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Academic Journal

Loading and Sustained Release of Pralidoxime Chloride from Swellable MIL-88B(Fe) and Its Therapeutic Performance on Mice Poisoned by Neurotoxic Agents.

  • Authors : Zhao D; State Key Laboratory of Chemical Resource Engineering, Institute of Chemistry, Beijing University of Chemical Technology, Beijing 100029, P. R. China.; Liu J

Subjects: Metal-Organic Frameworks/Metal-Organic Frameworks/Metal-Organic Frameworks/*chemistry ; Nerve Agents/Nerve Agents/Nerve Agents/*pharmacology ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacology

  • Source: Inorganic chemistry [Inorg Chem] 2022 Jan 24; Vol. 61 (3), pp. 1512-1520. Date of Electronic Publication: 2021 Dec 30.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Comparative evaluation of antidotal efficacy of 2-PAM and HNK-102 oximes during inhalation of sarin vapor in Swiss albino mice.

  • Authors : Swami D; a Pharmacology and Toxicology Division , Defence Research & Development Establishment , Gwalior , India.; Yadav R

Subjects: Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*poisoning ; Inhalation Exposure/Inhalation Exposure/Inhalation Exposure/*adverse effects ; Oximes/Oximes/Oximes/*pharmacology

  • Source: Inhalation toxicology [Inhal Toxicol] 2018 Jun - Jul; Vol. 30 (7-8), pp. 287-298. Date of Electronic Publication: 2018 Oct 30.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8910739 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.

  • Authors : Chambers JE; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi.; Meek EC

Subjects: Antidotes/Antidotes/Antidotes/*therapeutic use ; Nerve Agents/Nerve Agents/Nerve Agents/*toxicity ; Neuroprotection/Neuroprotection/Neuroprotection/*drug effects

  • Source: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2020 Nov; Vol. 1479 (1), pp. 5-12. Date of Electronic Publication: 2020 Apr 21.Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.

  • Authors : Shih TM; Research and Analytical Toxicology Divisions, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA.; Guarisco JA

Subjects: Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology ; Organophosphorus Compounds/Organophosphorus Compounds/Organophosphorus Compounds/*toxicity ; Organothiophosphorus Compounds/Organothiophosphorus Compounds/Organothiophosphorus Compounds/*toxicity

  • Source: Toxicology mechanisms and methods [Toxicol Mech Methods] 2011 Jan; Vol. 21 (1), pp. 53-62. Date of Electronic Publication: 2010 Nov 30.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In vitro evaluation of bis-pyridinium oximes bearing methoxy alkane linker as reactivators of sarin inhibited human acetylcholinesterase.

  • Authors : Acharya J; Process Technology Development Division, Defence Research and Development Establishment, Gwalior, India. ; Dubey DK

Subjects: Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*toxicity ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology

  • Source: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2010 Sep; Vol. 24 (6), pp. 1797-802. Date of Electronic Publication: 2010 Jun Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain.

  • Authors : Kuca K; Department of Toxicology, Faculty of Military Health Sciences, PO Box 35/T, 500 01, Hradec Králové, Czech Republic.; Cabal J

Subjects: Brain/Brain/Brain/*enzymology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology

  • Source: Journal of applied toxicology : JAT [J Appl Toxicol] 2005 Jul-Aug; Vol. 25 (4), pp. 271-6.Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print Cited Medium: Print ISSN: 0260-437X

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Academic Journal

Protection and inflammatory markers following exposure of guinea pigs to sarin vapour: comparative efficacy of three oximes.

  • Authors : Levy A; Israel Institute for Biological Research, Department of Pharmacology, PO Box 19, Ness Ziona 74100, Israel. ; Chapman S

Subjects: Inhalation Exposure*; Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*toxicity ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology

  • Source: Journal of applied toxicology : JAT [J Appl Toxicol] 2004 Nov-Dec; Vol. 24 (6), pp. 501-4.Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print Cited Medium: Print ISSN: 0260-437X

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Academic Journal

[In vitro reactivation of acetylcholinesterase inhibition by O-isopropylmethylfluorophosphonate using the bisquarternary oxime, HS-6].

  • Authors : Kuca K; Katedra toxikologie Vojenské lékarské akademie Jana Evangelisty Purkynĕ, Hradec Králové. ; Cabal J

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Enzyme Activators/Enzyme Activators/Enzyme Activators/*pharmacology

  • Source: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti [Ceska Slov Farm] 2004 Mar; Vol. 53 (2), pp. 93-5.Publisher: Ceská lékarská spolecnost J. E. Purkyne Country of Publication: Czech Republic NLM ID: 9433765 Publication Model: Print Cited Medium:

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Editorial & Opinion

Treatment of sarin exposure.

Subjects: Antidotes/Antidotes/Antidotes/*therapeutic use ; Chemical Warfare Agents/Chemical Warfare Agents/Chemical Warfare Agents/*poisoning ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*poisoning

  • Source: JAMA [JAMA] 2004 Jan 14; Vol. 291 (2), pp. 182; author reply 182-3.Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Evaluation of combined toxic effects of GB/GF and efficacy of jielin injection against combined poisoning in mice.

  • Authors : Luo C; Institute of Pharmacology and Toxicology, Beijing, People's Republic of China. Dr. Chunyuan ; Liang J

Subjects: Antidotes/Antidotes/Antidotes/*therapeutic use ; Atropine/Atropine/Atropine/*administration & dosage ; Benactyzine/Benactyzine/Benactyzine/*administration & dosage

  • Source: Toxicology letters [Toxicol Lett] 1997 Aug 22; Vol. 92 (3), pp. 195-200.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print Cited Medium: Print ISSN: 0378-4274 (Print)

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  • 1-10 of  42 results for ""Pralidoxime Compounds""