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Hypertonicity during a rapid rise in D-glucose mediates first-phase insulin secretion.

• Authors : Kamat, Varun; Sweet, Ian R.

Subjects: INSULIN aspart; INSULIN; BIPHASIC insulin

• Source: Frontiers in Endocrinology; 2024, p1-19, 19p

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Exploring the relationship between pancreatic fat and insulin secretion in overweight or obese women without type 2 diabetes mellitus: A preliminary investigation of the TOFI_Asia cohort.

• Authors : Sequeira, Ivana R.; Yip, Wilson; Lu, Louise W.

Subjects: TYPE 2 diabetes; OBESITY in women; BIPHASIC insulinASIA

• Source: PLoS ONE; 12/30/2022, Vol. 17 Issue 12, p1-15, 15p

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Improved postprandial glycemic control with biphasic insulin aspart relative to biphasic insulin lispro and biphasic human insulin in patients with type 2 diabetes.

• Authors : Hermansen, Kjeld; Colombo, Michele; Storgaard, Heidi

Subjects: GLUCOSE; TYPE 2 diabetes treatment; INSULIN therapy

• Source: Diabetes Care; May2002, Vol. 25 Issue 5, p883-888, 6p, 1 Diagram

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Integrated multiscale mathematical modeling of insulin secretion reveals the role of islet network integrity for proper oscillatory glucose-dose response.

• Authors : Stamper, I. Johanna¹ (AUTHOR) ; Wang, Xujing^1,2 (AUTHOR)

Subjects: *MULTISCALE modeling; *BIPHASIC insulin; *SECRETION

• Source: Journal of Theoretical Biology. Aug2019, Vol. 475, p1-24. 24p.

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Gluconeogenic Enzymes in β-Cells: Pharmacological Targets for Improving Insulin Secretion.

• Authors : Westermeier, Francisco¹ (AUTHOR); Holyoak, Todd¹ (AUTHOR); Asenjo, Joel L.¹ (AUTHOR)

Subjects: *BIPHASIC insulin; *SECRETION; *INSULIN

• Source: Trends in Endocrinology & Metabolism. Aug2019, Vol. 30 Issue 8, p520-531. 12p.

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miR-124a expression contributes to the monophasic pattern of insulin secretion in islets from pregnant rats submitted to a low-protein diet.

• Authors : de Siqueira, Kariny Cassia; de Lima, Faena Moura; Lima, Fernanda Souza

Subjects: ANIMALS; CALCIUM-binding proteins; CELL physiology

• Source: European Journal of Nutrition. Jun2018, Vol. 57 Issue 4, p1471-1483. 13p. 1 Chart, 8 Graphs.

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Biphasic voltage‐dependent inactivation of human NaV1.3, 1.6 and 1.7 Na+ channels expressed in rodent insulin‐secreting cells.

• Authors : Godazgar, Mahdieh¹; Zhang, Quan¹; Chibalina, Margarita V.¹

Subjects: *BIPHASIC insulin; *ION channels; *SECRETION

• Source: Journal of Physiology. May2018, Vol. 596 Issue 9, p1601-1626. 26p.

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Dynamin deficiency causes insulin secretion failure and hyperglycemia.

• Authors : Fan Fan; Yumei Wu; Hara, Manami

Subjects: SECRETION; INSULIN; PANCREATIC beta cells

• Source: Proceedings of the National Academy of Sciences of the United States of America; 8/10/2021, Vol. 118 Issue 32, p1-12, 12p

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New Findings from Peking University in the Area of Exocytosis Described (Readily Releasable B Cells With Tight Ca2+-exocytosis Coupling Dictate Biphasic Glucose-stimulated Insulin Secretion).

Subjects: BIPHASIC insulin; B cells; EXOCYTOSIS

• Source: Health & Medicine Week; 5/31/2024, p2527-2527, 1p

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In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse.

• Authors : Henquin, Jean-Claude; Nenquin, Myriam; Stiernet, Patrick

Subjects: SECRETION; INSULIN; HYPERGLYCEMIA

• Source: Diabetes; Feb2006, Vol. 55 Issue 2, p441-451, 11p, 1 Chart, 6 Graphs

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