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Academic Journal

Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism.

  • Authors : Varghese S; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia.; Srivastava A

Subjects: Trypanocidal Agents*/Trypanocidal Agents*/Trypanocidal Agents*/chemistry ; Parasites* ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/drug therapy

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 15; Vol. 268, pp. 116162. Date of Electronic Publication: 2024 Jan 17.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code.

Subjects: Parasites*/Parasites*/Parasites*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosomatina*/Trypanosomatina*/Trypanosomatina*/genetics

  • Source: BMC genomics [BMC Genomics] 2024 Feb 16; Vol. 25 (1), pp. 184. Date of Electronic Publication: 2024 Feb 16.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites.

  • Authors : De Niz M; Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Université de Paris, INSERM U1201, Paris, France.; Frachon E

Subjects: Trypanosoma brucei brucei* ; Parasites* ; Trypanosomiasis, African*

  • Source: PloS one [PLoS One] 2023 Dec 22; Vol. 18 (12), pp. e0296257. Date of Electronic Publication: 2023 Dec 22 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

AAK1-like: A putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites.

  • Authors : Black JA; The Wellcome Centre for Integrative Parasitology, School of Infection & Immunity, University of Glasgow, Glasgow, UK.; Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Parasites*/Parasites*/Parasites*/metabolism

  • Source: The Journal of eukaryotic microbiology [J Eukaryot Microbiol] 2023 Nov-Dec; Vol. 70 (6), pp. e12994. Date of Electronic Publication: 2023 Aug 07.Publisher: Wiley Country of Publication: United States NLM ID: 9306405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7408

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Academic Journal

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms.

  • Authors : Reuter C; Department of Cell and Developmental Biology, Biocenter, Julius-Maximilians-Universitaet of Wuerzburg, Wuerzburg, Germany.; Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Wuerzburg, Wuerzburg, Germany.

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Parasites* ; Trypanosoma*

  • Source: Nature communications [Nat Commun] 2023 Nov 23; Vol. 14 (1), pp. 7660. Date of Electronic Publication: 2023 Nov 23.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.

  • Authors : Rajan KS; The Mina and Everard Goodman Faculty of Life Sciences and Advanced and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan, 5290002, Israel.; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, 7610001, Israel.

Subjects: Parasites*/Parasites*/Parasites*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism; Animals

  • Source: Nature communications [Nat Commun] 2023 Nov 20; Vol. 14 (1), pp. 7462. Date of Electronic Publication: 2023 Nov 20.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection.

  • Authors : Sinton MC; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, UK. .; School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK. .

Subjects: Parasites* ; Trypanosoma brucei brucei*; Humans

  • Source: Nature communications [Nat Commun] 2023 Nov 03; Vol. 14 (1), pp. 7070. Date of Electronic Publication: 2023 Nov 03.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and Biophysical and Biological Studies of N -Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.

  • Authors : Nué-Martinez JJ; Instituto de Química Médica, IQM-CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain.; PhD Programme in Medicinal Chemistry, Doctoral School, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain.

Subjects: Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Leishmania donovani*/Leishmania donovani*/Leishmania donovani*/metabolism ; Parasites*/Parasites*/Parasites*/drug effects

  • Source: Journal of medicinal chemistry [J Med Chem] 2023 Oct 12; Vol. 66 (19), pp. 13452-13480. Date of Electronic Publication: 2023 Sep 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

2-Aroyl quinazolinone: Synthesis and in vitro anti-parasitic activity.

  • Authors : Setshedi KJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.; Beteck RM

Subjects: Parasites* ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology ; Trypanosoma brucei brucei*

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2023 Oct; Vol. 102 (4), pp. 763-772. Date of Electronic Publication: 2023 Jun 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comprehensive sub-mitochondrial protein map of the parasitic protist Trypanosoma brucei defines critical features of organellar biology.

  • Authors : Pyrih J; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic; Department of Biochemistry, University of Cambridge, Cambridge, UK

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism ; Parasites*/Parasites*/Parasites*/metabolism; Animals

  • Source: Cell reports [Cell Rep] 2023 Sep 26; Vol. 42 (9), pp. 113083. Date of Electronic Publication: 2023 Sep 04.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  134 results for ""Trypanosoma brucei brucei""