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Academic Journal

The expression of congenital Shoc2 variants induces AKT-dependent crosstalk activation of the ERK1/2 pathway.

  • Authors : Wilson PG; Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S Limestone St, Lexington, KY 40536, United States.; Abdelmoti L

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Human molecular genetics [Hum Mol Genet] 2024 Sep 03; Vol. 33 (18), pp. 1592-1604.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

DNA Methylation in Recurrent Glioblastomas: Increased TEM8 Expression Activates the Src/PI3K/AKT/GSK-3β/B-Catenin Pathway.

  • Authors : Kundu P; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.; Breast Cancer Now Toby Robins Research Centre, Department of Breast Research, The Institute of Cancer Research, London, U.K.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

  • Source: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2024 Sep-Oct; Vol. 21 (5), pp. 485-501.Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium:

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Academic Journal

Akt is a mediator of artery specification during zebrafish development.

  • Authors : Zhou W; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06511, USA.

Subjects: Zebrafish*/Zebrafish*/Zebrafish*/embryology ; Zebrafish*/Zebrafish*/Zebrafish*/genetics ; Zebrafish*/Zebrafish*/Zebrafish*/metabolism

  • Source: Development (Cambridge, England) [Development] 2024 Sep 01; Vol. 151 (17). Date of Electronic Publication: 2024 Sep 02.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, synthesis and cytotoxic evaluation of new thieno[2,3-d]pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers.

  • Authors : Abd El-Mawgoud HK; Chemistry Department, Faculty of Women for Arts, Science and Education, Ain Shams University, Heliopolis, 11767 Cairo, Egypt. Electronic address: .; AboulMagd AM

Subjects: Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/metabolism ; Pyrimidines*/Pyrimidines*/Pyrimidines*/pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107622. Date of Electronic Publication: 2024 Jul 09.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Delivery of AKT1 phospho-forms to human cells reveals differential substrate selectivity.

  • Authors : Siddika T; Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada.; Shao R

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/genetics; Humans

  • Source: IUBMB life [IUBMB Life] 2024 Sep; Vol. 76 (9), pp. 632-646. Date of Electronic Publication: 2024 May 13.Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706

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Academic Journal

AURKB targets DHX9 to promote hepatocellular carcinoma progression via PI3K/AKT/mTOR pathway.

  • Authors : Zhu G; Department of General Surgery, The First Hospital of Nanchang, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.; Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.

Subjects: Aurora Kinase B*/Aurora Kinase B*/Aurora Kinase B*/metabolism ; Aurora Kinase B*/Aurora Kinase B*/Aurora Kinase B*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology

  • Source: Molecular carcinogenesis [Mol Carcinog] 2024 Sep; Vol. 63 (9), pp. 1814-1826. Date of Electronic Publication: 2024 Jun 14.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel isoniazid-hydrazone derivatives induce cell growth inhibition, cell cycle arrest and apoptosis via mitochondria-dependent caspase activation and PI3K/AKT inhibition.

  • Authors : Rouzi K; Laboratory of Analytical Chemistry and Bromatology, Team of Formulation and Quality Control of Health Products, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.; Altay A

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/antagonists & inhibitors ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107563. Date of Electronic Publication: 2024 Jun 13.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Autophagic degradation of DHCR7 activates AKT3 and promotes sevoflurane-induced hippocampal neuroinflammation in neonatal mice.

  • Authors : Hou Q; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Yuan J

Subjects: Sevoflurane*/Sevoflurane*/Sevoflurane*/pharmacology ; Sevoflurane*/Sevoflurane*/Sevoflurane*/adverse effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Sep; Vol. 222, pp. 304-316. Date of Electronic Publication: 2024 Jun 18.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

BCAT1 alleviates early brain injury by inhibiting ferroptosis through PI3K/AKT/mTOR/GPX4 pathway after subarachnoid hemorrhage.

  • Authors : Liu N; Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, China; Key Colleges and Universities Laboratory of Neurosurgery in Heilongjiang Province, Harbin, China

Subjects: Brain Injuries*/Brain Injuries*/Brain Injuries*/metabolism ; Brain Injuries*/Brain Injuries*/Brain Injuries*/pathology ; Brain Injuries*/Brain Injuries*/Brain Injuries*/drug therapy

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Sep; Vol. 222, pp. 173-186. Date of Electronic Publication: 2024 Jun 11.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes.

  • Authors : Mahmud J; Department of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.; Geiler BW

Subjects: Cytomegalovirus*/Cytomegalovirus*/Cytomegalovirus*/physiology ; Cytomegalovirus*/Cytomegalovirus*/Cytomegalovirus*/genetics ; Cytomegalovirus*/Cytomegalovirus*/Cytomegalovirus*/metabolism

  • Source: Science signaling [Sci Signal] 2024 Aug 27; Vol. 17 (851), pp. eadn8727. Date of Electronic Publication: 2024 Aug 27.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic

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  • 1-10 of  19,806 results for ""Proto-Oncogene Proteins c-akt""