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Academic Journal

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

  • Authors : Sasmita AO; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. .; International Max Planck Research School for Neurosciences, Göttingen, Germany. .

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

  • Source: Nature neuroscience [Nat Neurosci] 2024 Sep; Vol. 27 (9), pp. 1668-1674. Date of Electronic Publication: 2024 Aug 05.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Neuronal activity and amyloid plaque pathology: an update.

  • Authors : Ovsepian SV; International Centre for Neurotherapeutics, Dublin City University, Dublin, Republic of Ireland.; O'Leary VB

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*physiopathology ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Neurons/Neurons/Neurons/*cytology

  • Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2016; Vol. 49 (1), pp. 13-9.Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9814863 Publication Model: Print Cited Medium: Internet ISSN: 1875-8908

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Academic Journal

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.

  • Authors : Xiao Q; Department of Neurology and the Hope Center for Neurological Disorders.; Yan P

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*metabolism ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*metabolism

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2015 Sep 02; Vol. 35 (35), pp. 12137-51.Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice.

  • Authors : DaRocha-Souto B; Neurology Department, Massachusetts General Hospital, Harvard University, Boston, Massachusetts 02114, USA.; Scotton TC

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*metabolism ; Astrocytes/Astrocytes/Astrocytes/*metabolism

  • Source: Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2011 May; Vol. 70 (5), pp. 360-76.Publisher: Oxford University Press Country of Publication: England NLM ID: 2985192R Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Does beta-amyloid plaque formation cause structural injury to neuronal processes?

  • Authors : Woodhouse A; NeuroRepair Group, School of Medicine, University of Tasmania, Australia.; West AK

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*toxicity ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*metabolism

  • Source: Neurotoxicity research [Neurotox Res] 2005; Vol. 7 (1-2), pp. 5-15.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print Cited Medium: Print ISSN: 1029-8428 (Print)

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Academic Journal

Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathology.

  • Authors : Mohajeri MH; Division of Psychiatry Research, University of Zurich, Zurich, Switzerland. ; Saini KD

Subjects: Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/*metabolism ; Brain/Brain/Brain/*metabolism ; Brain/Brain/Brain/*pathology

  • Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2004 Mar; Vol. 111 (3), pp. 413-25. Date of Electronic Publication: 2003 Dec 03.Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

  • Authors : Dewachter I; Experimental Genetics Group, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium, Laboratory of Neuroscience, University of Mons-Hainaut, 7000 Mons, Belgium.; Reversé D

Subjects: Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*metabolism ; Cognition Disorders/Cognition Disorders/Cognition Disorders/*physiopathology ; Hippocampus/Hippocampus/Hippocampus/*metabolism

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2002 May 01; Vol. 22 (9), pp. 3445-53.Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology.

  • Authors : Rossner S; Paul Flechsig Institute for Brain Research, Department of Neurochemistry, University of Leipzig, Jahnallee 59, D-04109 Leipzig, Germany. ; Apelt J

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*enzymology ; Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/Aspartic Acid Endopeptidases/*metabolism ; Brain/Brain/Brain/*enzymology

  • Source: Journal of neuroscience research [J Neurosci Res] 2001 Jun 01; Vol. 64 (5), pp. 437-46.Publisher: Wiley Interscience Country of Publication: United States NLM ID: 7600111 Publication Model: Print Cited Medium: Print ISSN: 0360-4012

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Academic Journal

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

  • Authors : Chui DH; Department of Demyelinating Disease and Aging, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan.; Tanahashi H

Subjects: Plaque, Amyloid*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*genetics ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology

  • Source: Nature medicine [Nat Med] 1999 May; Vol. 5 (5), pp. 560-4.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Print ISSN:

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  • 1-10 of  1,369 results for ""AMYLOID plaque""