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Academic Journal

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

Subjects: Signal Transduction*; CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*immunology ; Immunological Synapses/Immunological Synapses/Immunological Synapses/*metabolism

  • Source: Haematologica [Haematologica] 2011 Oct; Vol. 96 (10), pp. 1415-23. Date of Electronic Publication: 2011 Jun 09.Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

WASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor site.

  • Authors : Pauker MH; From the Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel.; Reicher B

Subjects: Signal Transduction*; Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/*metabolism ; Wiskott-Aldrich Syndrome Protein/Wiskott-Aldrich Syndrome Protein/Wiskott-Aldrich Syndrome Protein/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2014 Dec 12; Vol. 289 (50), pp. 34503-19. Date of Electronic Publication: 2014 Oct 23.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Wiskott-Aldrich syndrome protein is an effector of Kit signaling.

  • Authors : Mani M; Division of Stem Cell Transplantation, Department of Pediatrics, Stanford University School of Medicine, CA 94305-5208, USA.; Venkatasubrahmanyam S

Subjects: Gene Expression Regulation* ; Signal Transduction*; Proto-Oncogene Proteins c-kit/Proto-Oncogene Proteins c-kit/Proto-Oncogene Proteins c-kit/*metabolism

  • Source: Blood [Blood] 2009 Oct 01; Vol. 114 (14), pp. 2900-8. Date of Electronic Publication: 2009 Jul 30.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intrabodies against the EVH1 domain of Wiskott-Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells.

  • Authors : Sato M; Department of Molecular Biology and Immunology, National Institute of Agrobiological Sciences, Ibaraki, Japan.; Iwaya R

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*metabolism ; Intracellular Space/Intracellular Space/Intracellular Space/*immunology ; Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/*metabolism

  • Source: The FEBS journal [FEBS J] 2005 Dec; Vol. 272 (23), pp. 6131-44.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

WASP is activated by phosphatidylinositol-4,5-bisphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling.

  • Authors : Khuong TM; Department of Molecular and Developmental Genetics, VIB, Center for Human Genetics, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.; Habets RL

Subjects: Bone Morphogenetic Proteins/Bone Morphogenetic Proteins/Bone Morphogenetic Proteins/*metabolism ; Phosphatidylinositol 4,5-Diphosphate/Phosphatidylinositol 4,5-Diphosphate/Phosphatidylinositol 4,5-Diphosphate/*metabolism ; Signal Transduction/Signal Transduction/Signal Transduction/*physiology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Oct 05; Vol. 107 (40), pp. 17379-84. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state.

  • Authors : Stabile H; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.; Carlino C

Subjects: Cell Movement/Cell Movement/Cell Movement/*immunology ; Genetic Diseases, X-Linked/Genetic Diseases, X-Linked/Genetic Diseases, X-Linked/*immunology ; Killer Cells, Natural/Killer Cells, Natural/Killer Cells, Natural/*immunology

  • Source: Blood [Blood] 2010 Apr 08; Vol. 115 (14), pp. 2818-26. Date of Electronic Publication: 2010 Feb 03.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells.

  • Authors : Bertet C; IBDML, UMR6216 CNRS-Université de la Méditerranée, Campus de Luminy, case 907, 13288 Marseille Cedex 09, France.; Rauzi M

Subjects: Epithelial Cells*/Epithelial Cells*/Epithelial Cells*/cytology ; Epithelial Cells*/Epithelial Cells*/Epithelial Cells*/physiology ; Signal Transduction*

  • Source: Development (Cambridge, England) [Development] 2009 Dec; Vol. 136 (24), pp. 4199-212.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP.

  • Authors : Falet H; Division of Translational Medicine, Brigham and Women's Hospital, One Blackfan Cir, Karp 6, Boston, MA02115, USA. ; Marchetti MP

Subjects: Blood Platelets/Blood Platelets/Blood Platelets/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Immunoglobulin A/Immunoglobulin A/Immunoglobulin A/*immunology

  • Source: Blood [Blood] 2009 Nov 19; Vol. 114 (21), pp. 4729-37. Date of Electronic Publication: 2009 Aug 19.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Specific binding of the WASP N-terminal domain to Btk is critical for TLR2 signaling in macrophages.

  • Authors : Sakuma C; Animal Immune and Cell Biology Research Unit, National Institute of Agrobiological Sciences, 1-2 Ohwashi, Tsukuba, Ibaraki 305-8634, Japan.; Sato M

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Macrophages/Macrophages/Macrophages/*metabolism ; Protein-Tyrosine Kinases/Protein-Tyrosine Kinases/Protein-Tyrosine Kinases/*metabolism

  • Source: Molecular immunology [Mol Immunol] 2015 Feb; Vol. 63 (2), pp. 328-36. Date of Electronic Publication: 2014 Sep 10.Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp.

  • Authors : Sato R; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University Graduate School of Medicine, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.; Iiizumi S

Subjects: Signal Transduction*; Apoptosis/Apoptosis/Apoptosis/*genetics ; Precursor Cells, B-Lymphoid/Precursor Cells, B-Lymphoid/Precursor Cells, B-Lymphoid/*metabolism

  • Source: International journal of hematology [Int J Hematol] 2012 Mar; Vol. 95 (3), pp. 299-310. Date of Electronic Publication: 2012 Feb 05.Publisher: Springer Japan Country of Publication: Japan NLM ID: 9111627 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  337 results for ""Wiskott-Aldrich Syndrome Protein""