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Subject : proteins

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Academic Journal

Interleukin-2 superkines by computational design.

Authors : Ren J; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.; HHMI, Stanford University School of Medicine, Stanford, CA 94305.

Subjects: Interleukin-2*/Interleukin-2*/Interleukin-2*/genetics ; Proteins*/Proteins*/Proteins*/metabolism; Computational Biology/Computational Biology/Computational Biology/methods

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 22; Vol. 119 (12), pp. e2117401119. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

PEGylation Strategy for Improving the Pharmacokinetic and Antitumoral Activity of the IL-2 No-alpha Mutein.

Authors : Díaz-Hernández M; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba.; Chang-Calderón J

Subjects: Interleukin-2* ; Proteins*; Humans

Source: Current pharmaceutical design [Curr Pharm Des] 2023; Vol. 29 (44), pp. 3579-3588.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet

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Academic Journal

Transcriptome-wide stability analysis uncovers LARP4-mediated NFκB1 mRNA stabilization during T cell activation.

Authors : Tian Y; Department of Physics, George Washington University, Washington, DC 20052, USA.; Systems Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Subjects: Interferon-gamma/Interferon-gamma/Interferon-gamma/*genetics ; Interleukin-2/Interleukin-2/Interleukin-2/*genetics ; Proteins/Proteins/Proteins/*genetics

Source: Nucleic acids research [Nucleic Acids Res] 2020 Sep 04; Vol. 48 (15), pp. 8724-8739.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Functional and molecular aspects of transient T cell unresponsiveness: role of selective interleukin-2 deficiency.

Authors : Köller MD; Department Internal Medicine III, Division of Rheumatology, University of Vienna, Austria. ; Kiener HP

Subjects: Lymphocyte Activation* ; Proteins*; Autoimmune Diseases/Autoimmune Diseases/Autoimmune Diseases/*immunology

Source: Clinical and experimental immunology [Clin Exp Immunol] 2003 May; Vol. 132 (2), pp. 225-31.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print Cited Medium: Print ISSN: 0009-9104

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Academic Journal

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.

Authors : Cohney SJ; DNAX Research Institute, Palo Alto, California 94304, USA.; Sanden D

Subjects: Milk Proteins* ; Repressor Proteins* ; Transcription Factors*

Source: Molecular and cellular biology [Mol Cell Biol] 1999 Jul; Vol. 19 (7), pp. 4980-8.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print Cited Medium: Print ISSN: 0270-7306

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Academic Journal

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Authors : Lécine P; INSERM U119, Marseille, France.; Algarté M

Subjects: Gene Expression Regulation* ; Milk Proteins*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

Source: Molecular and cellular biology [Mol Cell Biol] 1996 Dec; Vol. 16 (12), pp. 6829-40.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print Cited Medium: Print ISSN: 0270-7306

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Academic Journal

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation.

Authors : Ravichandran KS; Division of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115.; Burakoff SJ

Subjects: Adaptor Proteins, Signal Transducing*; Interleukin-2/Interleukin-2/Interleukin-2/*pharmacology ; Proteins/Proteins/Proteins/*metabolism

Source: The Journal of biological chemistry [J Biol Chem] 1994 Jan 21; Vol. 269 (3), pp. 1599-602.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Interaction of bovine uterine luminal protein with interleukin-2 and the interleukin-2 receptor of T lymphocytes.

Authors : Segerson EC; Department of Animal Science, North Carolina A&T State University, Greensboro 27411.; Libby DW

Subjects: Glycoproteins* ; Serpins*; Interleukin-2/Interleukin-2/Interleukin-2/*pharmacology

Source: Biology of reproduction [Biol Reprod] 1990 Oct; Vol. 43 (4), pp. 619-28.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0207224 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Pivotal phase III trial of two dose levels of denileukin diftitox for the treatment of cutaneous T-cell lymphoma.

Authors : Olsen E; Duke University Medical Center, Durham, NC 27710, USA. ; Duvic M

Subjects: Diphtheria Toxin* ; Interleukin-2*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2001 Jan 15; Vol. 19 (2), pp. 376-88.Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print Cited Medium: Print

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Academic Journal

Effects of macrophage colony-stimulating factor and interleukin-2 administration on NK1.1(+) cells in mice.

Authors : Misawa E; Biochemical Research Laboratory, Morinaga Milk Industry Co. Ltd., Higashihara 5-1-83, 228-8583, Zama, Kanagawa, Japan. ; Sakurai T

Subjects: Antigens/Antigens/Antigens/*analysis ; Interleukin-2/Interleukin-2/Interleukin-2/*pharmacology ; Killer Cells, Natural/Killer Cells, Natural/Killer Cells, Natural/*drug effects

Source: International journal of immunopharmacology [Int J Immunopharmacol] 2000 Nov; Vol. 22 (11), pp. 967-77.Publisher: Elsevier Science Country of Publication: England NLM ID: 7904799 Publication Model: Print Cited Medium: Print ISSN: 0192-0561 (Print)

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