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Academic Journal

Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures.

  • Authors : Pekthong D; Laboratoire de Toxicologie Cellulaire, EA 4267, IFR 133, UFR Pharmacie, Place Saint-Jacques, 25030 Besançon, France.; Blanchard N

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Andrographis/Andrographis/Andrographis/*chemistry ; Diterpenes/Diterpenes/Diterpenes/*pharmacology

  • Source: Chemico-biological interactions [Chem Biol Interact] 2009 May 15; Vol. 179 (2-3), pp. 247-55. Date of Electronic Publication: 2008 Nov 08.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.

  • Authors : Haines DC; Department of Chemistry, The University of Texas at Dallas, Dallas, Texas 75083-0688, USA.; Chen B

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*antagonists & inhibitors ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry

  • Source: Biochemistry [Biochemistry] 2008 Mar 25; Vol. 47 (12), pp. 3662-70. Date of Electronic Publication: 2008 Feb 26.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Structure-activity relationship of uniconazole, a potent inhibitor of ABA 8'-hydroxylase, with a focus on hydrophilic functional groups and conformation.

  • Authors : Todoroki Y; Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan. ; Kobayashi K

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Mixed Function Oxygenases/Mixed Function Oxygenases/Mixed Function Oxygenases/*antagonists & inhibitors ; Triazoles/Triazoles/Triazoles/*chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2008 Mar 15; Vol. 16 (6), pp. 3141-52. Date of Electronic Publication: 2008 Mar 04.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Potent cytochrome P450 2C19 genotype-related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir.

  • Authors : Mikus G; Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany. ; Schöwel V

Subjects: Cytochrome P-450 Enzyme Inhibitors* ; Enzyme Inhibitors*; Anti-HIV Agents/Anti-HIV Agents/Anti-HIV Agents/*adverse effects

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2006 Aug; Vol. 80 (2), pp. 126-35. Date of Electronic Publication: 2006 Jul 03.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0009-9236

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Academic Journal

A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis.

  • Authors : Saito S; Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.; Okamoto M

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Abscisic Acid/Abscisic Acid/Abscisic Acid/*metabolism ; Arabidopsis/Arabidopsis/Arabidopsis/*metabolism

  • Source: Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2006 Jul; Vol. 70 (7), pp. 1731-9. Date of Electronic Publication: 2006 Jul 01.Publisher: Oxford University Press Country of Publication: England NLM ID: 9205717 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2).

  • Authors : Zhao B; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA. ; Waterman MR

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Mixed Function Oxygenases/Mixed Function Oxygenases/Mixed Function Oxygenases/*chemistry ; Mixed Function Oxygenases/Mixed Function Oxygenases/Mixed Function Oxygenases/*metabolism

  • Source: Biochemistry [Biochemistry] 2006 Jun 20; Vol. 45 (24), pp. 7493-500.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

A new non-azole inhibitor of ABA 8'-hydroxylase: effect of the hydroxyl group substituted for geminal methyl groups in the six-membered ring.

  • Authors : Araki Y; Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan.; Miyawaki A

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemical synthesis ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Jun 15; Vol. 16 (12), pp. 3302-5. Date of Electronic Publication: 2006 Mar 24.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.

  • Authors : Nithipatikom K; Dept. of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226, USA.; Endsley MP

Subjects: Cytochrome P-450 Enzyme Inhibitors* ; Ischemic Preconditioning, Myocardial*; Mixed Function Oxygenases/Mixed Function Oxygenases/Mixed Function Oxygenases/*antagonists & inhibitors

  • Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2006 Feb; Vol. 290 (2), pp. H500-5. Date of Electronic Publication: 2005 Oct 07.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

A lead compound for the development of ABA 8'-hydroxylase inhibitors.

  • Authors : Ueno K; The United Graduate School of Agricultural Science, Gifu University, Gifu 501-1193, Japan.; Yoneyama H

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Abscisic Acid/Abscisic Acid/Abscisic Acid/*analogs & derivatives ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemistry

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Dec 01; Vol. 15 (23), pp. 5226-9. Date of Electronic Publication: 2005 Sep 16.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.

  • Authors : Li XQ; DMPK and Bioanalytical Chemistry, AstraZeneca R&D Mölndal, Sweden. ; Weidolf L

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/Aryl Hydrocarbon Hydroxylases/*antagonists & inhibitors ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2005 Nov; Vol. 315 (2), pp. 777-87. Date of Electronic Publication: 2005 Aug 10.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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  • 1-10 of  466 results for ""Cytochrome P-450 Enzyme Inhibitors""