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Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression.

• Authors : Cellerai C; Laboratory of AIDS Immunopathogenesis, Service of Immunology and Allergy, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.; Perreau M

Subjects: Cell Proliferation* ; Cytotoxicity, Immunologic*; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology

• Source: Journal of virology [J Virol] 2010 Apr; Vol. 84 (8), pp. 3868-78. Date of Electronic Publication: 2010 Feb 03.Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium:

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Summary and comparison of the perforin in teleosts and mammals: A review.

• Authors : Xu, Jiahui (AUTHOR); Yang, Ning (AUTHOR); Xie, Ting (AUTHOR)

Subjects: MAMMALS; OSTEICHTHYES; BIOLOGICAL evolution

• Source: Scandinavian Journal of Immunology. Jul2021, Vol. 94 Issue 1, p1-13. 13p.

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Finding a Balance between Protection and Pathology: The Dual Role of Perforin in Human Disease.

• Authors : Willenbring, Robin C.; Johnson, Aaron J.

Subjects: PATHOLOGY; PERFORINS; CYTOTOXINS

• Source: International Journal of Molecular Sciences; Aug2017, Vol. 18 Issue 8, p1608, 18p

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Researchers' Work from French National Institute of Health and Medical Research (INSERM) Focuses on Antigen-Presenting Cells (Plasmacytoid Dendritic Cells Die by the CD8 T Cell-Dependent Perforin Pathway during Acute Nonviral Inflammation).

• Source: Health & Medicine Week. 2016, pages. 934

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Researchers' Work from French National Institute of Health and Medical Research (INSERM) Focuses on Antigen-Presenting Cells (Plasmacytoid Dendritic Cells Die by the CD8 T Cell-Dependent Perforin Pathway during Acute Nonviral Inflammation)

• Source: Health & Medicine Week. November 11, 2016, 934

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Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential

• Authors : Jo, Juandy^1,2,3; Bengsch, Bertram^1,2,3; Seigel, Bianca^1,2,3

Subjects: *PERFORINS; *HEPATITIS C virus; *CD8 antigen

• Source: Journal of Hepatology. Jul2012, Vol. 57 Issue 1, p9-16. 8p.

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Role of Genetic Polymorphism Present in Macrophage Activation Syndrome Pathway in Post Mortem Biopsies of Patients with COVID-19.

• Authors : Zanchettin, Aline Cristina; Barbosa, Leonardo Vinicius; Dutra, Anderson Azevedo

Subjects: MACROPHAGE activation syndrome; COVID-19; GENETIC polymorphismsTHERMO Fisher Scientific Inc.

• Source: Viruses (1999-4915); Aug2022, Vol. 14 Issue 8, p1699-1699, 13p

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Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells.

• Authors : Taylor, Thyneice R. (AUTHOR); Whalen, Margaret M. (AUTHOR)

Subjects: PHYSIOLOGICAL effects of zinc; MITOGEN-activated protein kinases; IMMUNE response

• Source: Toxicology Mechanisms & Methods. Oct2011, Vol. 21 Issue 8, p577-584. 8p. 7 Graphs.

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Plasmacytoid Dendritic Cells Die by the CD8 T Cell-Dependent Perforin Pathway during Acute Nonviral Inflammation.

• Authors : Mossu, Adrien^1,2,3,4; Daoui, Anna^1,2,3,4; Bonnefoy, Francis^1,2,3,4

Subjects: *DENDRITIC cells; *PERFORINS; *INFLAMMATION

• Source: Journal of Immunology. 9/1/2016, Vol. 197 Issue 5, p1672-1682. 11p.

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Mechanisms of natural killer cell‐mediated cellular cytotoxicity.

• Authors : Prager, Isabel; Watzl, Carsten

Subjects: CELL-mediated cytotoxicity; KILLER cells; PERFORINS

• Source: Journal of Leukocyte Biology; Jun2019, Vol. 105 Issue 6, p1319-1329, 11p

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