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Academic Journal

Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease.

  • Authors : Nunes JA; Biological and Molecular Chemistry Research Group, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, AC. Simões Campus, Alagoas, Maceió, 57072-970, Brazil.; Santos-Júnior PFDS

Subjects: Coumarins*/Coumarins*/Coumarins*/chemistry ; Coumarins*/Coumarins*/Coumarins*/pharmacology ; Coumarins*/Coumarins*/Coumarins*/chemical synthesis

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2025 Feb 05; Vol. 283, pp. 117109. Date of Electronic Publication: 2024 Nov 28.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Antileishmanial and Antitrypanosomal Trends of Synthetic Tetralone Derivatives.

  • Authors : Alkhaldi AAM; Biology Department, College of Science, Jouf University, Sakaka, Aljouf, Saudi Arabia.; de Koning HP

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/drug effects ; Tetralones*/Tetralones*/Tetralones*/pharmacology ; Tetralones*/Tetralones*/Tetralones*/chemistry

  • Source: Drug development research [Drug Dev Res] 2025 Feb; Vol. 86 (1), pp. e70055.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299

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Academic Journal

AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei.

  • Authors : Black JA; Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP 14049-900, Brazil; University of Glasgow, Centre for Parasitology, School of Infection and Immunity, 120 University Place, Sir Graeme Davies Building, Glasgow G12 8TA, United Kingdom.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Chromosome Segregation*

  • Source: Molecular and biochemical parasitology [Mol Biochem Parasitol] 2025 Feb; Vol. 261, pp. 111664. Date of Electronic Publication: 2024 Dec 31.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8006324 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Graphene quantum dots disrupt the mitochondrial potential of Trypanosoma brucei by interacting with the p18 subunit of ATP synthase F 1 after endocytosis via the VSG recycling pathway.

  • Authors : Liu Y; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang 110866, China; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang 110866, China.

Subjects: Quantum Dots*/Quantum Dots*/Quantum Dots*/chemistry ; Quantum Dots*/Quantum Dots*/Quantum Dots*/metabolism ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism

  • Source: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Feb; Vol. 679 (Pt A), pp. 975-986. Date of Electronic Publication: 2024 Oct 11.Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

DRBD18 acts as a transcript-specific RNA editing auxiliary factor in Trypanosoma brucei .

  • Authors : Pandey P; Department of Microbiology and Immunology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York 14203, USA.; Wackowski K

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; RNA Editing*

  • Source: RNA (New York, N.Y.) [RNA] 2025 Jan 22; Vol. 31 (2), pp. 245-257. Date of Electronic Publication: 2025 Jan 22.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium:

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Academic Journal

Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei.

  • Authors : Krasiļņikova M; University of Glasgow Centre for Parasitology, The Wellcome Centre for Integrative Parasitology, University of Glasgow, School of Infection and Immunity, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA, United Kingdom.; Marques CA

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; DNA Replication*/DNA Replication*/DNA Replication*/genetics

  • Source: Nature communications [Nat Commun] 2025 Jan 16; Vol. 16 (1), pp. 751. Date of Electronic Publication: 2025 Jan 16.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex.

  • Authors : Bernhard H; EMBL Grenoble, 71 Avenue des Martyrs, Grenoble, France.; Institut de Biologie Structurale (IBS), Université Grenoble Alpes (UGA), Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Centre National de la Recherche Scientifique (CNRS), Grenoble, France.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; RNA, Spliced Leader*/RNA, Spliced Leader*/RNA, Spliced Leader*/metabolism

  • Source: Nature communications [Nat Commun] 2025 Jan 15; Vol. 16 (1), pp. 685. Date of Electronic Publication: 2025 Jan 15.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

KRBP72 facilitates ATPase-dependent editing progression through a structural roadblock in mitochondrial A6 mRNA.

  • Authors : Dubey AP; Department of Microbiology and Immunology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, 955 Main Street, Buffalo, NY 14203, USA.; Tylec BL

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/enzymology ; RNA, Messenger*/RNA, Messenger*/RNA, Messenger*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Jan 11; Vol. 53 (2).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The kinetoplastid kinetochore protein KKT23 acetyltransferase is a structural homolog of GCN5 that acetylates the histone H2A C-terminal tail.

  • Authors : Ludzia P; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.; Ishii M

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/enzymology ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Protozoan Proteins*/Protozoan Proteins*/Protozoan Proteins*/chemistry

  • Source: Structure (London, England : 1993) [Structure] 2025 Jan 02; Vol. 33 (1), pp. 123-135.e10. Date of Electronic Publication: 2024 Nov 22.Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes.

  • Authors : Rabuffo C; Division of Experimental Parasitology, Faculty of Veterinary Medicine, Ludwig-Maximilians-Universität München, 82152, Planegg-Martinsried, Germany.; Biomedical Center Munich, Division of Physiological Chemistry, Ludwig-Maximilians-Universität München, 82152, Planegg-Martinsried, Germany.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Genome, Protozoan*

  • Source: Nature communications [Nat Commun] 2024 Dec 23; Vol. 15 (1), pp. 10716. Date of Electronic Publication: 2024 Dec 23.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  6,968 results for ""Trypanosoma brucei brucei""