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Academic Journal

Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei.

  • Authors : Beaver AK; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Subjects: Antigenic Variation*/Antigenic Variation*/Antigenic Variation*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/immunology

  • Source: Nature [Nature] 2024 Dec; Vol. 636 (8042), pp. 430-437. Date of Electronic Publication: 2024 Oct 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in trypanosomes.

  • Authors : Kieft R; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Zhang Y

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; Protein Phosphatase 1*/Protein Phosphatase 1*/Protein Phosphatase 1*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. 6866-6885.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Poly(m 6 A) tails stabilize transcripts.

  • Authors : Lavergne G; Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015, Lausanne, Switzerland.; Roignant JY

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics; Animals

  • Source: Molecular cell [Mol Cell] 2022 Jun 02; Vol. 82 (11), pp. 1979-1980.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164

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Academic Journal

N 6 -methyladenosine in poly(A) tails stabilize VSG transcripts.

  • Authors : Viegas IJ; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; de Macedo JP

Subjects: RNA Processing, Post-Transcriptional* ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics

  • Source: Nature [Nature] 2022 Apr; Vol. 604 (7905), pp. 362-370. Date of Electronic Publication: 2022 Mar 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes.

  • Authors : Budzak J; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington, London, SW7 2AZ, UK.; Jones R

Subjects: RNA Splicing* ; Transcription, Genetic*; Nuclear Bodies/Nuclear Bodies/Nuclear Bodies/*genetics

  • Source: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 101. Date of Electronic Publication: 2022 Jan 10.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.

  • Authors : Hempelmann A; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany.; Hartleb L

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*drug effects ; Cell Movement/Cell Movement/Cell Movement/*drug effects ; Single-Domain Antibodies/Single-Domain Antibodies/Single-Domain Antibodies/*pharmacology

  • Source: Cell reports [Cell Rep] 2021 Nov 02; Vol. 37 (5), pp. 109923.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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Academic Journal

Dynamic, variable oligomerization and the trafficking of variant surface glycoproteins of Trypanosoma brucei.

  • Authors : Umaer K; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, USA.; Eurofins, Spring House, Pennsylvania, USA.

Subjects: Trypanosoma brucei brucei* ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics; Cell Membrane

  • Source: Traffic (Copenhagen, Denmark) [Traffic] 2021 Aug; Vol. 22 (8), pp. 274-283. Date of Electronic Publication: 2021 Jun 29.Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0854

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Academic Journal

TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei.

  • Authors : Davies C; Sir Alexander Fleming Building, Department of Life Sciences, Imperial College London, South Kensington, London SW7 2AZ, UK.; Ooi CP

Subjects: Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*metabolism ; Repressor Proteins/Repressor Proteins/Repressor Proteins/*metabolism ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Apr 06; Vol. 49 (6), pp. 3242-3262.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes.

  • Authors : Faria J; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, UK.; Luzak V

Subjects: RNA Splicing/RNA Splicing/RNA Splicing/*genetics ; Transcription, Genetic/Transcription, Genetic/Transcription, Genetic/*genetics ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*genetics

  • Source: Nature microbiology [Nat Microbiol] 2021 Mar; Vol. 6 (3), pp. 289-300. Date of Electronic Publication: 2021 Jan 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Telomere and Subtelomere R-loops and Antigenic Variation in Trypanosomes.

  • Authors : Saha A; Center for Gene Regulation in Health and Disease, Department of Biological, Geological, and Environmental Sciences, College of Science and Health Professions, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH 44115, USA.; Nanavaty VP

Subjects: RNA, Transfer/RNA, Transfer/RNA, Transfer/*metabolism ; Telomere/Telomere/Telomere/*metabolism ; Trypanosoma brucei brucei/Trypanosoma brucei brucei/Trypanosoma brucei brucei/*genetics

  • Source: Journal of molecular biology [J Mol Biol] 2020 Jul 10; Vol. 432 (15), pp. 4167-4185. Date of Electronic Publication: 2019 Nov 02.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  441 results for ""Trypanosoma brucei brucei""