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  • 1-10 of  1,069 results for ""Cyclooxygenase 2 Inhibitors""
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Academic Journal

1,5- diaryl pyrazole-loaded chitosan nanoparticles as COX-2 inhibitors, mitigate neoplastic growth by regulating NF-κB pathway in-vivo zebrafish model.

  • Authors : Murugan R; Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, Tamil Nadu, India.; Selvam M

Subjects: Zebrafish* ; Pyrazoles*/Pyrazoles*/Pyrazoles*/chemistry ; Pyrazoles*/Pyrazoles*/Pyrazoles*/pharmacology

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Dec; Vol. 283 (Pt 1), pp. 137599. Date of Electronic Publication: 2024 Nov 13.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study.

  • Authors : Fadaly WAA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.; Elshewy A

Subjects: PPAR gamma*/PPAR gamma*/PPAR gamma*/metabolism ; alpha-Glucosidases*/alpha-Glucosidases*/alpha-Glucosidases*/metabolism ; alpha-Amylases*/alpha-Amylases*/alpha-Amylases*/antagonists & inhibitors

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Nov; Vol. 152, pp. 107760. Date of Electronic Publication: 2024 Aug 25.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme-1/cyclooxygenase-2 inhibitors: Design, synthesis, anti-hypertensive, anti-fibrotic, and anti-inflammatory.

  • Authors : Fadaly WAA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.; Elshaier YAMM

Subjects: Pyrazoles*/Pyrazoles*/Pyrazoles*/pharmacology ; Pyrazoles*/Pyrazoles*/Pyrazoles*/chemistry ; Antihypertensive Agents*/Antihypertensive Agents*/Antihypertensive Agents*/pharmacology

  • Source: Drug development research [Drug Dev Res] 2024 Jun; Vol. 85 (4), pp. e22217.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299

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Academic Journal

Towards targeting EGFR and COX-2 inhibitors: comprehensive computational studies on the role of chlorine group in novel thienyl-pyrazoline derivative.

  • Authors : Wulan FF; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Wahyuningsih TD

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/antagonists & inhibitors ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/chemistry ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024; Vol. 42 (19), pp. 9857-9872. Date of Electronic Publication: 2023 Aug 29.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.

  • Authors : Amin NH; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt. Electronic address: .; Hamed MIA

Subjects: Drug Design*; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/*pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2021 Nov; Vol. 116, pp. 105394. Date of Electronic Publication: 2021 Sep 30.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies.

  • Authors : Abdellatif KRA; Department of Pharmaceutical Organic Chemistry, Beni-Suef University, Beni-Suef 62514, Egypt. Electronic address: .; Abdelall EKA

Subjects: Drug Design*; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2021 Sep; Vol. 114, pp. 105122. Date of Electronic Publication: 2021 Jun 25.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Celecoxib Analogues for Cancer Treatment: An Update on OSU-03012 and 2,5-Dimethyl-Celecoxib.

  • Authors : Sobolewski C; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.; Legrand N

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Celecoxib/Celecoxib/Celecoxib/*therapeutic use ; Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/*therapeutic use

  • Source: Biomolecules [Biomolecules] 2021 Jul 16; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Long-term safety evaluation of Daxocox ® tablets (enflicoxib) in dogs after weekly oral administrations for seven months.

  • Authors : Homedes J; Ecuphar Veterinaria SLU (Animalcare Group) Avgda, Río de Janeiro 60 - 66 planta 13, 08016, Barcelona, Spain. .; Salichs M

Subjects: Dogs*; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*adverse effects ; Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/*adverse effects

  • Source: BMC veterinary research [BMC Vet Res] 2021 Jun 03; Vol. 17 (1), pp. 205. Date of Electronic Publication: 2021 Jun 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148

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Academic Journal

Synthesis and Biological Evaluation of 1,3,5-Trisubstituted 2-Pyrazolines as Novel Cyclooxygenase-2 Inhibitors with Antiproliferative Activity.

  • Authors : Vahedpour T; Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, 5165665811, Iran.; Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, 5165665811, Iran.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*metabolism ; Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/*pharmacology

  • Source: Chemistry & biodiversity [Chem Biodivers] 2021 Mar; Vol. 18 (3), pp. e2000832. Date of Electronic Publication: 2021 Feb 23.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Design and synthesis of pyrazole-pyrazoline hybrids as cancer-associated selective COX-2 inhibitors.

  • Authors : Akhtar W; Drug Design and Medicinal Chemistry Laboratory, Jamia Hamdard, New Delhi, India.; Marella A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/Cyclooxygenase 2 Inhibitors/*pharmacology ; Neoplasms/Neoplasms/Neoplasms/*drug therapy

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2021 Jan; Vol. 354 (1), pp. e2000116. Date of Electronic Publication: 2020 Oct 04.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  1,069 results for ""Cyclooxygenase 2 Inhibitors""