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Academic Journal

Population and family studies of dihydropyrimidinuria: prevalence, inheritance mode, and risk of fluorouracil toxicity.

  • Authors : Sumi S; Department of Pediatrics, Nagoya City University Medical School, Nagoya, Japan.; Imaeda M

Subjects: Genes, Recessive*; Amidohydrolases/Amidohydrolases/Amidohydrolases/*deficiency ; Fluorouracil/Fluorouracil/Fluorouracil/*adverse effects

  • Source: American journal of medical genetics [Am J Med Genet] 1998 Jul 24; Vol. 78 (4), pp. 336-40.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7708900 Publication Model: Print Cited Medium: Print ISSN: 0148-7299 (Print)

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Academic Journal

Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity.

Subjects: Fluorouracil/Fluorouracil/Fluorouracil/*adverse effects ; Purine-Pyrimidine Metabolism, Inborn Errors/Purine-Pyrimidine Metabolism, Inborn Errors/Purine-Pyrimidine Metabolism, Inborn Errors/*metabolism ; Pyrimidines/Pyrimidines/Pyrimidines/*metabolism

  • Source: The New England journal of medicine [N Engl J Med] 1985 Jul 25; Vol. 313 (4), pp. 245-9.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Implementation of pharmacogenetic testing in oncology: DPYD-guided dosing to prevent fluoropyrimidine toxicity in British Columbia.

Subjects: DIHYDROPYRIMIDINE dehydrogenase; GENETIC variation; PYRIMIDINESBRITISH Columbia; VANCOUVER (B.C.)

  • Source: Frontiers in Pharmacology; 2023, p1-12, 12p

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Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases.

Subjects: PURINES; BRAIN diseases; PYRIMIDINES

  • Source: Frontiers in Pharmacology; 12/19/2017, p1-18, 18p

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Academic Journal

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity.

Subjects: *FLUOROURACIL; *PYRIMIDINES; *DEHYDROGENASES

  • Source: British Journal of Cancer. 2/1/99, Vol. 79 Issue 3/4, p627. 4p.

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Academic Journal

ss-Alanine and ss-Aminoisobutyric Acid Levels in Two Siblings With Dihydropyrimidinase Deficiency.

Subjects: DIHYDROPYRIDINE; PYRIMIDINES; HETEROCYCLIC compounds

  • Source: Nucleosides, Nucleotides & Nucleic Acids; Jun/Jul2008, Vol. 27 Issue 6/7, p825-829, 5p, 1 Diagram, 1 Chart

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Academic Journal

Dihydropyrimidine Dehydrogenase Activity during Long-Term Adjuvant Treatment with Oral Uracil and Tegafur for Colorectal Cancer.

Subjects: DEHYDROGENASES; FLUOROURACIL; ENZYMES

  • Source: Chemotherapy (0009-3157); 2007, Vol. 53 Issue 6, p442-445, 4p, 1 Chart, 1 Graph

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Academic Journal

Physiologically based pharmacokinetic modelling of the three-step metabolism of pyrimidine using 13C-uracil as an in vivo probe.

Subjects: PYRIMIDINES; PHARMACOKINETICS; ALANINE

  • Source: British Journal of Clinical Pharmacology; Dec2005, Vol. 60 Issue 6, p584-593, 10p, 5 Charts, 6 Graphs

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Academic Journal

Pharmacogénétique du métabolisme des pyrimidines. La dihydropyrimidine déshydrogénase.

Subjects: ANTINEOPLASTIC agents; THERAPEUTICS; DEHYDROGENASES

  • Source: Oncologie (Tech Science Press); mar2005, Vol. 7 Issue 1, p33-39, 7p, 4 Diagrams

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Academic Journal

Pyrimidine Degradation Defects and Severe 5-Fluorouracil Toxicity.

Subjects: PYRIMIDINES; FLUOROURACIL; DEHYDROGENASES

  • Source: Nucleosides, Nucleotides & Nucleic Acids; Aug2004, Vol. 23 Issue 8/9, p1371-1375, 5p, 2 Diagrams

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  • 1-10 of  20 results for ""Fluorouracil toxicity""