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Academic Journal

The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21.

  • Authors : Lassot I; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France. Electronic address: .; Mora S

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Cell reports [Cell Rep] 2018 Nov 27; Vol. 25 (9), pp. 2484-2496.e9.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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Academic Journal

Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.

  • Authors : Feng Y; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA.; Sessions EH

Subjects: Melanoma/Melanoma/Melanoma/*drug therapy ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*antagonists & inhibitors ; Prostatic Neoplasms/Prostatic Neoplasms/Prostatic Neoplasms/*drug therapy

  • Source: Cancer letters [Cancer Lett] 2019 May 01; Vol. 449, pp. 145-162. Date of Electronic Publication: 2019 Feb 14.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation.

  • Authors : Ji L; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, USA.; Jiang B

Subjects: Signal Transduction*; Axin Protein/Axin Protein/Axin Protein/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Genes & development [Genes Dev] 2017 May 01; Vol. 31 (9), pp. 904-915. Date of Electronic Publication: 2017 May 25.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear.

  • Authors : Zhang Q; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Wang Z

Subjects: Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*chemistry ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*chemistry; Amino Acid Sequence

  • Source: Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2017 Jan; Vol. 1861 (1 Pt A), pp. 3095-3105. Date of Electronic Publication: 2016 Oct 21.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731726 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0304-4165

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Academic Journal

The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.

  • Authors : Xu P; Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.; Liu Y

Subjects: Nuclear Proteins*/Nuclear Proteins*/Nuclear Proteins*/metabolism ; Nucleosomes*/Nucleosomes*/Nucleosomes*/chemistry ; Nucleosomes*/Nucleosomes*/Nucleosomes*/metabolism

  • Source: Nature [Nature] 2024 Mar; Vol. 627 (8005), pp. 873-879. Date of Electronic Publication: 2024 Feb 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.

  • Authors : Hang LE; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Peng J

Subjects: DNA Replication* ; Gene Expression Regulation, Fungal*; Endodeoxyribonucleases/Endodeoxyribonucleases/Endodeoxyribonucleases/*genetics

  • Source: Molecular cell [Mol Cell] 2015 Oct 15; Vol. 60 (2), pp. 268-79. Date of Electronic Publication: 2015 Oct 01.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity.

  • Authors : Humphries F; Institute of Immunology, Department of Biology, National University of Ireland Maynooth, Maynooth, Ireland.; Moynagh PN

Subjects: Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism ; Receptors, Pattern Recognition/Receptors, Pattern Recognition/Receptors, Pattern Recognition/*metabolism ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*metabolism

  • Source: Immunological reviews [Immunol Rev] 2015 Jul; Vol. 266 (1), pp. 93-108.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print Cited Medium: Internet ISSN: 1600-065X (Electronic)

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Academic Journal

SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.

  • Authors : Adam MG; a Cellular Senescence Group ; German Cancer Research Center DKFZ

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Cell Movement/Cell Movement/Cell Movement/*genetics ; Neoplasm Invasiveness/Neoplasm Invasiveness/Neoplasm Invasiveness/*genetics

  • Source: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2015; Vol. 14 (23), pp. 3734-47.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers.

  • Authors : Knauer SK; Department of Molecular Biology, Centre for Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstr. 5, 45141 Essen, Germany.; Mahendrarajah N

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*enzymology ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism ; Prostatic Neoplasms/Prostatic Neoplasms/Prostatic Neoplasms/*enzymology

  • Source: Cytokine & growth factor reviews [Cytokine Growth Factor Rev] 2015 Aug; Vol. 26 (4), pp. 405-13. Date of Electronic Publication: 2015 May 12.Publisher: Elsevier Science Country of Publication: England NLM ID: 9612306 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

E3 ubiquitin ligases Pellinos as regulators of pattern recognition receptor signaling and immune responses.

  • Authors : Medvedev AE; Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA.; Murphy M

Subjects: Immunotherapy*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Immunological reviews [Immunol Rev] 2015 Jul; Vol. 266 (1), pp. 109-22.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print Cited Medium: Internet ISSN: 1600-065X (Electronic)

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  • 1-10 of  944 results for ""UBIQUITIN ligases""