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Academic Journal

Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions.

  • Authors : Coenen DM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40506, USA.

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Blood Platelets/Blood Platelets/Blood Platelets/*drug effects ; Cilostazol/Cilostazol/Cilostazol/*pharmacology

  • Source: Cells [Cells] 2021 Aug 05; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

The synthesis and biological evaluation of nucleobases/tetrazole hybrid compounds: A new class of phosphodiesterase type 3 (PDE3) inhibitors.

  • Authors : Shekouhy M; Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran. Electronic address: .; Karimian S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Nucleotides/Nucleotides/Nucleotides/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jun 15; Vol. 28 (12), pp. 115540. Date of Electronic Publication: 2020 May 05.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A pathophysiological role of PDE3 in allergic airway inflammation.

  • Authors : Beute J; Department of Pulmonary Medicine, Erasmus MC, 's-Gravendijkwal, Rotterdam, Netherlands.; Lukkes M

Subjects: Asthma/Asthma/Asthma/*immunology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Eosinophils/Eosinophils/Eosinophils/*immunology

  • Source: JCI insight [JCI Insight] 2018 Jan 25; Vol. 3 (2). Date of Electronic Publication: 2018 Jan 25 (Print Publication: 2018).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium:

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Academic Journal

Effects of inhibition of phosphodiesterase 3B in pancreatic islets on insulin secretion: a potential link with some stimulatory pathways.

  • Authors : Kilanowska A; Department of Anatomy and Histology, University of Zielona Gora, Zielona Gora, Poland.; Szkudelski T

Subjects: Amrinone/Amrinone/Amrinone/*pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Insulin Secretion/Insulin Secretion/Insulin Secretion/*drug effects

  • Source: Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Jun; Vol. 127 (3), pp. 250-257. Date of Electronic Publication: 2019 Jun 26.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9510153 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms.

  • Authors : Choi HI; Laboratory of Cutaneous Aging and Hair Research, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Human Environment Interface Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Subjects: Alopecia/Alopecia/Alopecia/*drug therapy ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Hair Follicle/Hair Follicle/Hair Follicle/*drug effects

  • Source: Journal of dermatological science [J Dermatol Sci] 2018 Jul; Vol. 91 (1), pp. 60-68. Date of Electronic Publication: 2018 Apr 11.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9011485 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In Vitro Inhibition of Phosphodiesterase 3B (PDE 3B) by Anthocyanin-Rich Fruit Juice Extracts and Selected Anthocyanins.

  • Authors : Göttel C; Division of Food Chemistry and Toxicology, Department of Chemistry, Technische Universität Kaiserslautern, Erwin-Schrödinger-Straße 52, D-67663 Kaiserslautern, Germany.; Niesen S

Subjects: Anthocyanins*/Anthocyanins*/Anthocyanins*/chemistry ; Anthocyanins*/Anthocyanins*/Anthocyanins*/pharmacology ; Fruit and Vegetable Juices*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 21; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Design and Development of Novel 4-(4-(1H-Tetrazol-5-yl)-1H-pyrazol-1-yl)-6-morpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine as Cardiotonic Agent via Inhibition of PDE3.

  • Authors : Mao ZW; Department of Cardiovasology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, P. R. China.; Li QL

Subjects: Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*chemistry ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/*chemistry

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2016 Apr; Vol. 349 (4), pp. 268-76. Date of Electronic Publication: 2016 Mar 02.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design and discovery of 2-(4-(1H-tetrazol-5-yl)-1H-pyrazol-1-yl)-4-(4-phenyl)thiazole derivatives as cardiotonic agents via inhibition of PDE3.

  • Authors : Duan LM; Department of Geriatric, DaQing Oil Field General Hospital, Da Qing, Heilongjiang 16300, China.; Yu HY

Subjects: Drug Design*; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*chemistry ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2015 Sep 15; Vol. 23 (18), pp. 6111-7. Date of Electronic Publication: 2015 Aug 07.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Repurposing de novo designed entities reveals phosphodiesterase 3B and cathepsin L modulators.

  • Authors : Rodrigues T; Swiss Federal Institute of Technology (ETH), Department of Chemistry and Applied Biosciences, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland. .; Lin YC

Subjects: Cathepsin L/Cathepsin L/Cathepsin L/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/*chemistry

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 May 01; Vol. 51 (35), pp. 7478-81.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Phosphodiesterase-3 inhibitor cilostazol reverses endothelial dysfunction with ageing in rat mesenteric resistance arteries.

  • Authors : Moreira HS; Departamento de Fisiologia e Farmacologia, Centro de Biociências, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rêgo, Cidade Universitária, 50670-901 Recife, Brazil.; Lima-Leal GA

Subjects: Aging/Aging/Aging/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Endothelium, Vascular/Endothelium, Vascular/Endothelium, Vascular/*drug effects

  • Source: European journal of pharmacology [Eur J Pharmacol] 2018 Mar 05; Vol. 822, pp. 59-68. Date of Electronic Publication: 2018 Jan 31.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  59 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""