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Frequency of pharmacogenomic variants affecting safety and efficacy of immunomodulators and biologics in a South Asian population from Sri Lanka.

• Authors : Ranasinghe, Priyanga; Liyanage, Chiranthi; Sirisena, Nirmala

• Source: Human Genomics; 9/27/2024, Vol. 18 Issue 1, p1-13, 13p

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Population distribution of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C risk alleles for methotrexate toxicity in Israel.

• Authors : Efrati, Edna; Elkin, Hela; Nahum, Sagi

Subjects: METHOTREXATE; METHYLENETETRAHYDROFOLATE reductase; OXIDOREDUCTASES

• Source: Rheumatology International; Apr2013, Vol. 33 Issue 4, p1001-1004, 4p, 2 Charts

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Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?

• Authors : Ranganathan, P; Eisen, S; Yokoyama, W M

Subjects: ANTIRHEUMATIC agents; CHRONIC diseases; COMPARATIVE studies

• Source: Annals of the Rheumatic Diseases; Jan2003, p4-9, 6p

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Integration of genomics, clinical characteristics and baseline biological profiles to predict the risk of liver injury induced by high-dose methotrexate.

• Authors : Lin, Chenquan; Ma, Rui; Zeng, Xiao

• Source: Frontiers in Pharmacology; 2024, p1-15, 15p

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Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia.

• Authors : Choi, Jung Yoon; Kwon, Hoshik; Kim, Hyery

Subjects: POLYCYSTIC kidney disease; CHILD patients; LYMPHOBLASTIC leukemia

• Source: Frontiers in Pharmacology; 2024, p1-12, 12p

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Pharmacogenetics and the Blood–Brain Barrier: A Whirlwind Tour of Potential Clinical Utility.

• Authors : Skvarc, David R.; Truong, Trang T. T.; Lundin, Robert M.

Subjects: DRUG discovery; INDIVIDUALIZED medicine; PHARMACOGENOMICS

• Source: Future Pharmacology; Sep2024, Vol. 4 Issue 3, p574-589, 16p

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The 10+1 Santorini Conference.

Subjects: PHARMACOGENOMICS; WEIGHT gain; BLOOD platelet aggregationSANTORINI Island (Greece)

• Source: Clinical Chemistry & Laboratory Medicine; May2024, Vol. 62 Issue 6, peA1-eA43, 43p

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Implementation of pharmacogenetics for treatment of patients with acute lymphoblastic leukemia.

• Authors : Graiqevci-Uka, Violeta; Behluli, Emir; Hadziselimovic, Rifat

Subjects: LYMPHOBLASTIC leukemia treatment; PHARMACOGENOMICS; HUMAN cytogenetics

• Source: Research Results in Pharmacology; 2024, Vol. 10 Issue 2, p27-39, 13p

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Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses.

• Authors : Campbell, Jared; Bateman, Emma; Stephenson, Matthew

Subjects: CANCER treatment; CANCER patients; CANCER chemotherapy

• Source: Cancer Chemotherapy & Pharmacology; Jul2016, Vol. 78 Issue 1, p27-39, 13p

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Association between genetic variants of membrane transporters and the risk of high-grade hematologic adverse events in a cohort of Mexican children with B-cell acute lymphoblastic leukemia.

• Authors : Escalante-Bautista, Deyanira; Cerecedo, Doris; Jiménez-Hernández, Elva

Subjects: MEMBRANE transport proteins; GENETIC variation; LYMPHOBLASTIC leukemia

• Source: Frontiers in Oncology; 2024, p01-10, 10p

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