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Academic Journal

Synergistic epistasis among cancer drivers can rescue early tumors from the accumulation of deleterious passengers.

  • Authors : Alejandre C; Centro de Astrobiología (CAB) CSIC-INTA, Torrejón de Ardoz, Madrid, Spain.; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.

Subjects: Epistasis, Genetic*/Epistasis, Genetic*/Epistasis, Genetic*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Computer Simulation*

  • Source: PLoS computational biology [PLoS Comput Biol] 2024 Apr 30; Vol. 20 (4), pp. e1012081. Date of Electronic Publication: 2024 Apr 30 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Common Attractors in Multiple Boolean Networks.

Subjects: Models, Genetic* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics; Humans

  • Source: IEEE/ACM transactions on computational biology and bioinformatics [IEEE/ACM Trans Comput Biol Bioinform] 2023 Sep-Oct; Vol. 20 (5), pp. 2862-2873. Date of Electronic Publication: Publisher: IEEE Computer Society Country of Publication: United States NLM ID: 101196755 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

  • Authors : Diaz-Colunga J; Department of Biochemistry, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.; Instituto de Investigaciones Biomédicas 'Alberto Sols' (UAM-CSIC), Madrid, Spain.

Subjects: Models, Genetic* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/pathology

  • Source: PLoS computational biology [PLoS Comput Biol] 2021 Dec 21; Vol. 17 (12), pp. e1009055. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Higher order genetic interactions switch cancer genes from two-hit to one-hit drivers.

  • Authors : Park S; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain. .; Supek F

Subjects: Genes, Tumor Suppressor* ; Models, Genetic* ; Oncogenes*

  • Source: Nature communications [Nat Commun] 2021 Dec 03; Vol. 12 (1), pp. 7051. Date of Electronic Publication: 2021 Dec 03.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exact site frequency spectra of neutrally evolving tumors: A transition between power laws reveals a signature of cell viability.

  • Authors : Gunnarsson EB; Department of Industrial and Systems Engineering, University of Minnesota, Twin Cities, MN 55455, USA. Electronic address: .; Leder K

Subjects: Models, Genetic* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics; Cell Survival/Cell Survival/Cell Survival/genetics

  • Source: Theoretical population biology [Theor Popul Biol] 2021 Dec; Vol. 142, pp. 67-90. Date of Electronic Publication: 2021 Sep 21.Publisher: Academic Press Country of Publication: United States NLM ID: 0256422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MHRWR: Prediction of lncRNA-Disease Associations Based on Multiple Heterogeneous Networks.

Subjects: Models, Genetic* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism

  • Source: IEEE/ACM transactions on computational biology and bioinformatics [IEEE/ACM Trans Comput Biol Bioinform] 2021 Nov-Dec; Vol. 18 (6), pp. 2577-2585. Date of Electronic Publication: Publisher: IEEE Computer Society Country of Publication: United States NLM ID: 101196755 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

CanDriS: posterior profiling of cancer-driving sites based on two-component evolutionary model.

  • Authors : Zhao W; College of Pharmaceutical Sciences & College of Computer Science and Technology, Zhejiang University, China.; Yang J

Subjects: Algorithms* ; Databases, Genetic* ; Models, Genetic*

  • Source: Briefings in bioinformatics [Brief Bioinform] 2021 Sep 02; Vol. 22 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A graph auto-encoder model for miRNA-disease associations prediction.

  • Authors : Li Z; Engineering Research Center of Mine Digitalization of Ministry of Education and School of Computer Science and Technology, China University of Mining and Technology.; Li J

Subjects: Databases, Genetic* ; Gene Expression Regulation, Neoplastic* ; MicroRNAs*/MicroRNAs*/MicroRNAs*/biosynthesis

  • Source: Briefings in bioinformatics [Brief Bioinform] 2021 Jul 20; Vol. 22 (4).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.

  • Authors : Han Z; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Paediatrics, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, China.; Zhang W

Subjects: Models, Genetic*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*genetics ; Macroautophagy/Macroautophagy/Macroautophagy/*genetics

  • Source: Nature communications [Nat Commun] 2021 May 31; Vol. 12 (1), pp. 3258. Date of Electronic Publication: 2021 May 31.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chromosomal copy number heterogeneity predicts survival rates across cancers.

  • Authors : van Dijk E; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; van den Bosch T

Subjects: DNA Copy Number Variations* ; Genetic Heterogeneity* ; Models, Genetic*

  • Source: Nature communications [Nat Commun] 2021 May 27; Vol. 12 (1), pp. 3188. Date of Electronic Publication: 2021 May 27.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,227 results for ""Models, Genetic""