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Academic Journal

GATA1-mediated macrophage polarization via TrkB/cGMP-PKG signaling pathway to promote the development of preeclampsia.

  • Authors : Li W; Department of Obstetrics and Gynecology, Cheeloo College of Medicine, Shandong University, Ji'nan City, Shandong Province, China.; Department of Obstetrics, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Ji'nan City, Shandong Province, China.

Subjects: Pre-Eclampsia*/Pre-Eclampsia*/Pre-Eclampsia*/metabolism ; Pre-Eclampsia*/Pre-Eclampsia*/Pre-Eclampsia*/genetics ; Signal Transduction*

  • Source: European journal of medical research [Eur J Med Res] 2025 Jan 07; Vol. 30 (1), pp. 12. Date of Electronic Publication: 2025 Jan 07.Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X

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Academic Journal

Chemoprotective Mechanism of Sodium Thiosulfate Against Cisplatin-Induced Nephrotoxicity Is via Renal Hydrogen Sulfide, Arginine/cAMP and NO/cGMP Signaling Pathways.

  • Authors : Dugbartey GJ; Department of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, Accra P.O. Box LG43, Ghana.; Department of Physiology and Pharmacology, Accra College of Medicine, Accra P.O. Box CT9828, Ghana.

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/adverse effects ; Thiosulfates*/Thiosulfates*/Thiosulfates*/pharmacology ; Hydrogen Sulfide*/Hydrogen Sulfide*/Hydrogen Sulfide*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 04; Vol. 26 (1). Date of Electronic Publication: 2025 Jan 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Choline metabolism modulates cyclic-di-GMP signaling and virulence of Pseudomonas aeruginosa in a macrophage infection model.

  • Authors : Zhou Y; Shenzhen Third People's Hospital, National Clinical Research Centre for Infectious Disease, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.; Department of Laboratory Medicine, Shenzhen University General Hospital, Shenzhen, 518000, China.

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/pathogenicity ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/metabolism ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics

  • Source: BMC infectious diseases [BMC Infect Dis] 2024 Dec 27; Vol. 24 (1), pp. 1466. Date of Electronic Publication: 2024 Dec 27.Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334

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Academic Journal

Regulation and Pharmacology of the Cyclic GMP and Nitric Oxide Pathway in Embryonic and Adult Stem Cells.

  • Authors : Kots AY; Veteran Affairs Palo Alto Health Care System, US Department of Veteran Affairs, Palo Alto, CA 90304, USA.; Bian K

Subjects: Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/cytology ; Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/drug effects ; Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/metabolism

  • Source: Cells [Cells] 2024 Dec 05; Vol. 13 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Endothelial oestrogen-myocardial cyclic guanosine monophosphate axis critically determines angiogenesis and cardiac performance during pressure overload.

  • Authors : Fukuma N; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-8655, Japan.; Division of Cardiology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Subjects: Estrogen Receptor alpha*/Estrogen Receptor alpha*/Estrogen Receptor alpha*/metabolism ; Estrogen Receptor alpha*/Estrogen Receptor alpha*/Estrogen Receptor alpha*/genetics ; Estrogen Receptor alpha*/Estrogen Receptor alpha*/Estrogen Receptor alpha*/deficiency

  • Source: Cardiovascular research [Cardiovasc Res] 2024 Dec 04; Vol. 120 (15), pp. 1884-1897.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245

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Academic Journal

Deletion of AT 1a receptors selectively in the proximal tubules of the kidney alters the hypotensive and natriuretic response to atrial natriuretic peptide via NPR A /cGMP/NO signaling.

  • Authors : Li XC; Tulane Hypertension and Renal Center of Excellence and Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana, United States.; Wang CH

Subjects: Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/metabolism ; Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/Kidney Tubules, Proximal*/drug effects ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism

  • Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2024 Dec 01; Vol. 327 (6), pp. F946-F956. Date of Electronic Publication: 2024 Oct 03.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Modified Zhenwu Decoction improved intestinal barrier function of experimental colitis through activation of sGC-mediated cGMP/PKG signaling.

  • Authors : Xu Y; Centre for Chinese Herbal Medicine Drug Development, Hong Kong Baptist University, Hong Kong SAR, China.; Huang C

Subjects: Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/pharmacology ; Mice, Inbred C57BL* ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism

  • Source: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Nov 15; Vol. 334, pp. 118570. Date of Electronic Publication: 2024 Jul 11.Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The expression of contextual fear conditioning involves the dorsal hippocampus TRPV1 receptor interacting with the NMDA/NO/cGMP signalling pathway.

  • Authors : Bertacchini GL; State University of Mato Grosso do Sul - Medicine UEMS, Campo Grande, Brazil.; Department of Pharmacology, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

Subjects: TRPV Cation Channels*/TRPV Cation Channels*/TRPV Cation Channels*/metabolism ; Fear*/Fear*/Fear*/physiology ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism

  • Source: British journal of pharmacology [Br J Pharmacol] 2025 Feb; Vol. 182 (4), pp. 1107-1120. Date of Electronic Publication: 2024 Nov 12.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes.

  • Authors : Rutkowski N; Department II Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Cluster of Excellence Cellular Stress Responses in Aging- associated Diseases (CECAD), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Subjects: Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism ; Podocytes*/Podocytes*/Podocytes*/metabolism ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 30; Vol. 14 (1), pp. 26099. Date of Electronic Publication: 2024 Oct 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploring PKG signaling as a therapeutic avenue for pressure overload, ischemia, and HFpEF.

  • Authors : Zhazykbayeva S; Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University Bochum, Bochum, Germany.; Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University Bochum, Bochum, Germany.

Subjects: Cyclic GMP-Dependent Protein Kinases*/Cyclic GMP-Dependent Protein Kinases*/Cyclic GMP-Dependent Protein Kinases*/metabolism ; Signal Transduction* ; Heart Failure*/Heart Failure*/Heart Failure*/physiopathology

  • Source: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2024 Oct; Vol. 28 (10), pp. 857-873. Date of Electronic Publication: 2024 Sep 27.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  918 results for ""CYCLIC guanylic acid""