service d'Hématologie, Centre de Référence des Microangiopathies Thrombotiques, Hôpitaux Universitaires de l'Est Parisien, APHP, Université Pierre et Marie Curie, Paris, France.; Galambrun C

Subjects: Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*therapeutic use ; Hematopoietic Stem Cell Transplantation/Hematopoietic Stem Cell Transplantation/Hematopoietic Stem Cell Transplantation/*adverse effects ; Thrombotic Microangiopathies/Thrombotic Microangiopathies/Thrombotic Microangiopathies/*drug therapy

• Source: Transplantation [Transplantation] 2015 Sep; Vol. 99 (9), pp. 1953-9.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print Cited Medium: Internet ISSN:

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Insights from the use in clinical practice of eculizumab in adult patients with atypical hemolytic uremic syndrome affecting the native kidneys: an analysis of 19 cases.

• Authors : Fakhouri F; Department of Nephrology and Immunology, ITUN and INSERM UMR S-1064, CHU de Nantes, Nantes, France. Electronic address: .; Delmas Y

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/pathology ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/physiopathology ; Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/administration & dosage

• Source: American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2014 Jan; Vol. 63 (1), pp. 40-8. Date of Electronic Publication: 2013Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8110075 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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