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Academic Journal

Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer.

  • Authors : Woock AE; Department of Pathology, Virginia Commonwealth University, 1101 E. Marshall St, Sanger 4-006A, Richmond, VA, 23298-06629, USA.; Grible JM

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Jun 29; Vol. 11 (1), pp. 13506. Date of Electronic Publication: 2021 Jun 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

STAT5BN642H is a driver mutation for T cell neoplasia.

  • Authors : Pham HTT; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.

Subjects: CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*metabolism ; Hematologic Neoplasms/Hematologic Neoplasms/Hematologic Neoplasms/*metabolism ; Leukemia, T-Cell/Leukemia, T-Cell/Leukemia, T-Cell/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Jan 02; Vol. 128 (1), pp. 387-401. Date of Electronic Publication: 2017 Dec 04.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5.

  • Authors : Fu B; Department of Hepatic Surgery, Liver Transplant Center, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, P. R. China.; Liver Transplantation Center of Sun Yat-sen University, Guangzhou 510630, P. R. China.

Subjects: Gene Expression Regulation, Neoplastic*; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*pathology ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*pathology

  • Source: Scientific reports [Sci Rep] 2016 Sep 02; Vol. 6, pp. 31963. Date of Electronic Publication: 2016 Sep 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Report

High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia.

  • Authors : Andersson EI; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Tanahashi T

Subjects: CD4-Positive T-Lymphocytes* ; Mutation*; Leukemia, Large Granular Lymphocytic/Leukemia, Large Granular Lymphocytic/Leukemia, Large Granular Lymphocytic/*genetics

  • Source: Blood [Blood] 2016 Nov 17; Vol. 128 (20), pp. 2465-2468. Date of Electronic Publication: 2016 Oct 03.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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CSF3R T618I, ASXL1 G942 fs and STAT5B N642H trimutation co-contribute to a rare chronic neutrophilic leukaemia manifested by rapidly progressive leucocytosis, severe infections, persistent fever and deep venous thrombosis.

  • Authors : Luo Q; Department of Haematology, The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China.; Shen J

Subjects: Fever/Fever/Fever/*genetics ; Infections/Infections/Infections/*genetics ; Leukemia, Neutrophilic, Chronic/Leukemia, Neutrophilic, Chronic/Leukemia, Neutrophilic, Chronic/*genetics

  • Source: British journal of haematology [Br J Haematol] 2018 Mar; Vol. 180 (6), pp. 892-894. Date of Electronic Publication: 2016 Dec 16.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The new iodoacetamidobenzofuran derivative TR120 decreases STAT5 expression and induces antitumor effects in imatinib-sensitive and imatinib-resistant BCR-ABL-expressing leukemia cells.

  • Authors : Grimaudo S; Department of Biomedical Internal and Specialized Medicine, University of Palermo, Palermo, Italy.; Meli M

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/Leukemia, Myelogenous, Chronic, BCR-ABL Positive/Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*pathology ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*biosynthesis

  • Source: Anti-cancer drugs [Anticancer Drugs] 2013 Apr; Vol. 24 (4), pp. 384-93.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100823 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Repression of STAT3, STAT5A, and STAT5B expressions in chronic myelogenous leukemia cell line K-562 with unmodified or chemically modified siRNAs and induction of apoptosis.

  • Authors : Kaymaz BT; Faculty of Medicine Department of Medical Biology, Ege University, Bornova, Izmir, Turkey. ; Selvi N

Subjects: Molecular Targeted Therapy* ; RNA Interference*; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: Annals of hematology [Ann Hematol] 2013 Jan; Vol. 92 (2), pp. 151-62. Date of Electronic Publication: 2012 Oct 04.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel role for signal transducer and activator of transcription 5b (STAT5b) in beta1-integrin-mediated human breast cancer cell migration.

  • Authors : Bernaciak TM; Department of Microbiology, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA. ; Zareno J

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Integrin beta1/Integrin beta1/Integrin beta1/*physiology ; Neoplasm Invasiveness/Neoplasm Invasiveness/Neoplasm Invasiveness/*physiopathology

  • Source: Breast cancer research : BCR [Breast Cancer Res] 2009; Vol. 11 (4), pp. R52. Date of Electronic Publication: 2009 Jul 24.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.

  • Authors : Peck AR; Kimmel Cancer Center, Thomas Jefferson University, 233 S 10th St, Philadelphia, PA 19107, USA.; Witkiewicz AK

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Carcinoma, Ductal, Breast/Carcinoma, Ductal, Breast/Carcinoma, Ductal, Breast/*metabolism ; Carcinoma, Intraductal, Noninfiltrating/Carcinoma, Intraductal, Noninfiltrating/Carcinoma, Intraductal, Noninfiltrating/*metabolism

  • Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2011 Jun 20; Vol. 29 (18), pp. 2448-58. Date of Electronic Publication: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma.

  • Authors : Jinawath N; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America.; Vasoontara C

Subjects: Proteomics* ; Up-Regulation*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

  • Source: PloS one [PLoS One] 2010 Jun 18; Vol. 5 (6), pp. e11198. Date of Electronic Publication: 2010 Jun 18.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

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  • 1-10 of  82 results for ""STAT5 Transcription Factor""