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Academic Journal

Formation of an RNA Quadruplex-Duplex Hybrid in Living Cells between mRNA of the Epidermal Growth Factor Receptor (EGFR) and a G-Rich Antisense Oligoribonucleotide.

  • Authors : Gudanis D; Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland.; Kaniowski D

Subjects: G-Quadruplexes*; ErbB Receptors/ErbB Receptors/ErbB Receptors/*metabolism ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*metabolism

  • Source: Cells [Cells] 2020 Oct 29; Vol. 9 (11). Date of Electronic Publication: 2020 Oct 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

BACE1 Inhibition Using 2'-OMePS Steric Blocking Antisense Oligonucleotides.

  • Authors : Chakravarthy M; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth 6150, Australia. .; Perron Institute for Neurological and Translational Science, Perth 6150, Australia. .

Subjects: Down-Regulation*; Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*genetics ; Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/*genetics

  • Source: Genes [Genes (Basel)] 2019 Sep 12; Vol. 10 (9). Date of Electronic Publication: 2019 Sep 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425

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Academic Journal

Aberrant methylation-mediated downregulation of lncRNA SSTR5-AS1 promotes progression and metastasis of laryngeal squamous cell carcinoma.

  • Authors : Wang B; Otolaryngology Head and Neck Surgery Department, The Second Hospital of Hebei Medical University, Heping West Road 215, Shijiazhuang, 050005, Hebei, China. .; Zhao L

Subjects: DNA Methylation*; Laryngeal Neoplasms/Laryngeal Neoplasms/Laryngeal Neoplasms/*genetics ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*genetics

  • Source: Epigenetics & chromatin [Epigenetics Chromatin] 2019 Jun 13; Vol. 12 (1), pp. 35. Date of Electronic Publication: 2019 Jun 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101471619 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8935

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Academic Journal

Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse.

  • Authors : Rimessi P; Department of Experimental and Diagnostic Medicine, Section of Medical Genetics, University of Ferrara, Ferrara, Italy.; Sabatelli P

Subjects: Dystrophin/Dystrophin/Dystrophin/*metabolism ; Nanoparticles/Nanoparticles/Nanoparticles/*chemistry ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*physiology

  • Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2009 May; Vol. 17 (5), pp. 820-7. Date of Electronic Publication: 2009 Feb 24.Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNA-Targeted Therapeutics.

  • Authors : Crooke ST; Ionis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA. Electronic address: .; Witztum JL

Subjects: Molecular Targeted Therapy*; Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/*therapy ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*therapeutic use

  • Source: Cell metabolism [Cell Metab] 2018 Apr 03; Vol. 27 (4), pp. 714-739.Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print Cited Medium: Internet ISSN: 1932-7420

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Academic Journal

Gys1 antisense therapy rescues neuropathological bases of murine Lafora disease.

  • Authors : Ahonen S; Program in Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.; Nitschke S

Subjects: Glycogen Synthase/Glycogen Synthase/Glycogen Synthase/*administration & dosage ; Lafora Disease/Lafora Disease/Lafora Disease/*drug therapy ; Lafora Disease/Lafora Disease/Lafora Disease/*pathology

  • Source: Brain : a journal of neurology [Brain] 2021 Nov 29; Vol. 144 (10), pp. 2985-2993.Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN:

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Periodical

RNA drugs custommade for rare diseases face wider test.

Subjects: Genetic Diseases, Inborn/Genetic Diseases, Inborn/Genetic Diseases, Inborn/*drug therapy ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*therapeutic use ; Rare Diseases/Rare Diseases/Rare Diseases/*drug therapy

  • Source: Science (New York, N.Y.) [Science] 2021 Nov 05; Vol. 374 (6568), pp. 672. Date of Electronic Publication: 2021 Nov 04.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Assessment of External Guide Sequences' (EGS) Efficiency as Inducers of RNase P-Mediated Cleavage of mRNA Target Molecules.

  • Authors : Jani S; Center for Applied Biotechnology Studies, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA, USA.; Jackson A

Subjects: Bacteria/Bacteria/Bacteria/*genetics ; Cell-Penetrating Peptides/Cell-Penetrating Peptides/Cell-Penetrating Peptides/*pharmacology ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*metabolism

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1737, pp. 89-98.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

2'-O-modified oligoribonucleotides with terminal 3'-3'-internucleotide linkage and their derivatives.

Subjects: Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*chemical synthesis; Kinetics ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/chemistry

  • Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2001 Apr-Jul; Vol. 20 (4-7), pp. 903-7.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print Cited Medium: Print ISSN: 1525-7770

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Academic Journal

Effective treatment of murine leukemia with antisense poly-2'O-(2,4-dinitrophenyl)-oligoribonucleotides.

  • Authors : Wang A; Bioenergetics Laboratory, Natural Sciences Center, State University of New York at Buffalo, 14260-3000, USA.; Wang JH

Subjects: Leukemia, Experimental/Leukemia, Experimental/Leukemia, Experimental/*drug therapy ; Moloney murine leukemia virus/Moloney murine leukemia virus/Moloney murine leukemia virus/*genetics ; Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/Oligoribonucleotides, Antisense/*therapeutic use

  • Source: Antisense & nucleic acid drug development [Antisense Nucleic Acid Drug Dev] 1999 Feb; Vol. 9 (1), pp. 43-51.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9606142 Publication Model: Print Cited Medium: Print ISSN:

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  • 1-10 of  164 results for ""Oligoribonucleotides""