Search Results

Display Settings
Results per page: 10
Sort By: Relevance
Filter
  • 1-10 of  540 results for ""Cytochrome P-450 CYP3A""

Your Filters

Subject : pharmacokinetics
Reset filters
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects.

  • Authors : Cui C; Drug Clinical Trial Center, Peking University Third Hospital, Beijing, 100191, China.; Valerie Sia JE

Subjects: Cytochrome P-450 CYP3A* ; Models, Biological* ; Pharmacokinetics*

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Jul; Vol. 87 (7), pp. 2711-2722. Date of Electronic Publication: 2021 May 18.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs.

  • Authors : Sun H; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.; Piotrowski DW

Subjects: Pharmacokinetics*; Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/*chemistry ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*chemistry

  • Source: PloS one [PLoS One] 2018 Nov 14; Vol. 13 (11), pp. e0206279. Date of Electronic Publication: 2018 Nov 14 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

Record details

Read Online Read More Add to Saved list
×
Academic Journal

Effects of CPY3A5 Genetic Polymorphisms on the Pharmacokinetics of Extendedrelease and Immediate-release Tacrolimus Formulations in Renal Transplant Recipients: A Systematic Review and Meta-analysis.

  • Authors : Xie Q; Department of Pharmacy, Peking University First Hospital, No. 6, Dahongluochang Street, Xicheng District, Beijing 100034, China.; Xiang Q

Subjects: Dosage Forms* ; Pharmacokinetics*; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics

  • Source: Current drug metabolism [Curr Drug Metab] 2021; Vol. 22 (10), pp. 758-771.Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 100960533 Publication Model: Print Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.

  • Authors : Poon KL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore.; Wang X

Subjects: Pharmacokinetics*; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics ; Liver/Liver/Liver/*drug effects

  • Source: Archives of toxicology [Arch Toxicol] 2017 Mar; Vol. 91 (3), pp. 1187-1197. Date of Electronic Publication: 2016 Aug 02.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Physiologically based predictions of the impact of inhibition of intestinal and hepatic metabolism on human pharmacokinetics of CYP3A substrates.

  • Authors : Fenneteau F; Faculté de Pharmacie, Université de Montréal, CP 6128, Succursale Centre Ville, Montréal, Québec, Canada.; Poulin P

Subjects: Cytochrome P-450 CYP3A Inhibitors* ; Models, Biological* ; Pharmacokinetics*

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2010 Jan; Vol. 99 (1), pp. 486-514.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Internet ISSN: 1520-6017

Record details

Read More Add to Saved list
×
Academic Journal

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions.

  • Authors : Wong S; Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA, 94080, United States.; Doshi U

Subjects: Drug Interactions* ; Pharmacokinetics*; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism

  • Source: Drug metabolism letters [Drug Metab Lett] 2018; Vol. 12 (1), pp. 3-13.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101313587 Publication Model: Print Cited Medium: Internet

Record details

Read More Add to Saved list
×
Editorial & Opinion

Preface.

Subjects: Metabolic Clearance Rate* ; Pharmacokinetics*; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism

  • Source: Drug metabolism letters [Drug Metab Lett] 2018; Vol. 12 (1), pp. 2.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101313587 Publication Model: Print Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Strategy for CYP3A Induction Risk Assessment from Preclinical Signal to Human: a Case Example of a Late-Stage Discovery Compound.

  • Authors : Mao J; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, 1 DNA Way, South San Francisco, California, 94080, USA. .; Fan P

Subjects: Computer Simulation* ; Pharmacokinetics*; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*biosynthesis

  • Source: Pharmaceutical research [Pharm Res] 2017 Nov; Vol. 34 (11), pp. 2403-2414. Date of Electronic Publication: 2017 Aug 16.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list
×
Academic Journal

Predicting drug-drug interactions involving the inhibition of intestinal CYP3A4 and P-glycoprotein.

  • Authors : Tachibana T; Pre-clinical Research Department, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.; Kato M

Subjects: Drug Interactions* ; Models, Biological* ; Pharmacokinetics*

  • Source: Current drug metabolism [Curr Drug Metab] 2010 Nov; Vol. 11 (9), pp. 762-77.Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 100960533 Publication Model: Print Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

CYP induction-mediated drug interactions: in vitro assessment and clinical implications.

  • Authors : Lin JH; Department of Preclinical Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania, USA.

Subjects: Drug Interactions* ; Pharmacokinetics* ; Pharmacology*

  • Source: Pharmaceutical research [Pharm Res] 2006 Jun; Vol. 23 (6), pp. 1089-116. Date of Electronic Publication: 2006 May 26.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list
×
  • 1-10 of  540 results for ""Cytochrome P-450 CYP3A""