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Saposins utilize two strategies for lipid transfer and CD1 antigen presentation.

• Authors : León, Luis; Tatituri, Raju V. V.; Grenha, Rosa

Subjects: SAPOSINS; LIPID transfer protein; PROTEIN-lipid interactions

• Source: Proceedings of the National Academy of Sciences of the United States of America; 3/20/2012, Vol. 109 Issue 12, p4357-4364, 8p

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Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells.

• Authors : Kang, Suk-Jo; Cresswell, Peter

Subjects: LIPIDS; T cells; MOLECULES

• Source: Nature Immunology; Feb2004, Vol. 5 Issue 2, p175-181, 7p

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Education Full Text (H.W. Wilson)

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Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

• Authors : Weiming Yuan; Xiaoyang Qi; Pansy Tsang

Subjects: ANTIGENS; IMMUNOGLOBULINS; GLYCOPROTEINS

• Source: Proceedings of the National Academy of Sciences of the United States of America; 3/27/2007, Vol. 104 Issue 13, p5551-5556, 6p

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The Ins and Outs of CD1 Molecules: Bringing Lipids Under Immunological Surveillance.

• Authors : Gumperz, Jenny E.

Subjects: LIPIDS; ANTIGENS; GLYCOPROTEINS

• Source: Traffic; Jan2006, Vol. 7 Issue 1, p2-13, 12p, 2 Color Photographs, 2 Diagrams

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CD1d function is regulated by microsomal triglyceride transfer protein.

• Authors : Brozovic, Suzana; Nagaishi, Takashi; Yoshida, Masaru

Subjects: HISTOCOMPATIBILITY; MOLECULES; GLYCOLIPIDS

• Source: Nature Medicine; May2004, Vol. 10 Issue 5, p535-539, 5p

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Novel lipid antigens for NKT cells in cancer.

• Authors : Lee, Michael S.; Webb, Tonya J.

Subjects: T cell receptors; CANCER cells; CELLULAR recognition

• Source: Frontiers in Immunology; 2023, p1-12, 12p

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Saposin C is required for lipid presentation by human CD1b.

• Authors : Winau, Florain; Schwierzeck, Vera; Hurwitz, Robert

Subjects: LIPIDS; MYCOBACTERIUM tuberculosis; PROTEINS

• Source: Nature Immunology; Feb2004, Vol. 5 Issue 2, p169-174, 6p

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Education Full Text (H.W. Wilson)

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Presenting fats with SAPs.

• Authors : Kronenberg, Mitchell

Subjects: CD antigens; LIPIDS; T cells

• Source: Nature Immunology; Feb2004, Vol. 5 Issue 2, p126-127, 2p

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