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Subject : signal transduction

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Academic Journal

Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.

Authors : Lee CJ; Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea.; Lee HS

Subjects: Cell Cycle/Cell Cycle/Cell Cycle/*drug effects ; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*drug effects ; Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/*antagonists & inhibitors

Source: Carcinogenesis [Carcinogenesis] 2014 Feb; Vol. 35 (2), pp. 432-41. Date of Electronic Publication: 2013 Sep 12.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation.

Authors : Liu K; Hormel Institute, University of Minnesota, Austin, Minnesota 55912, USA.; Cho YY

Subjects: Activating Transcription Factor 1/Activating Transcription Factor 1/Activating Transcription Factor 1/*metabolism ; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*chemically induced ; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*metabolism

Source: The Journal of biological chemistry [J Biol Chem] 2011 Jan 21; Vol. 286 (3), pp. 2057-66. Date of Electronic Publication: 2010 Nov 22.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

B-cell intrinsic RANK signaling cooperates with TCL1 to induce lineage-dependent B-cell transformation.

Authors : Pfeuffer L; Institute of Clinical Chemistry and Pathobiochemistry, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; TranslaTUM - Central Institute for Translational Cancer Research, Technical University of Munich, Munich, Germany.

Subjects: Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/metabolism ; Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/genetics ; Signal Transduction*

Source: Blood cancer journal [Blood Cancer J] 2024 Aug 28; Vol. 14 (1), pp. 151. Date of Electronic Publication: 2024 Aug 28.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Knockdown of NIK and IKKβ-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-κΒ Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.

Authors : Qin, Mengbin¹; Zhang, Jinxiu¹; Xu, Chunyan¹

Subjects: *COLON cancer treatment; *NEOPLASTIC cell transformation; *GENETICS of colon cancer

Source: PLoS ONE. 1/26/2017, Vol. 12 Issue 1, p1-13. 13p.

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Academic Journal

Conserved Mechanisms of Tumorigenesis in the Drosophila Adult Midgut.

Authors : Martorell, Òscar^1,2; Merlos-Suárez, Anna³; Campbell, Kyra^1,2

Subjects: *COLON cancer; *NEOPLASTIC cell transformation; *DROSOPHILA

Source: PLoS ONE. Feb2014, Vol. 9 Issue 2, p1-10. 10p.

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Academic Journal

Galactosylceramide Affects Tumorigenic and Metastatic Properties of Breast Cancer Cells as an Anti-Apoptotic Molecule.

Authors : Owczarek, Tomasz B.^1,2; Suchanski, Jarosław²; Pula, Bartosz³

Subjects: *GALACTOSYLCERAMIDES; *NEOPLASTIC cell transformation; *CANCER invasiveness

Source: PLoS ONE. Dec2013, Vol. 8 Issue 12, p1-10. 10p.

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Academic Journal

Unique Haploinsufficient Role of the MicroRNA-Processing Molecule Dicer1 in a Murine Colitis-Associated Tumorigenesis Model.

Authors : Yoshikawa, Takeshi¹; Otsuka, Motoyuki^1,2 ; Kishikawa, Takahiro¹

Subjects: *NEOPLASTIC cell transformation; *MICRORNA; *DICEROS

Source: PLoS ONE. Sep2013, Vol. 8 Issue 9, p1-9. 9p.

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Academic Journal

LKB1 Inhibits Breast Cancer Partially through Repressing the Hedgehog Signaling Pathway.

Authors : Zhuang, Zhigang¹; Wang, Kai¹; Cheng, Xiaolin¹

Subjects: *BREAST cancer research; *NEOPLASTIC cell transformation; *GENE expression

Source: PLoS ONE. Jul2013, Vol. 8 Issue 7, p1-9. 9p.

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Academic Journal

Loss of lkb1 Expression Reduces the Latency of ErbB2-Mediated Mammary Gland Tumorigenesis, Promoting Changes in Metabolic Pathways.

Authors : Andrade-Vieira, Rafaela¹; Xu, Zhaolin²; Colp, Patricia²

Subjects: *MAMMARY gland tumors; *NEOPLASTIC cell transformation; *GENE expression

Source: PLoS ONE. Feb2013, Vol. 8 Issue 2, p1-10. 10p.

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Academic Journal

Altered Prostanoid Signaling Contributes to Increased Skin Tumorigenesis in Tpl2 Knockout Mice.

Authors : DeCicco-Skinner, Kathleen L.¹; Nolan, Sabrina J.¹; Deshpande, Monika M.²

Subjects: *PROSTANOIDS; *NEOPLASTIC cell transformation; *SKIN cancer

Source: PLoS ONE. Feb2013, Vol. 8 Issue 2, p1-9. 9p.

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