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  • 1-8 of  8 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""

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Academic Journal

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

  • Authors : Vettel C; From the Institute of Experimental and Clinical Pharmacology and Toxicology, University Medical Center Mannheim, Heidelberg University, Germany (C.V., T.W.); Institute of Pharmacology, University Medical Center Göttingen (UMG) Heart Center, Georg August University Medical School Göttingen, Germany (C.V., M.D., M.R., S.M.)

Subjects: Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*metabolism ; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*biosynthesis

  • Source: Circulation research [Circ Res] 2017 Jan 06; Vol. 120 (1), pp. 120-132. Date of Electronic Publication: 2016 Oct 31.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium.

  • Authors : Moltzau LR; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Sognsvannsveien 20, P.O. Box 1057 Blindern, N-0316, Oslo, Norway.; Meier S

Subjects: Cyclic GMP/Cyclic GMP/Cyclic GMP/*biosynthesis ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*physiology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*physiology

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2014 May; Vol. 387 (5), pp. 407-17. Date of Electronic Publication: 2014 Jan 15.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

Subjects: Adrenergic beta-2 Receptor Agonists/Adrenergic beta-2 Receptor Agonists/Adrenergic beta-2 Receptor Agonists/*pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 5/Cyclic Nucleotide Phosphodiesterases, Type 5/Cyclic Nucleotide Phosphodiesterases, Type 5/*metabolism ; Heart Rate/Heart Rate/Heart Rate/*drug effects

  • Source: Cardiovascular research [Cardiovasc Res] 2015 Jun 01; Vol. 106 (3), pp. 408-20. Date of Electronic Publication: 2015 Apr 07.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy.

  • Authors : Perera RK; From the Emmy Noether Group of the DFG, European Heart Research Institute Göttingen, Göttingen, Germany (R.K.P., J.U.S., D.H., V.O.N.); Heart Research Center Göttingen, Georg August University Medical Center, Göttingen, Germany (R.K.P., J.U.S., J.H.S., D.H., S.E.L., A.E.-A., V.O.N.)

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Adrenergic beta-Agonists/Adrenergic beta-Agonists/Adrenergic beta-Agonists/*pharmacology ; Atrial Natriuretic Factor/Atrial Natriuretic Factor/Atrial Natriuretic Factor/*pharmacology

  • Source: Circulation research [Circ Res] 2015 Apr 10; Vol. 116 (8), pp. 1304-11. Date of Electronic Publication: 2015 Feb 16.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain.

  • Authors : Mohamed TMA; Cardiovascular Medicine Research Group, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PT, United Kingdom; Biochemistry Department, Faculty of Pharmacy, Zagazig University, 44519 Zagazig, Egypt.

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*metabolism ; Membrane Microdomains/Membrane Microdomains/Membrane Microdomains/*enzymology

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 Dec 02; Vol. 286 (48), pp. 41520-41529. Date of Electronic Publication: 2011 Sep 29.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.

  • Authors : Kemeny-Beke A; Department of Ophthalmology, University of Debrecen, PO Box 30, H-4012 Debrecen, Hungary.; Jakab A

Subjects: Adenosine Deaminase Inhibitors*; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Hyperthyroidism/Hyperthyroidism/Hyperthyroidism/*metabolism

  • Source: Pharmacological research [Pharmacol Res] 2007 Aug; Vol. 56 (2), pp. 124-31. Date of Electronic Publication: 2007 May 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1043-6618

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Academic Journal

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.

  • Authors : Mongillo M; Dulbecco Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy.; Tocchetti CG

Subjects: Cyclic GMP/Cyclic GMP/Cyclic GMP/*physiology ; Myocardial Contraction/Myocardial Contraction/Myocardial Contraction/*drug effects ; Nitric Oxide/Nitric Oxide/Nitric Oxide/*physiology

  • Source: Circulation research [Circ Res] 2006 Feb 03; Vol. 98 (2), pp. 226-34. Date of Electronic Publication: 2005 Dec 15.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.

  • Authors : Gesztelyi R; Department of Pharmacology and Pharmacotherapy, University of Debrecen, Debrecen, Hungary. ; Zsuga J

Subjects: Adenine/Adenine/Adenine/*analogs & derivatives ; Adenosine/Adenosine/Adenosine/*analogs & derivatives ; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*pharmacology

  • Source: General physiology and biophysics [Gen Physiol Biophys] 2003 Dec; Vol. 22 (4), pp. 501-13.Publisher: Ústav molekulárnej fyziológie a genetiky SAV Country of Publication: Slovakia NLM ID: 8400604 Publication Model: Print Cited Medium:

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  • 1-8 of  8 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""