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Academic Journal

Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6.

Subjects: OXIMES; ACETYLCHOLINESTERASE; ORGANOPHOSPHORUS compounds

  • Source: Toxicology Mechanisms & Methods. May2009, Vol. 19 Issue 4, p327-333. 7p. 1 Diagram, 4 Charts, 1 Graph.

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Academic Journal

Pharmacokinetic study of two acetylcholinesterase reactivators, trimedoxime and newly synthesized oxime K027, in rat plasma.

Subjects: ACETYLCHOLINESTERASE; PHARMACOKINETICS; MURIDAE

  • Source: Journal of Applied Toxicology; Jan2013, Vol. 33 Issue 1, p18-23, 5p

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Academic Journal

New K-Oximes (K-27 and K-48) in Comparison with Obidoxime (LuH-6), HI-6, Trimedoxime (TMB-4), and Pralidoxime (2-PAM): Survival in Rats Exposed IP to the Organophosphate Paraoxon.

Subjects: OXIMES; CHOLINESTERASES; ORGANOPHOSPHORUS compounds

  • Source: Toxicology Mechanisms & Methods. Sep/Oct2007, Vol. 17 Issue 7, p401-408. 8p. 1 Diagram, 4 Charts.

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Academic Journal

Five oximes (K-27, K-48, obidoxime, Hl-6 and trimedoxime) in comparison with pralidoxime: survival in rats exposed to methyl-paraoxon.

Subjects: OXIMES; ORGANONITROGEN compounds; CHOLINESTERASESUNITED States

  • Source: Journal of Applied Toxicology; Sep/Oct2007, Vol. 27 Issue 5, p453-457, 5p, 1 Chart

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Academic Journal

In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase.

Subjects: ORGANOPHOSPHORUS compounds; PESTICIDES; NERVE gases

  • Source: Clinical Toxicology (15563650). 2009, Vol. 47 Issue 6, p545-550. 6p. 1 Diagram, 2 Charts.

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Academic Journal

Oxime K203: a drug candidate for the treatment of tabun intoxication.

Subjects: TABUN; ACETYLCHOLINESTERASE; ORGANOPHOSPHORUS compounds

  • Source: Archives of Toxicology; Mar2019, Vol. 93 Issue 3, p673-691, 19p, 5 Diagrams, 9 Charts, 4 Graphs

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Academic Journal

Changes of rat plasma total low molecular weight antioxidant level after tabun exposure and consequent treatment by acetylcholinesterase reactivators.

Subjects: MOLECULAR weights; BLOOD plasma; LABORATORY rats

  • Source: Journal of Enzyme Inhibition & Medicinal Chemistry; Feb2011, Vol. 26 Issue 1, p93-97, 5p

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Academic Journal

Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain

Subjects: *OXIMES; *PARTITION coefficient (Chemistry); *CHLOROMETHYL group

  • Source: Journal of Pharmaceutical & Biomedical Analysis. Apr2011, Vol. 54 Issue 5, p1082-1087. 6p.

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Academic Journal

In Vitro Ability of Currently Available Oximes to Reactivate Organophosphate Pesticide-Inhibited Human Acetylcholinesterase and Butyrylcholinesterase.

Subjects: OXIMES; PESTICIDES; ACETYLCHOLINESTERASE

  • Source: International Journal of Molecular Sciences; Mar2011, Vol. 12 Issue 3, p2077-2087, 11p, 1 Diagram, 3 Charts, 5 Graphs

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Academic Journal

In vitro oxime protection of human red blood cell acetyicholinesterase inhibited by diisopropyl- fluorophosphate.

Subjects: ORGANOPHOSPHORUS compounds; PHOSPHORUS compounds; CHLORFENVINPHOS

  • Source: Journal of Applied Toxicology; May2008, Vol. 28 Issue 4, p422-429, 8p, 1 Diagram, 1 Chart, 1 Graph

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  • 1-10 of  82 results for ""Trimedoxime""