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Academic Journal

Theoretical Investigations on Free Energy of Binding Cilostazol with Different Cyclodextrins as Complex for Selective PDE3 Inhibition.

  • Authors : Hoelm M; Department of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163/165, 90-236 Lodz, Poland.; Chowdhury N

Subjects: Cilostazol*/Cilostazol*/Cilostazol*/chemistry ; Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/chemistry ; Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 12; Vol. 29 (16). Date of Electronic Publication: 2024 Aug 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions.

  • Authors : Coenen DM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40506, USA.

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Blood Platelets/Blood Platelets/Blood Platelets/*drug effects ; Cilostazol/Cilostazol/Cilostazol/*pharmacology

  • Source: Cells [Cells] 2021 Aug 05; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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The synthesis and biological evaluation of nucleobases/tetrazole hybrid compounds: A new class of phosphodiesterase type 3 (PDE3) inhibitors.

  • Authors : Shekouhy M; Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran. Electronic address: .; Karimian S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Nucleotides/Nucleotides/Nucleotides/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jun 15; Vol. 28 (12), pp. 115540. Date of Electronic Publication: 2020 May 05.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of inhibition of phosphodiesterase 3B in pancreatic islets on insulin secretion: a potential link with some stimulatory pathways.

  • Authors : Kilanowska A; Department of Anatomy and Histology, University of Zielona Gora, Zielona Gora, Poland.; Szkudelski T

Subjects: Amrinone/Amrinone/Amrinone/*pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Insulin Secretion/Insulin Secretion/Insulin Secretion/*drug effects

  • Source: Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Jun; Vol. 127 (3), pp. 250-257. Date of Electronic Publication: 2019 Jun 26.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9510153 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

E-pharmacophore based virtual screening for identification of dual specific PDE5A and PDE3A inhibitors as potential leads against cardiovascular diseases.

  • Authors : Maryam A; Department of Biosciences, COMSATS University, Islamabad, Pakistan.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Biruni University, Istanbul, Turkey.

Subjects: Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/drug therapy ; Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/Phosphodiesterase 3 Inhibitors*/pharmacology; Cyclic Nucleotide Phosphodiesterases, Type 3

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Apr; Vol. 39 (7), pp. 2302-2317. Date of Electronic Publication: 2020 Apr 17.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms.

  • Authors : Choi HI; Laboratory of Cutaneous Aging and Hair Research, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Human Environment Interface Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Subjects: Alopecia/Alopecia/Alopecia/*drug therapy ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Hair Follicle/Hair Follicle/Hair Follicle/*drug effects

  • Source: Journal of dermatological science [J Dermatol Sci] 2018 Jul; Vol. 91 (1), pp. 60-68. Date of Electronic Publication: 2018 Apr 11.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9011485 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.

  • Authors : Turner MJ; Department of Physiology, McGill University, Montreal, Quebec, Canada.; Cystic Fibrosis Translational Research Centre, McGill University, Montreal, Quebec, Canada.

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/*genetics ; Isoquinolines/Isoquinolines/Isoquinolines/*pharmacology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 May 01; Vol. 318 (5), pp. L908-L920. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

In Vitro Inhibition of Phosphodiesterase 3B (PDE 3B) by Anthocyanin-Rich Fruit Juice Extracts and Selected Anthocyanins.

  • Authors : Göttel C; Division of Food Chemistry and Toxicology, Department of Chemistry, Technische Universität Kaiserslautern, Erwin-Schrödinger-Straße 52, D-67663 Kaiserslautern, Germany.; Niesen S

Subjects: Anthocyanins*/Anthocyanins*/Anthocyanins*/chemistry ; Anthocyanins*/Anthocyanins*/Anthocyanins*/pharmacology ; Fruit and Vegetable Juices*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 21; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A pathophysiological role of PDE3 in allergic airway inflammation.

  • Authors : Beute J; Department of Pulmonary Medicine, Erasmus MC, 's-Gravendijkwal, Rotterdam, Netherlands.; Lukkes M

Subjects: Asthma/Asthma/Asthma/*immunology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Eosinophils/Eosinophils/Eosinophils/*immunology

  • Source: JCI insight [JCI Insight] 2018 Jan 25; Vol. 3 (2). Date of Electronic Publication: 2018 Jan 25 (Print Publication: 2018).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium:

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Academic Journal

A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium.

  • Authors : Sucharov CC; Division of Cardiology and Cardiovascular Institute, University of Colorado Denver, Aurora, Colorado. Electronic address: .; Nakano SJ

Subjects: Heart Failure*/Heart Failure*/Heart Failure*/drug therapy ; Heart Failure*/Heart Failure*/Heart Failure*/genetics ; Heart Failure*/Heart Failure*/Heart Failure*/physiopathology

  • Source: Journal of the American College of Cardiology [J Am Coll Cardiol] 2019 Mar 19; Vol. 73 (10), pp. 1173-1184.Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  59 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""