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Academic Journal

Small molecule- and peptide-drug conjugates addressing integrins: A story of targeted cancer treatment.

  • Authors : Paulus J; Organic and Bioorganic Chemistry, Faculty of Chemistry, Bielefeld University, Bielefeld, Germany.; Sewald N

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism ; Peptides*/Peptides*/Peptides*/chemistry

  • Source: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2024 Jul; Vol. 30 (7), pp. e3561. Date of Electronic Publication: 2024 Feb 21.Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Expansion and differentiation of human neural stem cells on synthesized integrin binding peptide surfaces.

  • Authors : Jiang C; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan 450052, People's Republic of China.; Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA 23220, United States of America.

Subjects: Neural Stem Cells*/Neural Stem Cells*/Neural Stem Cells*/cytology ; Neural Stem Cells*/Neural Stem Cells*/Neural Stem Cells*/metabolism ; Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/drug effects

  • Source: Biomedical materials (Bristol, England) [Biomed Mater] 2024 Jun 18; Vol. 19 (4). Date of Electronic Publication: 2024 Jun 18.Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8.

  • Authors : Nardelli F; IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy. .; Ghitti M

Subjects: Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*metabolism ; Chromogranin A/Chromogranin A/Chromogranin A/*chemistry ; Integrins/Integrins/Integrins/*metabolism

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2019 Dec 05; Vol. 55 (98), pp. 14777-14780.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.

Subjects: Gastrointestinal Agents*/Gastrointestinal Agents*/Gastrointestinal Agents*/administration & dosage ; Gastrointestinal Agents*/Gastrointestinal Agents*/Gastrointestinal Agents*/adverse effects ; Gastrointestinal Agents*/Gastrointestinal Agents*/Gastrointestinal Agents*/pharmacokinetics

  • Source: Gastroenterology [Gastroenterology] 2021 Dec; Vol. 161 (6), pp. 1853-1864.e10. Date of Electronic Publication: 2021 Aug 30.Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design and Evaluation of a Polypeptide that Mimics the Integrin Binding Site for EDA Fibronectin to Block Profibrotic Cell Activity.

  • Authors : Zhang L; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.; Yan H

Subjects: Drug Design*; Fibroblasts/Fibroblasts/Fibroblasts/*drug effects ; Fibronectins/Fibronectins/Fibronectins/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 04; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Involvement of Integrin-Activating Peptides Derived from Tenascin-C in Cancer Aggression and New Anticancer Strategy Using the Fibronectin-Derived Integrin-Inactivating Peptide.

  • Authors : Fujita M; Department of Molecular Patho-Physiology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.; Sasada M

Subjects: Integrins/Integrins/Integrins/*genetics ; Neoplasms/Neoplasms/Neoplasms/*drug therapy ; Peptides/Peptides/Peptides/*therapeutic use

  • Source: Molecules (Basel, Switzerland) [Molecules] 2020 Jul 16; Vol. 25 (14). Date of Electronic Publication: 2020 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Design and synthesis of a novel peptide for selective detection of cancer cells.

  • Authors : Rajavenkatesh K; Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Chennai, India.; Padmaja M

Subjects: CD13 Antigens/CD13 Antigens/CD13 Antigens/*chemistry ; Flow Cytometry/Flow Cytometry/Flow Cytometry/*methods ; Integrins/Integrins/Integrins/*chemistry

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2020 Jun; Vol. 95 (6), pp. 610-623. Date of Electronic Publication: 2020 Apr 08.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Membrane receptor activation mechanisms and transmembrane peptide tools to elucidate them.

  • Authors : Westerfield JM; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996.; Barrera FN

Subjects: Integrins/Integrins/Integrins/*ultrastructure ; Peptides/Peptides/Peptides/*genetics ; Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Feb 14; Vol. 295 (7), pp. 1792-1814. Date of Electronic Publication: 2019 Dec 25.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

A Peptide Construct Mediates Focal Adhesion Pathway Through the Activation of Integrin Receptor.

  • Authors : Khosravi M; Medicine Biochemistry, Qom Branch, Islamic Azad University, Qom, Iran.; Kakavandi N

Subjects: Focal Adhesions* ; Integrins*; Peptides/Peptides/Peptides/*pharmacology

  • Source: Current pharmaceutical design [Curr Pharm Des] 2020; Vol. 26 (15), pp. 1749-1755.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet

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Academic Journal

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity.

  • Authors : Stefanick JF; Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA. .; Omstead DT

Subjects: Integrin alpha4beta1*/Integrin alpha4beta1*/Integrin alpha4beta1*/antagonists & inhibitors ; Integrin alpha4beta1*/Integrin alpha4beta1*/Integrin alpha4beta1*/metabolism ; Integrins*/Integrins*/Integrins*/antagonists & inhibitors

  • Source: Nanoscale [Nanoscale] 2019 Mar 07; Vol. 11 (10), pp. 4414-4427.Publisher: RSC Pub Country of Publication: England NLM ID: 101525249 Publication Model: Print Cited Medium: Internet ISSN: 2040-3372 (Electronic)

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  • 1-10 of  3,755 results for ""Integrins""