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Academic Journal

Alpha-Synuclein Interaction with UBL3 Is Upregulated by Microsomal Glutathione S-Transferase 3, Leading to Increased Extracellular Transport of the Alpha-Synuclein under Oxidative Stress.

  • Authors : Yan J; Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuoka 431-3192, Japan.; Kahyo T

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Oxidative Stress*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 04; Vol. 25 (13). Date of Electronic Publication: 2024 Jul 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Effect of Clemizole on Alpha-Synuclein-Preformed Fibrils-Induced Parkinson's Disease Pathology: A Pharmacological Investigation.

  • Authors : Vaidya B; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education, S.A.S. Nagar, Mohali, Punjab, 160062, India.; Gupta P

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects

  • Source: Neuromolecular medicine [Neuromolecular Med] 2024 May 04; Vol. 26 (1), pp. 19. Date of Electronic Publication: 2024 May 04.Publisher: Humana Press Country of Publication: United States NLM ID: 101135365 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hederagenin inhibits mitochondrial damage in Parkinson's disease via mitophagy induction.

  • Authors : Li X; School of Pharmacy, Department of Pharmacy, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Gui Yang, 550000, China. Electronic address: .; Hu M

Subjects: Mitophagy*/Mitophagy*/Mitophagy*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Nov 01; Vol. 224, pp. 740-756. Date of Electronic Publication: 2024 Sep 21.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evaluation of Neuroprotective Effect of Gut Microbe in Parkinson's Disease: An In Silico and In Vivo Approach.

  • Authors : Bhardwaj K; Department of Zoology, IIS (Deemed to be University), Jaipur, Rajasthan, 302020, India.; Rajawat NK

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/physiology ; Probiotics*/Probiotics*/Probiotics*/therapeutic use ; Probiotics*/Probiotics*/Probiotics*/pharmacology

  • Source: Neuromolecular medicine [Neuromolecular Med] 2024 Aug 01; Vol. 26 (1), pp. 32. Date of Electronic Publication: 2024 Aug 01.Publisher: Humana Press Country of Publication: United States NLM ID: 101135365 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mitochondrial transfer of α-synuclein mediates carbon disulfide-induced mitochondrial dysfunction and neurotoxicity.

  • Authors : Liu Z; Department of Toxicology and Nutrition, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.; Shan S

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; Carbon Disulfide*/Carbon Disulfide*/Carbon Disulfide*/toxicity ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects

  • Source: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Aug; Vol. 281, pp. 116613. Date of Electronic Publication: 2024 Jun 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

2-Butoxytetrahydrofuran, Isolated from Holothuria scabra , Attenuates Aggregative and Oxidative Properties of α-Synuclein and Alleviates Its Toxicity in a Transgenic Caenorhabditis elegans Model of Parkinson's Disease.

  • Authors : Promtang S; Molecular Medicine Program, Multidisciplinary Unit, Faculty of Science, Mahidol University, Ratchathewi, Bangkok 10400, Thailand.; Sanguanphun T

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/drug effects ; Furans*/Furans*/Furans*/pharmacology

  • Source: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Jun 05; Vol. 15 (11), pp. 2182-2197. Date of Electronic Publication: 2024 May 10.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Positron Emission Tomography with [ 18 F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy.

  • Authors : Gallagher E; Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Subjects: Oxidative Stress* ; Synucleinopathies*/Synucleinopathies*/Synucleinopathies*/diagnostic imaging ; Synucleinopathies*/Synucleinopathies*/Synucleinopathies*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 01; Vol. 25 (9). Date of Electronic Publication: 2024 May 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cannabinoid receptor-1 has an effect on CD200 under rotenone and alpha-synuclein induced stress.

  • Authors : Cankara FN; Süleyman Demirel University, Faculty of Medicine, Department of Pharmacology, Isparta, Turkey. Electronic address: .; Çelik ZB

Subjects: Antigens, CD/Antigens, CD/Antigens, CD/*biosynthesis ; Oxidative Stress/Oxidative Stress/Oxidative Stress/*drug effects ; Receptor, Cannabinoid, CB1/Receptor, Cannabinoid, CB1/Receptor, Cannabinoid, CB1/*metabolism

  • Source: Neuroscience letters [Neurosci Lett] 2021 Jun 11; Vol. 755, pp. 135908. Date of Electronic Publication: 2021 Apr 20.Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Oxidative Stress and Mitochondrial Complex I Dysfunction Correlate with Neurodegeneration in an α-Synucleinopathy Animal Model.

  • Authors : Morales-Martínez A; Laboratorio de Neurofarmacología Molecular y Nanotecnología, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City 14269, Mexico.; Laboratorio de Patogenesis Molecular, Laboratorio 4, Edificio A4, Carrera Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Mexico.

Subjects: Brain*/Brain*/Brain*/metabolism ; Brain*/Brain*/Brain*/physiopathology ; Electron Transport Complex I*/Electron Transport Complex I*/Electron Transport Complex I*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 27; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Novel Alpha-Synuclein Oligomers Formed with the Aminochrome-Glutathione Conjugate Are Not Neurotoxic.

  • Authors : Huenchuguala S; Molecular and Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Independencia, 1027, Santiago-7, Chile.; Escuela de Tecnología Médica, Facultad de Salud, Universidad Santo Tomás, Los Carreras, 753, Osorno, Chile.

Subjects: Glutathione/Glutathione/Glutathione/*metabolism ; Indolequinones/Indolequinones/Indolequinones/*metabolism ; Oxidative Stress/Oxidative Stress/Oxidative Stress/*physiology

  • Source: Neurotoxicity research [Neurotox Res] 2019 Feb; Vol. 35 (2), pp. 432-440. Date of Electronic Publication: 2018 Oct 20.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,743 results for ""ALPHA-synuclein""