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Academic Journal

HNF1ɑ promotes colorectal cancer progression via HKDC1-mediated activation of AKT/AMPK signaling pathway.

  • Authors : Yang W; Department of Colorectal Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian 350014, China; Fujian Medical University, Fuzhou, Fujian 350122, China.

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

  • Source: Gene [Gene] 2024 Nov 30; Vol. 928, pp. 148752. Date of Electronic Publication: 2024 Jul 08.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Protective effects of cilostazol via the HNF1α/FXR signalling pathway and anti-apoptotic mechanisms in a rat model of estrogen-induced intrahepatic cholestasis.

  • Authors : Hassan M; Immunology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, P.O. box 30, Imbaba, 12411, Giza, Egypt.; Salem MB

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 01; Vol. 14 (1), pp. 22751. Date of Electronic Publication: 2024 Oct 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Study on the molecular mechanisms of rifaximin in the treatment of non‑alcoholic steatohepatitis based on the Helicobacter ‑DCA‑Fxr‑Hnf1α signalling pathway.

  • Authors : Wan YP; Department of Gastroenterology, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.; Li S

Subjects: Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/drug therapy ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/pathology

  • Source: Molecular medicine reports [Mol Med Rep] 2025 Feb; Vol. 31 (2). Date of Electronic Publication: 2024 Nov 29.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The age-dependent regulation of pancreatic islet landscape is fueled by a HNF1a-immune signaling loop.

  • Authors : Mathisen AF; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Legøy TA

Subjects: Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/metabolism ; Islets of Langerhans*/Islets of Langerhans*/Islets of Langerhans*/metabolism ; Signal Transduction*/Signal Transduction*/Signal Transduction*/physiology

  • Source: Mechanisms of ageing and development [Mech Ageing Dev] 2024 Aug; Vol. 220, pp. 111951. Date of Electronic Publication: 2024 May 31.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 0347227 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HMGB1 Inhibits HNF1A to Modulate Liver Fibrogenesis via p65/miR-146b Signaling.

  • Authors : Ge S; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.; Wu X

Subjects: Signal Transduction*; HMGB1 Protein/HMGB1 Protein/HMGB1 Protein/*metabolism ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism

  • Source: DNA and cell biology [DNA Cell Biol] 2020 Sep; Vol. 39 (9), pp. 1711-1722. Date of Electronic Publication: 2020 Aug 20.Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription.

Subjects: Gene Expression Regulation, Neoplastic* ; Signal Transduction* ; Transcription, Genetic*

  • Source: The Journal of clinical investigation [J Clin Invest] 2017 May 01; Vol. 127 (5), pp. 1873-1888. Date of Electronic Publication: 2017 Apr 10.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

HNF1A/CASC2 regulates pancreatic cancer cell proliferation through PTEN/Akt signaling.

  • Authors : Yu Y; Department of Pancreatic Biliary Surgery, Xiangya Hospital, Central South University, Changsha, China.; Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Guilin Medical College, Guilin, Guangxi, China.

Subjects: Signal Transduction*; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism ; PTEN Phosphohydrolase/PTEN Phosphohydrolase/PTEN Phosphohydrolase/*metabolism

  • Source: Journal of cellular biochemistry [J Cell Biochem] 2019 Mar; Vol. 120 (3), pp. 2816-2827. Date of Electronic Publication: 2018 Nov 30.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α.

  • Authors : Bao C; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200032, China.; Li Y

Subjects: Signal Transduction*; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism

  • Source: Science signaling [Sci Signal] 2015 Jul 28; Vol. 8 (387), pp. ra75. Date of Electronic Publication: 2015 Jul 28.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited

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Academic Journal

Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.

  • Authors : Farrelly AM; Department of Endocrinology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.; Kilbride SM

Subjects: Signal Transduction* ; Sirolimus*/Sirolimus*/Sirolimus*/pharmacology ; Sirolimus*/Sirolimus*/Sirolimus*/therapeutic use

  • Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2011 Nov; Vol. 16 (11), pp. 1128-37.Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Print Cited Medium: Internet ISSN: 1573-675X

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Academic Journal

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal.

  • Authors : Yi F; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S Ashland Avenue, MBRB 2270, M/C 669, Chicago, Illinois 60607, USA.; Pereira L

Subjects: Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/genetics

  • Source: Nature cell biology [Nat Cell Biol] 2011 Jun 19; Vol. 13 (7), pp. 762-70. Date of Electronic Publication: 2011 Jun 19.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  42 results for ""Hepatocyte Nuclear Factor 1-alpha""