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  • 1-10 of  27 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""

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Academic Journal

Role of PDE3A in regulation of cell cycle progression in mouse vascular smooth muscle cells and oocytes: implications in cardiovascular diseases and infertility.

  • Authors : Begum N; Cardiovascular Pulmonary Branch, NHLBI, National Institutes of Health, Bethesda, MD 20892, United States. ; Shen W

Subjects: Cell Cycle*/Cell Cycle*/Cell Cycle*/drug effects; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*drug therapy ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism

  • Source: Current opinion in pharmacology [Curr Opin Pharmacol] 2011 Dec; Vol. 11 (6), pp. 725-9. Date of Electronic Publication: 2011 Nov 01.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.

  • Authors : Begum N; Cardiovascular-Pulmonary Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA. ; Hockman S

Subjects: Gene Deletion*; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*deficiency

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 Jul 22; Vol. 286 (29), pp. 26238-49. Date of Electronic Publication: 2011 Jun 01.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Inhibition of phosphodiesterase type 3 dilates the rat ductus arteriosus without inducing intimal thickening.

  • Authors : Ichikawa Y; Cardiovascular Research Institute, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan.; Yokoyama U

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*biosynthesis ; Ductus Arteriosus/Ductus Arteriosus/Ductus Arteriosus/*enzymology ; Ductus Arteriosus/Ductus Arteriosus/Ductus Arteriosus/*physiopathology

  • Source: Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2012; Vol. 76 (10), pp. 2456-64. Date of Electronic Publication: 2012 Jul 06.Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

β-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cells.

  • Authors : Zhai K; Inserm UMR-S 769, LabEx LERMIT, Châtenay-Malabry, France.; Hubert F

Subjects: Adrenergic beta-Agonists/Adrenergic beta-Agonists/Adrenergic beta-Agonists/*pharmacology ; Adrenergic beta-Antagonists/Adrenergic beta-Antagonists/Adrenergic beta-Antagonists/*pharmacology ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: PloS one [PLoS One] 2012; Vol. 7 (10), pp. e47826. Date of Electronic Publication: 2012 Oct 18.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The function of vascular smooth muscle phosphodiesterase III is preserved in healthy human aging.

  • Authors : Elvebak RL; Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.; Eisenach JH

Subjects: Health*; Aging/Aging/Aging/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism

  • Source: Clinical and translational science [Clin Transl Sci] 2010 Oct; Vol. 3 (5), pp. 239-42.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Thrombospondin-1 inhibition of vascular smooth muscle cell responses occurs via modulation of both cAMP and cGMP.

  • Authors : Yao M; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.; Roberts DD

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Vasodilation*/Vasodilation*/Vasodilation*/drug effects; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: Pharmacological research [Pharmacol Res] 2011 Jan; Vol. 63 (1), pp. 13-22. Date of Electronic Publication: 2010 Oct 29.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.

  • Authors : Nino G; Joseph Stokes Jr. Research Institute, Division of Pulmonary Medicine, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.; Hu A

Subjects: Desensitization, Immunologic*; Asthma/Asthma/Asthma/*metabolism ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*immunology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2009 Oct; Vol. 297 (4), pp. L746-57. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Multifaceted effects of selective inhibitor of phosphodiesterase III, cilostazol, for cerebral vasospasm after subarachnoid hemorrhage in a dog model.

Subjects: Phosphodiesterase 3 Inhibitors*; Endothelium, Vascular/Endothelium, Vascular/Endothelium, Vascular/*drug effects ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*drug effects

  • Source: Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2009; Vol. 28 (2), pp. 135-42. Date of Electronic Publication: 2009 Jun 05.Publisher: Karger Country of Publication: Switzerland NLM ID: 9100851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9786

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Academic Journal

Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition.

  • Authors : Dony E; University of Giessen Lung Centre (UGLC), Klinikstrasse 36, 35392 Giessen, Germany.; Lai YJ

Subjects: Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*drug therapy ; Hypertrophy, Right Ventricular/Hypertrophy, Right Ventricular/Hypertrophy, Right Ventricular/*drug therapy ; Lung/Lung/Lung/*drug effects

  • Source: The European respiratory journal [Eur Respir J] 2008 Mar; Vol. 31 (3), pp. 599-610. Date of Electronic Publication: 2007 Nov 21.Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Effects of a phosphodiesterase 3 inhibitor, olprinone, on rhythmical change in tension of human gastroepiploic artery.

  • Authors : Adachi H; Regulatory Science Operations Department, Eisai Co., Ltd., Koishikawa 4-6-10, Bunkyo-ku, Tokyo 112-8088, Japan. ; Kakiki M

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*antagonists & inhibitors ; Imidazoles/Imidazoles/Imidazoles/*pharmacology ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*drug effects

  • Source: European journal of pharmacology [Eur J Pharmacol] 2005 Dec 28; Vol. 528 (1-3), pp. 137-43. Date of Electronic Publication: 2005 Dec 02.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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  • 1-10 of  27 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""