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Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases.

• Authors : De Cesare V; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, DD1 5EH, Scotland, United Kingdom.; Carbajo Lopez D

Subjects: Deubiquitinating Enzymes/Deubiquitinating Enzymes/Deubiquitinating Enzymes/*genetics ; Esterases/Esterases/Esterases/*genetics ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*genetics

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 26; Vol. 118 (4).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.

• Authors : Chen IC; Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan.; Chang CN

Subjects: Antioxidants* ; Neuroprotective Agents* ; Phytotherapy*

• Source: The American journal of Chinese medicine [Am J Chin Med] 2019; Vol. 47 (1), pp. 63-95. Date of Electronic Publication: 2019 Jan 07.Publisher: World Scientific Pub Country of Publication: Singapore NLM ID: 7901431 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons.

• Authors : Chen IC; Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan.; Chang KH

Subjects: Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/*pathology ; Isoflavones/Isoflavones/Isoflavones/*pharmacology ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*pathology

• Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2019 Oct 07; Vol. 2019, pp. 8130481. Date of Electronic Publication: 2019 Oct 07 (Print Publication: 2019).Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101479826 Publication Model: eCollection Cited Medium: Internet ISSN:

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Josephin domain-containing proteins from a variety of species are active de-ubiquitination enzymes.

• Authors : Tzvetkov N; Department of Cellular Biochemistry, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.; Breuer P

Subjects: Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

• Source: Biological chemistry [Biol Chem] 2007 Sep; Vol. 388 (9), pp. 973-8.Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 9700112 Publication Model: Print Cited Medium: Print ISSN: 1431-6730 (Print)

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Immunohistochemical study of neuronal intranuclear and cytoplasmic inclusions in Machado–Joseph disease.

• Authors : Hayashi, Masahiro (AUTHOR); Kobayashi, Katsuji (AUTHOR); Furuta, Hisakazu (AUTHOR)

Subjects: FRIEDREICH'S ataxia; MONOCLONAL antibodies; UBIQUITIN

• Source: Psychiatry & Clinical Neurosciences. Apr2003, Vol. 57 Issue 2, p205-213. 9p. 3 Charts.

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Ubiquitin-related network underlain by (CAG)n loci modulate age at onset in Machado-Joseph disease.

• Authors : Zhao Chen; Chunrong Wang; Caifa Zheng

Subjects: UBIQUITIN; SPINOCEREBELLAR ataxia; GENE regulatory networks

• Source: Brain: A Journal of Neurology; Apr2017, Vol. 140 Issue 4, p1-5, 5p

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Evolutionary model of repeat insertions in Ataxin‐3 traces the origin of the polyglutamine stretch to an ancestral ubiquitin binding module.

• Authors : Felício, Daniela; Martins, Sandra; Alves, Guilherme Pimenta

• Source: Protein Science: A Publication of the Protein Society; Dec2024, Vol. 33 Issue 12, p1-12, 12p

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The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy.

• Authors : Herzog, Laura K.¹ (AUTHOR); Kevei, Éva² (AUTHOR); Marchante, Ricardo² (AUTHOR)

Subjects: *CATALYTIC domains; *CAENORHABDITIS elegans; *SPINOCEREBELLAR ataxia

• Source: Aging Cell. Jan2020, Vol. 19 Issue 1, pN.PAG-N.PAG. 1p.

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The role of Ataxin-2 in Machado-Joseph disease: a molecular therapy approach with viral vectors

• Authors : Nobrega, Clevio

• Source: Generations. Fall, 2015, Vol. 43 Issue 3, p21, 1 p.

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Sharing of polyglutamine localization by the neuronal nucleus and cytoplasm in CAG-repeat diseases.

• Authors : Yamada, M.; Tan, C.-F.; Inenaga, C.

Subjects: GLUTAMINE; PROTEINS; NEURONS

• Source: Neuropathology & Applied Neurobiology. Dec2004, Vol. 30 Issue 6, p665-675. 11p.

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