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Academic Journal

Associations of the SLCO1B1 Polymorphisms With Hepatic Function, Baseline Lipid Levels, and Lipid-lowering Response to Simvastatin in Patients With Hyperlipidemia.

  • Authors : Wu X; School of Life Sciences, Anhui University, Hefei, China.; Institute of Physical Science and Information Technology, Anhui University, Hefei, China.

Subjects: Alleles* ; Haplotypes* ; Hyperlipidemias*/Hyperlipidemias*/Hyperlipidemias*/blood

  • Source: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2018 Dec; Vol. 24 Publisher: Sage Publications Country of Publication: United States NLM ID: 9508125 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Simvastatin-related myopathy in shift workers: a report of two cases.

Subjects: Hypolipidemic Agents/Hypolipidemic Agents/Hypolipidemic Agents/*pharmacology ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Muscular Diseases/Muscular Diseases/Muscular Diseases/*drug therapy

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2018 Sep 25; Vol. 33 (3), pp. 153-156.Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Print Cited Medium: Internet ISSN: 2363-8915

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Academic Journal

Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics.

  • Authors : Wagner JB; Ward Family Heart Center, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO, USA.; Division of Clinical Pharmacology, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO, USA.

Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacokinetics ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics ; Simvastatin/Simvastatin/Simvastatin/*analogs & derivatives

  • Source: Journal of clinical pharmacology [J Clin Pharmacol] 2018 Jun; Vol. 58 (6), pp. 823-833. Date of Electronic Publication: 2018 Feb 22.Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604

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Academic Journal

Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.

  • Authors : Poller B; Novartis Institutes for Biomedical Research, Basel, Switzerland.; Woessner R

Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacokinetics ; Indoleacetic Acids/Indoleacetic Acids/Indoleacetic Acids/*pharmacology ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics

  • Source: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2019 Aug; Vol. 57, pp. 101809. Date of Electronic Publication: 2019 Jun 10.Publisher: Academic Press Country of Publication: England NLM ID: 9715279 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A case of simvastatin-induced myopathy with SLCO1B1 genetic predisposition and co-ingestion of linagliptin and Stevia rebaudiana.

  • Authors : Chan JCM; Division of Clinical Pharmacology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.; Prince of Wales Hospital Poison Treatment Centre, Prince of Wales Hospital, Hospital Authority, Shatin, Hong Kong SAR, China.

Subjects: Genetic Predisposition to Disease/Genetic Predisposition to Disease/Genetic Predisposition to Disease/*genetics ; Linagliptin/Linagliptin/Linagliptin/*administration & dosage ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*genetics

  • Source: Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2019 Jun; Vol. 44 (3), pp. 381-383. Date of Electronic Publication: 2019 Feb 03.Publisher: Country of Publication: England NLM ID: 8704308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2710

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Academic Journal

Lack of association between SLCO1B1 polymorphisms and lipid-lowering response to simvastatin therapy in Thai hypercholesterolaemic patients.

Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use ; Hypercholesterolemia/Hypercholesterolemia/Hypercholesterolemia/*drug therapy ; Hypercholesterolemia/Hypercholesterolemia/Hypercholesterolemia/*genetics

  • Source: Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2018 Oct; Vol. 43 (5), pp. 647-655. Date of Electronic Publication: 2018 Mar 25.Publisher: Country of Publication: England NLM ID: 8704308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2710

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Academic Journal

Candidate-Gene Study of Functional Polymorphisms in SLCO1B1 and CYP3A4/5 and the Cholesterol-Lowering Response to Simvastatin.

  • Authors : Kitzmiller JP; Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.; Luzum JA

Subjects: Genetic Association Studies*; Cholesterol/Cholesterol/Cholesterol/*blood ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics

  • Source: Clinical and translational science [Clin Transl Sci] 2017 May; Vol. 10 (3), pp. 172-177. Date of Electronic Publication: 2016 Nov 04.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The influences of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of simvastatin, in relation to CYP3A4 inhibition.

  • Authors : Jiang F; Clinical Research Division, National Institute of Food & Drug Safety Evaluation, Ministry of Food & Drug Safety, Cheongju, Republic of Korea.; Choi JY

Subjects: Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics ; Cytochrome P-450 CYP3A Inhibitors/Cytochrome P-450 CYP3A Inhibitors/Cytochrome P-450 CYP3A Inhibitors/*pharmacokinetics ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacokinetics

  • Source: Pharmacogenomics [Pharmacogenomics] 2017 Apr; Vol. 18 (5), pp. 459-469. Date of Electronic Publication: 2017 Mar 28.Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 100897350 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genomewide Association Study of Simvastatin Pharmacokinetics.

  • Authors : Mykkänen AJH; Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki, Finland.

Subjects: Organic Anion Transporters*/Organic Anion Transporters*/Organic Anion Transporters*/genetics ; Simvastatin*/Simvastatin*/Simvastatin*/pharmacokinetics; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/genetics

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Sep; Vol. 112 (3), pp. 676-686. Date of Electronic Publication: 2022 Jun 24.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

Physiologically Based Precision Dosing Approach for Drug-Drug-Gene Interactions: A Simvastatin Network Analysis.

  • Authors : Wojtyniak JG; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.

Subjects: Drug Interactions/Drug Interactions/Drug Interactions/*genetics ; Simvastatin/Simvastatin/Simvastatin/*administration & dosage; ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jan; Vol. 109 (1), pp. 201-211. Date of Electronic Publication: 2020 Dec 06.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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  • 1-10 of  44 results for ""Liver-Specific Organic Anion Transporter 1""