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Academic Journal

Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.

  • Authors : Xu WF; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism, China Pharmaceutical University, Nanjing, 210009, China.; Zhang Q

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Caspase 3/Caspase 3/Caspase 3/*metabolism ; Caspase Inhibitors/Caspase Inhibitors/Caspase Inhibitors/*therapeutic use

  • Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Jan; Vol. 42 (1), pp. 68-76. Date of Electronic Publication: 2020 May 26.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The Smac mimetic BV6 cooperates with STING to induce necroptosis in apoptosis-resistant pancreatic carcinoma cells.

  • Authors : Hannes S; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528, Frankfurt, Germany.; General and Visceral Surgery, Goethe-University, Frankfurt, Germany.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Necroptosis*/Necroptosis*/Necroptosis*/drug effects; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: Cell death & disease [Cell Death Dis] 2021 Aug 30; Vol. 12 (9), pp. 816. Date of Electronic Publication: 2021 Aug 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

An unexpected switch in peptide binding mode: from simulation to substrate specificity.

  • Authors : Kahler U; a Faculty of Chemistry and Pharmacy, Institute of General, Inorganic and Theoretical Chemistry , University Innsbruck , Innrain 82, Innsbruck A-6020 , Austria.; Fuchs JE

Subjects: Molecular Dynamics Simulation*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemistry ; Kallikreins/Kallikreins/Kallikreins/*chemistry

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2018 Nov; Vol. 36 (15), pp. 4072-4084. Date of Electronic Publication: 2018 Jan 31.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Entecavir combined with furin inhibitor simultaneously reduces hepatitis B virus replication and e antigen secretion.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Furin/Furin/Furin/*antagonists & inhibitors ; Guanine/Guanine/Guanine/*analogs & derivatives

  • Source: Virology journal [Virol J] 2014 Sep 16; Vol. 11, pp. 165. Date of Electronic Publication: 2014 Sep 16.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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Academic Journal

Therapeutic potential of furin inhibitors for the chronic infection of hepatitis B virus.

  • Authors : Pang YJ; Hepatology Laboratory, The Hospital for Liver Disease, Sun Yat-Sen University, Guangzhou, China.; Tan XJ

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Furin/Furin/Furin/*antagonists & inhibitors

  • Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2013 Sep; Vol. 33 (8), pp. 1230-8. Date of Electronic Publication: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis and inhibitory effect of pentapeptidyl chloromethyl ketones on proteinase K.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemical synthesis ; Endopeptidase K/Endopeptidase K/Endopeptidase K/*antagonists & inhibitors ; Ketones/Ketones/Ketones/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2010 Dec 01; Vol. 18 (23), pp. 8383-7. Date of Electronic Publication: 2010 Sep 25.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanisms of growth inhibition in human papillomavirus positive and negative cervical cancer cells by the chloromethyl ketone protease inhibitor, succinyl-alanine-alanine-proline-phenylalanine chloromethyl ketone.

  • Authors : Duncan KJ; Jake Gittlen Cancer Research Foundation, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA.; Eckert KA

Subjects: Papillomaviridae*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Growth Inhibitors/Growth Inhibitors/Growth Inhibitors/*therapeutic use

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2009 Jul; Vol. 330 (1), pp. 359-66. Date of Electronic Publication: 2009 Apr 28.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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Academic Journal

Central injection of caspase inhibitors facilitates the formation of freezing behavior in rats.

  • Authors : Markina EV; P K Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia. ; Storozheva ZI

Subjects: Behavior, Animal* ; Caspase Inhibitors*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology

  • Source: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2007 May; Vol. 143 (5), pp. 566-8.Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print Cited Medium: Print ISSN: 0007-4888 (Print)

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Academic Journal

Smac mimetic triggers necroptosis in pancreatic carcinoma cells when caspase activation is blocked.

  • Authors : Hannes S; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstr. 3a, 60528 Frankfurt, Germany; General and Visceral Surgery, Goethe-University, Frankfurt, Germany.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: Cancer letters [Cancer Lett] 2016 Sep 28; Vol. 380 (1), pp. 31-8. Date of Electronic Publication: 2016 Jun 03.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).

  • Authors : Mantoan L; Clinical Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020, Innsbruck, Austria.; Stefanova N

Subjects: Caspase Inhibitors*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Multiple System Atrophy/Multiple System Atrophy/Multiple System Atrophy/*drug therapy

  • Source: Acta neuropathologica [Acta Neuropathol] 2005 Feb; Vol. 109 (2), pp. 191-7. Date of Electronic Publication: 2004 Nov 10.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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  • 1-10 of  58 results for ""Amino Acid Chloromethyl Ketones""