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Academic Journal

CD8 T cell-derived perforin regulates macrophage-mediated inflammation in a murine model of gout.

  • Authors : Wang T; Department of Rheumatology and Immunology, Beijing Friendship Hospital, Capital Medical University, 95th, Yongan Road, Beijing, 100050, China.; Zhang C

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; Macrophages*/Macrophages*/Macrophages*/metabolism ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: Clinical rheumatology [Clin Rheumatol] 2024 Jun; Vol. 43 (6), pp. 2027-2034. Date of Electronic Publication: 2024 Apr 16.Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949

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Academic Journal

Perforin 1 in Cancer: Mechanisms, Therapy, and Outlook.

  • Authors : Guan X; Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan 030001, China.; Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan 030001, China.

Subjects: Perforin*/Perforin*/Perforin*/metabolism ; Perforin*/Perforin*/Perforin*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/therapy

  • Source: Biomolecules [Biomolecules] 2024 Jul 26; Vol. 14 (8). Date of Electronic Publication: 2024 Jul 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Identification and functional analysis of perforin 1 from largemouth bass (Micropterus salmoides).

  • Authors : Hu X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315211, China; Laboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo, 315211, China

Subjects: Bass*/Bass*/Bass*/immunology ; Bass*/Bass*/Bass*/genetics ; Fish Diseases*/Fish Diseases*/Fish Diseases*/immunology Nocardia seriolae

  • Source: Fish & shellfish immunology [Fish Shellfish Immunol] 2024 Jun; Vol. 149, pp. 109531. Date of Electronic Publication: 2024 Apr 09.Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Reassessing granzyme B: unveiling perforin-independent versatility in immune responses and therapeutic potentials.

  • Authors : Thompson R; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland Baltimore School of Medicine, Baltimore, MD, United States.; Cao X

Subjects: Granzymes*/Granzymes*/Granzymes*/metabolism ; Perforin*/Perforin*/Perforin*/metabolism ; T-Lymphocytes, Cytotoxic*/T-Lymphocytes, Cytotoxic*/T-Lymphocytes, Cytotoxic*/immunology

  • Source: Frontiers in immunology [Front Immunol] 2024 May 23; Vol. 15, pp. 1392535. Date of Electronic Publication: 2024 May 23 (Print Publication: 2024).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Sea Anemone Membrane Attack Complex/Perforin Superfamily Demonstrates an Evolutionary Transitional State between Venomous and Developmental Functions.

  • Authors : Surm JM; Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; Landau M

Subjects: Sea Anemones*/Sea Anemones*/Sea Anemones*/genetics ; Evolution, Molecular* ; Perforin*/Perforin*/Perforin*/metabolism

  • Source: Molecular biology and evolution [Mol Biol Evol] 2024 May 03; Vol. 41 (5).Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.

  • Authors : Shi Z; Department of Medical Laboratory, School of Medical Technology, Tianjin Medical University, Tianjin 300203, China; The Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China.

Subjects: Granzymes*/Granzymes*/Granzymes*/metabolism ; Nanocapsules*/Nanocapsules*/Nanocapsules*/chemistry ; Perforin*/Perforin*/Perforin*/metabolism

  • Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 May; Vol. 369, pp. 658-667. Date of Electronic Publication: 2024 Apr 11.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Peroxisome Proliferator-Activated Receptor δ Suppresses the Cytotoxicity of CD8+ T Cells by Inhibiting RelA DNA-Binding Activity.

  • Authors : Cen B; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Wei J

Subjects: Transcription Factor RelA*/Transcription Factor RelA*/Transcription Factor RelA*/metabolism ; Granzymes*/Granzymes*/Granzymes*/metabolism ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology

  • Source: Cancer research communications [Cancer Res Commun] 2024 Oct 01; Vol. 4 (10), pp. 2673-2684.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium:

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Academic Journal

Enrichment of Rare Variants of Hemophagocytic Lymphohistiocytosis Genes in Systemic Juvenile Idiopathic Arthritis.

Subjects: Lymphohistiocytosis, Hemophagocytic*/Lymphohistiocytosis, Hemophagocytic*/Lymphohistiocytosis, Hemophagocytic*/genetics ; Arthritis, Juvenile*/Arthritis, Juvenile*/Arthritis, Juvenile*/genetics ; Qa-SNARE Proteins*/Qa-SNARE Proteins*/Qa-SNARE Proteins*/genetics

  • Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2024 Oct; Vol. 76 (10), pp. 1566-1572. Date of Electronic Publication: 2024 Aug 09.Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

SIT1 identifies circulating hypoactive T cells with elevated cytotoxic molecule secretion in systemic lupus erythematosus patients.

  • Authors : Hasimu A; Department of Clinical Laboratory, Peking University People's Hospital, 11# Xizhimen South Street, Beijing, China.; Bahabayi A

Subjects: CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/immunology ; CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/metabolism ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology

  • Source: Immunologic research [Immunol Res] 2024 Aug; Vol. 72 (4), pp. 754-765. Date of Electronic Publication: 2024 May 01.Publisher: Humana Press Country of Publication: United States NLM ID: 8611087 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The presence of cytotoxic CD4 and exhausted-like CD8+ T-cells is a signature of active tuberculosis.

  • Authors : Flores-Gonzalez J; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 14080. Mexico.; Ramón-Luing LA

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism ; CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/immunology

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Aug; Vol. 1870 (6), pp. 167219. Date of Electronic Publication: 2024 May 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,531 results for ""Perforin""