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Academic Journal

Piperidine-Mediated [3 + 3] Cyclization of 2-Amino-4 H -chromen-4-ones and 2-Benzylidenemalononitriles: To Access 2-Aminochromeno[2,3- b ]pyridine Derivatives.

  • Authors : Zhang D; School of Chemistry and Chemical Engineering, Yangzhou University,180 Siwangting Street, Yangzhou 225002, P. R. China.; Luo N

Subjects: Piperidines* ; Pyridines*; Cyclization

  • Source: The Journal of organic chemistry [J Org Chem] 2021 Jul 02; Vol. 86 (13), pp. 9218-9224. Date of Electronic Publication: 2021 Jun 23.Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Piperidine and octahydropyrano[3,4-c] pyridine scaffolds for drug-like molecular libraries of the European Lead Factory.

  • Authors : Narhe BD; Leiden Institute of Chemistry, Gorlaeus Laboratories, P. O. Box 9502, Universiteit Leiden, 2300 RA Leiden, The Netherlands.; Breman AC

Subjects: Piperidines/Piperidines/Piperidines/*chemistry ; Pyridines/Pyridines/Pyridines/*chemistry ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2017 Oct 01; Vol. 25 (19), pp. 5160-5170. Date of Electronic Publication: 2017 Jul 10.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evidence for cytochrome P450 3A4-mediated metabolic activation of SCO-267.

  • Authors : Li C; Department of Pharmacy, Henan Province Hospital of Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan Province, China.; Li X

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism ; Piperidines*

  • Source: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2024 Feb; Vol. 45 (1), pp. 30-42. Date of Electronic Publication: 2024 Jan 18.Publisher: Wiley Country of Publication: England NLM ID: 7911226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-081X

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Academic Journal

Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model.

  • Authors : Lee JH; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST), Hwarangro 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Chemistry, Korea University, Anam-ro 145, Seongbuk-gu, Seoul 136-701, Republic of Korea.

Subjects: Analgesics/Analgesics/Analgesics/*pharmacology ; Calcium Channel Blockers/Calcium Channel Blockers/Calcium Channel Blockers/*pharmacology ; Calcium Channels, T-Type/Calcium Channels, T-Type/Calcium Channels, T-Type/*drug effects

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2014 Mar 03; Vol. 74, pp. 246-57. Date of Electronic Publication: 2014 Jan 08.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Discovery of piperidine-linked pyridine analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

  • Authors : Chen X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Ji'nan, Shandong, P.R. China.; Li Y

Subjects: Drug Discovery*; Anti-HIV Agents/Anti-HIV Agents/Anti-HIV Agents/*pharmacology ; HIV Reverse Transcriptase/HIV Reverse Transcriptase/HIV Reverse Transcriptase/*antagonists & inhibitors

  • Source: ChemMedChem [ChemMedChem] 2013 Jul; Vol. 8 (7), pp. 1117-26. Date of Electronic Publication: 2013 May 03.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187

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Academic Journal

Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)].

  • Authors : Westendorf AF; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, University of Greifswald, Greifswald, Germany.; Zerzankova L

Subjects: Cross-Linking Reagents/Cross-Linking Reagents/Cross-Linking Reagents/*chemistry ; DNA/DNA/DNA/*chemistry ; Organoplatinum Compounds/Organoplatinum Compounds/Organoplatinum Compounds/*chemistry

  • Source: Journal of inorganic biochemistry [J Inorg Biochem] 2011 May; Vol. 105 (5), pp. 652-62. Date of Electronic Publication: 2011 Jan 21.Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

II. SAR studies of pyridyl-piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists.

Subjects: Piperazines/Piperazines/Piperazines/*chemical synthesis ; Piperidines/Piperidines/Piperidines/*chemical synthesis ; Pyridines/Pyridines/Pyridines/*chemical synthesis

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Mar 01; Vol. 21 (5), pp. 1527-31. Date of Electronic Publication: 2010 Dec 28.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.

  • Authors : Molinaro C; Department of Process Research, Merck, 16711 Autoroute Transcanadienne, Kirkland, Québec, Canada H9H 3L1. ; Shultz S

Subjects: Cresols/Cresols/Cresols/*chemistry ; Cyclopropanes/Cyclopropanes/Cyclopropanes/*antagonists & inhibitors ; Cyclopropanes/Cyclopropanes/Cyclopropanes/*chemical synthesis

  • Source: The Journal of organic chemistry [J Org Chem] 2011 Feb 18; Vol. 76 (4), pp. 1062-71. Date of Electronic Publication: 2011 Jan 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Association constants of pyridine and piperidine alkaloids to amyloid beta peptide determined by electrochemical impedance spectroscopy.

  • Authors : Grabowska I; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.; Radecka H

Subjects: Alkaloids/Alkaloids/Alkaloids/*chemistry ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*chemistry ; Peptide Fragments/Peptide Fragments/Peptide Fragments/*chemistry

  • Source: Current Alzheimer research [Curr Alzheimer Res] 2010 Mar; Vol. 7 (2), pp. 165-72.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208441 Publication Model: Print Cited Medium: Internet

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Academic Journal

Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora.

  • Authors : Kesting JR; Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.; Tolderlund IL

Subjects: Alkaloids/Alkaloids/Alkaloids/*isolation & purification ; Campanulaceae/Campanulaceae/Campanulaceae/*chemistry ; Lobelia/Lobelia/Lobelia/*chemistry

  • Source: Journal of natural products [J Nat Prod] 2009 Feb 27; Vol. 72 (2), pp. 312-5.Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print Cited Medium: Internet

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  • 1-10 of  1,145 results for ""PIPERIDINE""