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Plant polysaccharides attenuate fluorouracil toxicity for the small intestinal epithelium

• Authors : Safonova, E.A.; Lopatina, K.A.; Vychuzhanina, A.V.

• Source: Bulletin of Experimental Biology and Medicine. June, 2016, Vol. 161 Issue 2, p308, 4 p.

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Use of uridine triacetate for the management of fluorouracil overdose.

• Authors : McEvilly, Margaret¹ ; Popelas, Carl²; Tremmel, Bob³

Subjects: *ANTIDOTES; *ORPHAN drugs; *COLON tumors

• Source: American Journal of Health-System Pharmacy. 10/1/2011, Vol. 68 Issue 19, p1806-1809. 4p.

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MIR27A Gene Polymorphism Modifies the Effect of Common DPYD Gene Variants on Severe Toxicity in Patients with Gastrointestinal Tumors Treated with Fluoropyrimidine-Based Anticancer Therapy.

• Authors : Ikonnikova, Anna; Fedorinov, Denis; Gryadunov, Dmitry

Subjects: DIHYDROPYRIMIDINE dehydrogenase; GENETIC variation; GENETIC polymorphisms

• Source: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 15, p8503, 13p

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Case report of capecitabine toxicity and use of uridine triacetate.

• Authors : Oliver, Wesley D.; Duffy, Alison P.; Hausner, Petr F.

Subjects: NUCLEOSIDES; THERAPEUTIC use of antimetabolites; ANTIMETABOLITES

• Source: Journal of Oncology Pharmacy Practice; Mar2019, Vol. 25 Issue 2, p470-473, 4p, 2 Charts

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Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?

• Authors : Maslarinou, Anthi; Manolopoulos, Vangelis G.; Ragia, Georgia

Subjects: FLUOROPYRIMIDINES; DIHYDROPYRIMIDINE dehydrogenase; BIOTRANSFORMATION (Metabolism)

• Source: Frontiers in Pharmacology; 2023, p1-22, 22p

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Posible influencia de factores no controlados en las concentraciones séricas de uracilo.

• Authors : A., Repilado-Álvarez; M. T., Llorente-Ballesteros; J., Hurtado-de-Mendoza

Subjects: DIHYDROPYRIDINE; MASS spectrometers; DEHYDROGENASES

• Source: Sanidad Militar; ene-mar2023, Vol. 79 Issue 1, p35-41, 7p

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DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview.

• Authors : Paulsen, Niels Herluf; Vojdeman, Fie; Andersen, Stig Ejdrup

Subjects: DIHYDROPYRIMIDINE dehydrogenase; ENZYME deficiency; ONCOLOGYEUROPEAN Medicines Agency

• Source: Basic & Clinical Pharmacology & Toxicology; Nov2022, Vol. 131 Issue 5, p325-346, 22p

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Case report: Uridine triacetate in the management of delayed onset 5-fluorouracil toxicity: A case report and review of literature.

• Authors : Jacob, Aasems; Veedu, Janeesh Sekkath; Selene, Insija

Subjects: URIDINE; ANTIMETABOLITES; ANTINEOPLASTIC agents

• Source: Frontiers in Pharmacology; 9/7/2022, Vol. 12, p01-05, 5p

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Effects of polymorphisms in the MTHFR gene on 5-FU hematological toxicity and efficacy in Thai colorectal cancer patients.

• Authors : Atasilp, Chalirmporn; Lenavat, Rinradee; Vanwong, Natchaya

Subjects: COLORECTAL cancer; CANCER patients; FLUOROURACIL

• Source: Frontiers in Oncology; 7/15/2022, Vol. 12, p1-8, 8p

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Racial and ethnic differences in capecitabine toxicity in patients with gastrointestinal tract cancers.

• Authors : Brazelton, Alicia; Yande, Soham; Pope, Rita

Subjects: ETHNIC differences; HAND-foot syndrome; GASTROINTESTINAL cancer

• Source: Annals of Gastroenterology; 2022, Vol. 35 Issue 2, p182-186, 5p

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