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Academic Journal

Loading and Sustained Release of Pralidoxime Chloride from Swellable MIL-88B(Fe) and Its Therapeutic Performance on Mice Poisoned by Neurotoxic Agents.

  • Authors : Zhao D; State Key Laboratory of Chemical Resource Engineering, Institute of Chemistry, Beijing University of Chemical Technology, Beijing 100029, P. R. China.; Liu J

Subjects: Metal-Organic Frameworks/Metal-Organic Frameworks/Metal-Organic Frameworks/*chemistry ; Nerve Agents/Nerve Agents/Nerve Agents/*pharmacology ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacology

  • Source: Inorganic chemistry [Inorg Chem] 2022 Jan 24; Vol. 61 (3), pp. 1512-1520. Date of Electronic Publication: 2021 Dec 30.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs.

  • Authors : Shih TM; Medical Toxicology Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA. Electronic address: .; Oyler BL

Subjects: Sarin*; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Antidotes/Antidotes/Antidotes/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 15; Vol. 415, pp. 115443. Date of Electronic Publication: 2021 Feb 04.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comparative evaluation of antidotal efficacy of 2-PAM and HNK-102 oximes during inhalation of sarin vapor in Swiss albino mice.

  • Authors : Swami D; a Pharmacology and Toxicology Division , Defence Research & Development Establishment , Gwalior , India.; Yadav R

Subjects: Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*poisoning ; Inhalation Exposure/Inhalation Exposure/Inhalation Exposure/*adverse effects ; Oximes/Oximes/Oximes/*pharmacology

  • Source: Inhalation toxicology [Inhal Toxicol] 2018 Jun - Jul; Vol. 30 (7-8), pp. 287-298. Date of Electronic Publication: 2018 Oct 30.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8910739 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

No promising antidote 25 years after the Tokyo subway sarin attack: A review.

  • Authors : Sakurada K; Department of Forensic Dentistry, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address: .; Ohta H

Subjects: Antidotes* ; Chemical Terrorism*/Chemical Terrorism*/Chemical Terrorism*/prevention & control ; Drug Development*/Drug Development*/Drug Development*/trends

  • Source: Legal medicine (Tokyo, Japan) [Leg Med (Tokyo)] 2020 Nov; Vol. 47, pp. 101761. Date of Electronic Publication: 2020 Jul 15.Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 100889186 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.

  • Authors : Chambers JE; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi.; Meek EC

Subjects: Antidotes/Antidotes/Antidotes/*therapeutic use ; Nerve Agents/Nerve Agents/Nerve Agents/*toxicity ; Neuroprotection/Neuroprotection/Neuroprotection/*drug effects

  • Source: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2020 Nov; Vol. 1479 (1), pp. 5-12. Date of Electronic Publication: 2020 Apr 21.Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A systems dynamics approach to the efficacy of oxime therapy for mild exposure to sarin gas.

  • Authors : Droste DJ; Environmental Compliance Officer, Marine Corps Installation Command, 3000 Marine Corps, Pentagon, Washington, District of Columbia.; Shelley ML

Subjects: Antidotes/Antidotes/Antidotes/*pharmacokinetics ; Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*pharmacokinetics ; Organophosphate Poisoning/Organophosphate Poisoning/Organophosphate Poisoning/*drug therapy

  • Source: American journal of disaster medicine [Am J Disaster Med] 2016 Spring; Vol. 11 (2), pp. 89-118.Publisher: Prime National Pub. Corp Country of Publication: United States NLM ID: 101291100 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.

  • Authors : Shih TM; Pharmacology Branch, Research Division, U.S. Army Medical Research Institute of Chemical Defense, ATTN: MCMR-CDR-P, Aberdeen Proving Ground, MD 21010-5400, USA. ; Skovira JW

Subjects: Brain/Brain/Brain/*drug effects ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology ; Oximes/Oximes/Oximes/*pharmacology

  • Source: Journal of molecular neuroscience : MN [J Mol Neurosci] 2010 Jan; Vol. 40 (1-2), pp. 63-9. Date of Electronic Publication: 2009 Aug 13.Publisher: Humana Press Country of Publication: United States NLM ID: 9002991 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures.

  • Authors : Spradling KD; Cell and Molecular Biology Branch, US Army Medical Research Institute of Chemical Defense (USAMRICD), 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400, USA.; Lumley LA

Subjects: Brain/Brain/Brain/*drug effects ; Brain/Brain/Brain/*physiology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2011 Jul 21; Vol. 8, pp. 83. Date of Electronic Publication: 2011 Jul 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.

  • Authors : Shih TM; Research and Analytical Toxicology Divisions, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA.; Guarisco JA

Subjects: Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology ; Organophosphorus Compounds/Organophosphorus Compounds/Organophosphorus Compounds/*toxicity ; Organothiophosphorus Compounds/Organothiophosphorus Compounds/Organothiophosphorus Compounds/*toxicity

  • Source: Toxicology mechanisms and methods [Toxicol Mech Methods] 2011 Jan; Vol. 21 (1), pp. 53-62. Date of Electronic Publication: 2010 Nov 30.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In vitro evaluation of bis-pyridinium oximes bearing methoxy alkane linker as reactivators of sarin inhibited human acetylcholinesterase.

  • Authors : Acharya J; Process Technology Development Division, Defence Research and Development Establishment, Gwalior, India. ; Dubey DK

Subjects: Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*toxicity ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology

  • Source: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2010 Sep; Vol. 24 (6), pp. 1797-802. Date of Electronic Publication: 2010 Jun Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  42 results for ""Pralidoxime Compounds""