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Academic Journal

Biological impact and therapeutic potential of a novel camptothecin derivative (FLQY2) in pancreatic cancer through inactivation of the PDK1/AKT/mTOR pathway.

  • Authors : Wang W; College of Pharmaceutical Sciences, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Key Laboratory of Marine Fishery Resources Exploitment, Zhejiang Province, China.; Xiong H

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Jul; Vol. 148, pp. 107436. Date of Electronic Publication: 2024 May 08.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

OCIAD2 promotes pancreatic cancer progression through the AKT signaling pathway.

  • Authors : Yin YF; State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, PR China; Department of Biliary-Pancreatic Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, PR China.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Gene [Gene] 2024 Nov 15; Vol. 927, pp. 148735. Date of Electronic Publication: 2024 Jun 27.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic Tumors.

  • Authors : Chen C; Department of Physiology & Biophysics, Stony Brook University, Stony Brook, NY 11794, USA.; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY 11790, USA.

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology

  • Source: Cells [Cells] 2024 Jun 19; Vol. 13 (12). Date of Electronic Publication: 2024 Jun 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.

  • Authors : Song N; Department of Pathology, Xinxiang Key Laboratory of Tumor Precision Medicine, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China; Department of Pathology, Xinxiang Medical University, Xinxiang 453000, China.

Subjects: Calpain*/Calpain*/Calpain*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Journal of proteomics [J Proteomics] 2024 Jun 15; Vol. 301, pp. 105182. Date of Electronic Publication: 2024 Apr 30.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101475056 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways.

  • Authors : Zhao ZX; Department of General Surgery, Qinghai Provincial People's Hospital, Xining 810007, Qinghai Province, China.; Li S

Subjects: Benzoquinones*/Benzoquinones*/Benzoquinones*/pharmacology ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/genetics

  • Source: World journal of gastroenterology [World J Gastroenterol] 2024 Jun 07; Vol. 30 (21), pp. 2793-2816.Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 100883448 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Gap junction beta-4 accelerates cell cycle progression and metastasis through MET-AKT activation in pancreatic cancer.

  • Authors : Muramatsu J; Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Japan.; Arihara Y

Subjects: Cell Proliferation* ; Connexins*/Connexins*/Connexins*/metabolism ; Connexins*/Connexins*/Connexins*/genetics

  • Source: Cancer science [Cancer Sci] 2024 May; Vol. 115 (5), pp. 1564-1575. Date of Electronic Publication: 2024 Feb 11.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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Academic Journal

DTX3L Accelerates Pancreatic cancer Progression via FAK/PI3K/AKT Axis.

  • Authors : Chen L; Department of Hepatobiliary Pancreatic Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, No. 321 Zhongshan Road, Nanjing, 210008, Jiangsu Province, China.; Department of Hepatobiliary Surgery, Nantong First People's Hospital, the Second Affiliated Hospital of Nantong University, #6 Hai'Er Xiang North Road, Nantong, 226001, Jiangsu Province, China.

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics; Humans

  • Source: Biochemical genetics [Biochem Genet] 2024 Apr; Vol. 62 (2), pp. 814-830. Date of Electronic Publication: 2023 Jul 17.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0126611 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

HHLA2 deficiency inhibits pancreatic cancer progression and THP-1 macrophage M2 polarization via EGFR/MAPK/ERK and mTOR/AKT pathway.

  • Authors : Zhou S; Department of Gastroenterology, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, No.321, Zhongshan Road, Nanjing, 210008, China.; Department of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics

  • Source: World journal of surgical oncology [World J Surg Oncol] 2024 May 18; Vol. 22 (1), pp. 133. Date of Electronic Publication: 2024 May 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819

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Academic Journal

CCNI2 promotes pancreatic cancer through PI3K/AKT signaling pathway.

  • Authors : Hu B; Department of Hepatobiliary Surgery, the First Medical Center, Chinese PLA General Hospital, Chinese PLA Medical School, Haidian District, Beijing City, China.; Zhang W

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics; Humans

  • Source: Biomolecules & biomedicine [Biomol Biomed] 2024 Mar 11; Vol. 24 (2), pp. 323-336. Date of Electronic Publication: 2024 Mar 11.Publisher: Association of Basic Medical Sciences of FBIH Country of Publication: Bosnia and Herzegovina NLM ID: 9918522188506676 Publication Model: Electronic

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Academic Journal

The Tanshinones (Tan) Extract From Salvia miltiorrhiza Bunge Induces ROS-Dependent Apoptosis in Pancreatic Cancer via AKT Hyperactivation-Mediated FOXO3/SOD2 Signaling.

  • Authors : Xu Q; The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.; Zhejiang Chinese Medical University, Hangzhou, China.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Salvia miltiorrhiza*/Salvia miltiorrhiza*/Salvia miltiorrhiza*/chemistry ; Abietanes*/Abietanes*/Abietanes*/pharmacology

  • Source: Integrative cancer therapies [Integr Cancer Ther] 2024 Jan-Dec; Vol. 23, pp. 15347354241258961.Publisher: Sage Publications Country of Publication: United States NLM ID: 101128834 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  718 results for ""Proto-Oncogene Proteins c-akt""