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Academic Journal

Pralidoxime Is no Longer Fit for Purpose as an Antidote to Organophosphate Poisoning in the United Kingdom.

  • Authors : Corby G; St John's College, University of Oxford, Oxford, UK.

Subjects: Organophosphate Poisoning*/Organophosphate Poisoning*/Organophosphate Poisoning*/drug therapy ; Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/therapeutic use ; Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/pharmacology

  • Source: Disaster medicine and public health preparedness [Disaster Med Public Health Prep] 2024 Feb 22; Vol. 18, pp. e32. Date of Electronic Publication: 2024 Feb 22.Publisher: Cambridge University Press Country of Publication: United States NLM ID: 101297401 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Suspected intermediate syndrome in a dog after organophosphate poisoning.

  • Authors : Schmid RD; Pet Poison Helpline/SafetyCall International, LLC, Bloomington, Minnesota, USA.; Lombardo D

Subjects: Organophosphate Poisoning*/Organophosphate Poisoning*/Organophosphate Poisoning*/drug therapy ; Organophosphate Poisoning*/Organophosphate Poisoning*/Organophosphate Poisoning*/veterinary ; Insecticides*/Insecticides*/Insecticides*/therapeutic use

  • Source: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) [J Vet Emerg Crit Care (San Antonio)] 2023 Nov-Dec; Vol. 33 (6), pp. 705-709. Date of Electronic Publisher: Blackwell Country of Publication: United States NLM ID: 101152804 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pralidoxime-like reactivator with increased lipophilicity - Molecular modeling and in vitro study.

  • Authors : Kuca K; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic; Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic. Electronic address: .

Subjects: Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/chemistry ; Organophosphate Poisoning*; Humans

  • Source: Chemico-biological interactions [Chem Biol Interact] 2023 Nov 01; Vol. 385, pp. 110734. Date of Electronic Publication: 2023 Oct 01.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Organophosphorus Compounds Poisoning in a Neonate: A Case Report.

  • Authors : Das JC; Professor Jagadish C Das, Professor, Department of Neonatology, Chittagong Medical College (CMC), Chittagong, Bangladesh; E-mail: .

Subjects: Antidotes/Antidotes/Antidotes/*administration & dosage ; Atropine/Atropine/Atropine/*administration & dosage ; Insecticides/Insecticides/Insecticides/*poisoning

  • Source: Mymensingh medical journal : MMJ [Mymensingh Med J] 2019 Apr; Vol. 28 (2), pp. 470-473.Publisher: Mymensingh Medical College Country of Publication: Bangladesh NLM ID: 9601799 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs.

  • Authors : Shih TM; Medical Toxicology Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA. Electronic address: .; Oyler BL

Subjects: Sarin*; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Antidotes/Antidotes/Antidotes/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 15; Vol. 415, pp. 115443. Date of Electronic Publication: 2021 Feb 04.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Outcomes of elderly patients with organophosphate intoxication.

  • Authors : Yu JR; Department of Nephrology, Clinical Poison Center, Kidney Research Center, Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, and Chang Gung University, 199 Tung Hwa North Road, Taipei, Taoyuan, 105, Taiwan.; Hou YC

Subjects: Acute Kidney Injury/Acute Kidney Injury/Acute Kidney Injury/*drug therapy ; Antidotes/Antidotes/Antidotes/*therapeutic use ; Insecticides/Insecticides/Insecticides/*toxicity

  • Source: Scientific reports [Sci Rep] 2021 Jun 02; Vol. 11 (1), pp. 11615. Date of Electronic Publication: 2021 Jun 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.

  • Authors : Arshad M; a Department of Biosciences , COMSATS Institute of Information Technology , Islamabad , Pakistan.; Fatmi MQ

Subjects: Molecular Docking Simulation*; Antidotes/Antidotes/Antidotes/*pharmacology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity

  • Source: Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Jan; Vol. 28 (1), pp. 62-68. Date of Electronic Publication: 2017 Aug 04.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [ 11 C]2-Pyridinealdoxime Methiodide ([ 11 C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.

  • Authors : Neumann KD; Department of Radiology and Biomedical Imaging , University of California, San Francisco , San Francisco , California 94143 , United States.; Blecha JE

Subjects: Organophosphate Poisoning*; Antidotes/Antidotes/Antidotes/*pharmacokinetics ; Carbon Radioisotopes/Carbon Radioisotopes/Carbon Radioisotopes/*pharmacokinetics

  • Source: ACS chemical neuroscience [ACS Chem Neurosci] 2018 Dec 19; Vol. 9 (12), pp. 3007-3014. Date of Electronic Publication: 2018 Aug 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Functional basis for dose-dependent antagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4.

  • Authors : Machamer JB; Department of Neuroscience, U.S. Army Medical Research Institute of Chemical Defense, 8350 Ricketts Point Road, Gunpowder, MD, 21010, USA.; Apland JP

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*drug effects ; Muscles/Muscles/Muscles/*drug effects ; Organophosphate Poisoning/Organophosphate Poisoning/Organophosphate Poisoning/*drug therapy

  • Source: Archives of toxicology [Arch Toxicol] 2020 Nov; Vol. 94 (11), pp. 3877-3891. Date of Electronic Publication: 2020 Jul 20.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanism of central hypopnoea induced by organic phosphorus poisoning.

  • Authors : Nomura K; Department of Emergency Medicine, Sapporo Medical University Hospital, Minami1-jo nishi 16 Chome 291, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan. .; Narimatsu E

Subjects: Organophosphate Poisoning/Organophosphate Poisoning/Organophosphate Poisoning/*complications ; Sleep Apnea, Central/Sleep Apnea, Central/Sleep Apnea, Central/*chemically induced; Animals

  • Source: Scientific reports [Sci Rep] 2020 Sep 28; Vol. 10 (1), pp. 15834. Date of Electronic Publication: 2020 Sep 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  223 results for ""Pralidoxime Compounds""