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Academic Journal

ATXN3: a multifunctional protein involved in the polyglutamine disease spinocerebellar ataxia type 3.

  • Authors : Hernández-Carralero E; Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.

Subjects: Ataxin-3*/Ataxin-3*/Ataxin-3*/metabolism ; Ataxin-3*/Ataxin-3*/Ataxin-3*/genetics ; Machado-Joseph Disease*/Machado-Joseph Disease*/Machado-Joseph Disease*/metabolism

  • Source: Expert reviews in molecular medicine [Expert Rev Mol Med] 2024 Sep 25; Vol. 26, pp. e19. Date of Electronic Publication: 2024 Sep 25.Publisher: Published by Cambridge University Press in association with the Clinical and Biomedical Computing Unit of the University of Cambridge School of Clinical Medicine

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Academic Journal

DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases.

  • Authors : Zhang N; Department of Neurology, Neuroscience Program, Houston Methodist Research Institute, Houston, TX, USA. .; Bewick B

Subjects: DNA, Catalytic/DNA, Catalytic/DNA, Catalytic/*administration & dosage ; DNA, Catalytic/DNA, Catalytic/DNA, Catalytic/*genetics ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*genetics

  • Source: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2021 Jul; Vol. 18 (3), pp. 1710-1728. Date of Electronic Publication: Publisher: Springer Country of Publication: United States NLM ID: 101290381 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Machado-Joseph disease-associated expanded form of ataxin-3: Overexpression, purification, and preliminary biophysical and structural characterization.

Subjects: Ataxin-3/Ataxin-3/Ataxin-3/*chemistry ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*genetics ; Peptides/Peptides/Peptides/*chemistry

  • Source: Protein expression and purification [Protein Expr Purif] 2018 Dec; Vol. 152, pp. 40-45. Date of Electronic Publication: 2018 Jul 20.Publisher: Academic Press Country of Publication: United States NLM ID: 9101496 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3.

  • Authors : Chen ZS; Laboratory of Drosophila Research, School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.; Nexus of Rare Neurodegenerative Diseases, School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

Subjects: Ataxin-3/Ataxin-3/Ataxin-3/*metabolism ; DNA Repair Enzymes/DNA Repair Enzymes/DNA Repair Enzymes/*metabolism ; Drosophila Proteins/Drosophila Proteins/Drosophila Proteins/*metabolism

  • Source: Cell death & disease [Cell Death Dis] 2021 Feb 02; Vol. 12 (2), pp. 136. Date of Electronic Publication: 2021 Feb 02.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pathogenesis of SCA3 and implications for other polyglutamine diseases.

  • Authors : McLoughlin HS; Department of Neurology, University of Michigan, Ann Arbor, MI, USA. Electronic address: .; Moore LR

Subjects: Machado-Joseph Disease* ; Peptides*; Animals

  • Source: Neurobiology of disease [Neurobiol Dis] 2020 Feb; Vol. 134, pp. 104635. Date of Electronic Publication: 2019 Oct 24.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neurodegenerative phosphoprotein signaling landscape in models of SCA3.

  • Authors : Sowa AS; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Calwerstrasse 7, 72076, Tuebingen, Germany.; Centre for Rare Diseases, University of Tuebingen, 72076, Tuebingen, Germany.

Subjects: Ataxin-3/Ataxin-3/Ataxin-3/*physiology ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*physiopathology ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*physiology

  • Source: Molecular brain [Mol Brain] 2021 Mar 19; Vol. 14 (1), pp. 57. Date of Electronic Publication: 2021 Mar 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3.

  • Authors : Koike Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Jansen-West KR

Subjects: Ataxin-3/Ataxin-3/Ataxin-3/*urine ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*urine ; Peptides/Peptides/Peptides/*urine

  • Source: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2021 Aug; Vol. 89, pp. 151-154. Date of Electronic Publication: 2021 Jul 17.Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells.

  • Authors : Ouyang S; Key Laboratory for Major Obstetric Diseases of Guangdong Province, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, The Third Affiliated Hospital of Guangzhou Medical University , Guangzhou City, People's Republic of China .; Xie Y

Subjects: CRISPR-Cas Systems* ; Gene Deletion*; Ataxin-3/Ataxin-3/Ataxin-3/*genetics

  • Source: Stem cells and development [Stem Cells Dev] 2018 Jun 01; Vol. 27 (11), pp. 756-770. Date of Electronic Publication: 2018 May 18.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101197107 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.

  • Authors : Chen IC; Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan.; Chang CN

Subjects: Antioxidants* ; Neuroprotective Agents* ; Phytotherapy*

  • Source: The American journal of Chinese medicine [Am J Chin Med] 2019; Vol. 47 (1), pp. 63-95. Date of Electronic Publication: 2019 Jan 07.Publisher: World Scientific Pub Country of Publication: Singapore NLM ID: 7901431 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation.

  • Authors : Seidel K; Dr. Senckenbergisches Chronomedizinisches Institut, Goethe University, Frankfurt/Main, Germany.; Siswanto S

Subjects: Brain/Brain/Brain/*pathology ; Huntington Disease/Huntington Disease/Huntington Disease/*pathology ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*pathology

  • Source: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2016 Feb; Vol. 42 (2), pp. 153-66. Date of Electronic Publication: 2015 Jul 02.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7609829 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  136 results for ""Machado-Joseph Disease""