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Academic Journal

Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho.

  • Authors : Talwar S; Center for Engineering MechanoBiology, University of Pennsylvania, Philadelphia, PA 19104, USA; Departments of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Subjects: Adaptation, Physiological*; Mechanotransduction, Cellular/Mechanotransduction, Cellular/Mechanotransduction, Cellular/*genetics ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*metabolism

  • Source: Cell reports [Cell Rep] 2021 Apr 20; Vol. 35 (3), pp. 109019.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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Academic Journal

p115 RhoGEF activates the Rac1 GTPase signaling cascade in MCP1 chemokine-induced vascular smooth muscle cell migration and proliferation.

  • Authors : Singh NK; From the Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163. Electronic address: .; Janjanam J

Subjects: Models, Biological* ; Protein Processing, Post-Translational* ; Signal Transduction*

  • Source: The Journal of biological chemistry [J Biol Chem] 2017 Aug 25; Vol. 292 (34), pp. 14080-14091. Date of Electronic Publication: 2017 Jun 27.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity.

  • Authors : Chen L; Department of Surgery and Center for Cardiovascular Biology, University of Washington, Seattle, WA, United States of America.; DeWispelaere A

Subjects: Cell Movement*; Actins/Actins/Actins/*metabolism ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*cytology

  • Source: PloS one [PLoS One] 2016 May 13; Vol. 11 (5), pp. e0155726. Date of Electronic Publication: 2016 May 13 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation.

  • Authors : Yu D; Department of Surgery, Veterans Affairs Medical Center, Baltimore, MD (D.Y., T.S.M.) Department of Surgery, University of Maryland School of Medicine, Baltimore, MD (D.Y., G.M., D.K.S., R.S., T.S.M.) Center for Vascular and Inflammatory Disease, University of Maryland School of Medicine, Baltimore, MD (D.Y., D.K.S., R.S., T.S.M.).; Makkar G

Subjects: Cell Movement* ; Neointima*; Carotid Artery Injuries/Carotid Artery Injuries/Carotid Artery Injuries/*prevention & control

  • Source: Journal of the American Heart Association [J Am Heart Assoc] 2015 Oct 08; Vol. 4 (10), pp. e002255. Date of Electronic Publication: 2015 Oct 08.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-9980

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Academic Journal

Exendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway.

  • Authors : Zhao L; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China.

Subjects: Angiotensin II/Angiotensin II/Angiotensin II/*pharmacology ; Cellular Senescence/Cellular Senescence/Cellular Senescence/*drug effects ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2014 Dec 15; Vol. 307 (12), pp. C1130-41. Date of Electronic Publication: 2014 Oct 08.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Smooth muscle specific Rac1 deficiency induces hypertension by preventing p116RIP3-dependent RhoA inhibition.

  • Authors : André G; Inserm UMR_S1087, CNRS UMR_C6291, l'institut du thorax, Nantes, F-44000, France (G.A., J.E.S., G.T., M.R.D., G.L., V.S.) Université de Nantes, Nantes, F-44000, France (G.A., J.E.S., G.T., M.R.D., G.L., V.S.).; Sandoval JE

Subjects: Hypertension/Hypertension/Hypertension/*etiology ; Microfilament Proteins/Microfilament Proteins/Microfilament Proteins/*physiology ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*physiopathology

  • Source: Journal of the American Heart Association [J Am Heart Assoc] 2014 Jun 17; Vol. 3 (3), pp. e000852. Date of Electronic Publication: 2014 Jun 17.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-9980

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Academic Journal

LPS Promotes Vascular Smooth Muscle Cells Proliferation Through the TLR4/Rac1/Akt Signalling Pathway.

  • Authors : Yin Q; Institute of Cardiovascular Disease Research, Xuzhou Medical University, Xuzhou, China.; Jiang D

Subjects: Cell Proliferation* ; Signal Transduction*; Lipopolysaccharides/Lipopolysaccharides/Lipopolysaccharides/*immunology

  • Source: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2017; Vol. 44 (6), pp. 2189-2200. Publisher: Cell Physiol Biochem Press GmbH & Co KG Country of Publication: Germany NLM ID: 9113221 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Regulatory effect of Rac1 on vascular reactivity after hemorrhagic shock in rats.

  • Authors : Li T; State Key Laboratory of Trauma, Burns and Combined Injury, Second Department of Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, P R China.; Yang G

Subjects: Mesenteric Artery, Superior/Mesenteric Artery, Superior/Mesenteric Artery, Superior/*physiopathology ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*drug effects ; Shock, Hemorrhagic/Shock, Hemorrhagic/Shock, Hemorrhagic/*physiopathology

  • Source: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2011 Jun; Vol. 57 (6), pp. 656-65.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation.

  • Authors : Pescatore LA; Vascular Biology Laboratory, Heart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil 05403-000.; Bonatto D

Subjects: Cell Movement/Cell Movement/Cell Movement/*physiology ; Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/*physiology ; Muscle Proteins/Muscle Proteins/Muscle Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2012 Aug 24; Vol. 287 (35), pp. 29290-300. Date of Electronic Publication: 2012 Jul 06.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation.

  • Authors : Huh JY; Division of Life & Pharmaceutical Sciences and Center for Cell Signaling & Drug Discovery Research, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.; Son DJ

Subjects: Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*physiology ; Deoxyguanosine/Deoxyguanosine/Deoxyguanosine/*analogs & derivatives ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*drug effects

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2012 Jul 01; Vol. 53 (1), pp. 109-21. Date of Electronic Publication: 2012 Apr 19.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  80 results for ""rac1 GTP-Binding Protein""