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Academic Journal

Moderate intensity aerobic exercise alleviates motor deficits in 6-OHDA lesioned rats and reduces serum levels of biomarkers of Parkinson's disease severity without recovery of striatal dopamine or tyrosine hydroxylase.

  • Authors : Kasanga EA; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States of America.; Soto I

Subjects: Tyrosine 3-Monooxygenase*/Tyrosine 3-Monooxygenase*/Tyrosine 3-Monooxygenase*/metabolism ; Oxidopamine*/Oxidopamine*/Oxidopamine*/toxicity ; Corpus Striatum*/Corpus Striatum*/Corpus Striatum*/metabolism

  • Source: Experimental neurology [Exp Neurol] 2024 Sep; Vol. 379, pp. 114875. Date of Electronic Publication: 2024 Jun 27.Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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N -acetylcysteine increases dopamine release and prevents the deleterious effects of 6-OHDA on the expression of VMAT2, α-synuclein, and tyrosine hydroxylase.

  • Authors : El-Habta R; Department of Medical and Translational Biology, Umeå University, Umeå, Sweden.; Af Bjerkén S

Subjects: Vesicular Monoamine Transport Proteins*/Vesicular Monoamine Transport Proteins*/Vesicular Monoamine Transport Proteins*/metabolism ; Oxidopamine*/Oxidopamine*/Oxidopamine*/toxicity ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

  • Source: Neurological research [Neurol Res] 2024 May; Vol. 46 (5), pp. 406-415. Date of Electronic Publication: 2024 Mar 18.Publisher: Taylor & Francis Country of Publication: England NLM ID: 7905298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6-Hydroxydopamine-Treated Rats.

  • Authors : Narbute K; Department of Pharmacology, Faculty of Medicine, University of Latvia, Riga, Latvia.; Piļipenko V

Subjects: Administration, Intranasal/Administration, Intranasal/Administration, Intranasal/*methods ; Extracellular Vesicles/Extracellular Vesicles/Extracellular Vesicles/*metabolism ; Microscopy, Electron, Transmission/Microscopy, Electron, Transmission/Microscopy, Electron, Transmission/*methods

  • Source: Stem cells translational medicine [Stem Cells Transl Med] 2019 May; Vol. 8 (5), pp. 490-499. Date of Electronic Publication: 2019 Feb 01.Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Norepinephrine upregulates the expression of tyrosine hydroxylase and protects dopaminegic neurons against 6-hydrodopamine toxicity.

  • Authors : Zhu MY; Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA. Electronic address: .; Raza MU

Subjects: Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*drug effects ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*pharmacology ; Norepinephrine/Norepinephrine/Norepinephrine/*pharmacology

  • Source: Neurochemistry international [Neurochem Int] 2019 Dec; Vol. 131, pp. 104549. Date of Electronic Publication: 2019 Sep 17.Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion.

  • Authors : Kasanga EA; Institute for Healthy Aging , University of North Texas Health Science Center , Fort Worth , Texas 76107 , United States.; Owens CL

Subjects: Glial Cell Line-Derived Neurotrophic Factor/Glial Cell Line-Derived Neurotrophic Factor/Glial Cell Line-Derived Neurotrophic Factor/*pharmacology ; Glial Cell Line-Derived Neurotrophic Factor Receptors/Glial Cell Line-Derived Neurotrophic Factor Receptors/Glial Cell Line-Derived Neurotrophic Factor Receptors/*metabolism ; Oxidopamine/Oxidopamine/Oxidopamine/*toxicity

  • Source: ACS chemical neuroscience [ACS Chem Neurosci] 2019 Oct 16; Vol. 10 (10), pp. 4237-4249. Date of Electronic Publication: 2019 Oct 08.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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β-asarone increases MEF2D and TH levels and reduces α-synuclein level in 6-OHDA-induced rats via regulating the HSP70/MAPK/MEF2D/Beclin-1 pathway: Chaperone-mediated autophagy activation, macroautophagy inhibition and HSP70 up-expression.

  • Authors : Huang L; Lingnan Normal University, Zhanjiang 524048, PR China; Hainan Medical University, Haikou, 571199, PR China.

Subjects: Anisoles/Anisoles/Anisoles/*pharmacology ; Autophagy/Autophagy/Autophagy/*drug effects ; HSC70 Heat-Shock Proteins/HSC70 Heat-Shock Proteins/HSC70 Heat-Shock Proteins/*metabolism

  • Source: Behavioural brain research [Behav Brain Res] 2016 Oct 15; Vol. 313, pp. 370-379. Date of Electronic Publication: 2016 Jul 18.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium:

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Neonatal 6-hydroxydopamine administration to mice is fatal.

  • Authors : Brot MD; Department of Orthodontics, University of Washington, Seattle, Wash 98195-7370, USA.; Szczypka MS

Subjects: Adrenergic Agents/Adrenergic Agents/Adrenergic Agents/*pharmacology ; Dopamine/Dopamine/Dopamine/*deficiency ; Oxidopamine/Oxidopamine/Oxidopamine/*pharmacology

  • Source: Developmental neuroscience [Dev Neurosci] 2002; Vol. 24 (6), pp. 531-8.Publisher: Karger Country of Publication: Switzerland NLM ID: 7809375 Publication Model: Print Cited Medium: Print ISSN: 0378-5866 (Print)

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Neonatal 6-OHDA lesions upregulate adult expression of tyrosine hydroxylase mRNA.

  • Authors : Frohna PA; Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104-6141.; Neal-Beliveau BS

Subjects: Oxidopamine*; Animals, Newborn/Animals, Newborn/Animals, Newborn/*physiology ; RNA, Messenger/RNA, Messenger/RNA, Messenger/*biosynthesis

  • Source: Neuroreport [Neuroreport] 1993 Sep; Vol. 4 (9), pp. 1095-8.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100935 Publication Model: Print Cited Medium: Print ISSN:

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Quantitation of the levels of tyrosine hydroxylase and preproenkephalin mRNAs in nigrostriatal sites after 6-hydroxydopamine lesions.

  • Authors : Zhu YS; Department of Pharmacology, Cornell University Medical College, New York, NY 10021.; Jones SB

Subjects: Oxidopamine*; Brain Diseases/Brain Diseases/Brain Diseases/*genetics ; Brain Diseases/Brain Diseases/Brain Diseases/*metabolism

  • Source: Life sciences [Life Sci] 1993; Vol. 52 (19), pp. 1577-84.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print Cited Medium: Print ISSN: 0024-3205 (Print)

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Intraventricular injection of 6-hydroxydopamine results in an increased number of tyrosine hydroxylase immune-positive cells in the rat cortex.

  • Authors : Wachter B; Graduate School of Cellular & Molecular Neuroscience, University of Tübingen, Österbergstrasse 3, 72047 Tübingen, Germany.; Caradonna S

Subjects: Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*drug effects ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*enzymology ; Oxidopamine/Oxidopamine/Oxidopamine/*toxicity

  • Source: Neuroscience [Neuroscience] 2014 Nov 07; Vol. 280, pp. 99-110. Date of Electronic Publication: 2014 Sep 16.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  136 results for ""Oxidopamine""