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Academic Journal

New molecular mechanisms to explain the neuroprotective effects of insulin-like growth factor II in a cellular model of Parkinson's disease.

  • Authors : Romero-Zerbo SY; Departamento de Fisiología Humana, Facultad de Medicina, Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga (UMA), Malaga 29010, Spain.; Valverde N

Subjects: Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy

  • Source: Journal of advanced research [J Adv Res] 2025 Jan; Vol. 67, pp. 349-359. Date of Electronic Publication: 2024 Feb 08.Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic

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Academic Journal

[Parkin deletion affects PINK1/Parkin-mediated mitochondrial autophagy to exacerbate neuroinflammation and accelerate progression of Parkinson's disease in mice].

  • Authors : Jiang C; Anhui Provincial Center for Neural Regeneration Technology and New Medical Materials Engineering Research, Bengbu Medical University, Bengbu 233000, China.; Li Y

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Mice, Inbred C57BL*

  • Source: Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2024 Dec 20; Vol. 44 (12), pp. 2359-2366.Publisher: Nanfang yi ke da xue xue bao bian ji bu Country of Publication: China NLM ID: 101266132 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Mitochondria-targeted oligomeric α-synuclein induces TOM40 degradation and mitochondrial dysfunction in Parkinson's disease and parkinsonism-dementia of Guam.

  • Authors : Vasquez V; Division of DNA Repair Research, Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX, USA.; Neuroscience Center, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, (INDICASAT AIP), Panama City, Panama.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

  • Source: Cell death & disease [Cell Death Dis] 2024 Dec 18; Vol. 15 (12), pp. 914. Date of Electronic Publication: 2024 Dec 18.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antibody conjugated targeted nanotherapy epigenetically inhibits calpain-mediated mitochondrial dysfunction to attenuate Parkinson's disease.

  • Authors : Biswal L; Epigenetics Research Laboratory, Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali, Punjab 140306, India.; Sahu VK

Subjects: Mitochondria*/Mitochondria*/Mitochondria*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Calpain*/Calpain*/Calpain*/metabolism

  • Source: Carbohydrate polymers [Carbohydr Polym] 2024 Dec 15; Vol. 346, pp. 122575. Date of Electronic Publication: 2024 Aug 03.Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

From mitochondrial dysfunction to neuroinflammation in Parkinson's disease: Pathogenesis and mitochondrial therapeutic approaches.

  • Authors : Ebadpour N; Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Immunology Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/therapy ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt A), pp. 113015. Date of Electronic Publication: 2024 Sep 01.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mitochondrial dysfunction in Parkinson's disease.

  • Authors : Hattori N; Department of Neurology, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo, Tokyo, 113-8421, Japan. .; Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, 2-1-Hirosawa, Wako-Shi, Saitama, 351-0198, Japan. .

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/genetics ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology

  • Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2024 Dec; Vol. 131 (12), pp. 1415-1428. Date of Electronic Publication: 2024 Nov 25.Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mitochondrial E3 ligase TRIM71 affects mitochondrial complex assembly and sensitizes dopaminergic neuronal cells to apoptosis in Parkinson's Disease (PD).

  • Authors : Goyani S; Department of Biochemistry, Faculty of Science, The M.S. University of Baroda, Vadodara, Gujarat 390 002, India.; Shukla S

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Dopaminergic Neurons*/Dopaminergic Neurons*/Dopaminergic Neurons*/metabolism

  • Source: The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Dec; Vol. 177, pp. 106689. Date of Electronic Publication: 2024 Nov 08.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9508482 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

LRRK2 G2019S Mutated iPSC-Derived Endothelial Cells Exhibit Increased α-Synuclein, Mitochondrial Impairment, and Altered Inflammatory Responses.

  • Authors : Sonninen TM; A.I. Virtanen Institute, University of Eastern Finland, 70211 Kuopio, Finland.; Peltonen S

Subjects: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 29; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Binding of α-synuclein to ACO2 promotes progressive mitochondrial dysfunction in Parkinson's disease models.

  • Authors : Jiao J; Department of Neurobiology, School of Basic Medical Sciences, Capital Medical University, Beijing Key Laboratory of Neural Regeneration and Repair, Beijing Key Laboratory on Parkinson's Disease, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Institute of Brain Disorders, Collaborative Innovation Center for Brain Disorders, Beijing, China.; Gao G

Subjects: Aconitate Hydratase*/Aconitate Hydratase*/Aconitate Hydratase*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics

  • Source: Redox biology [Redox Biol] 2024 Nov; Vol. 77, pp. 103399. Date of Electronic Publication: 2024 Oct 17.Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting mitochondria with small molecules: A promising strategy for combating Parkinson's disease.

  • Authors : Pal C; Department of Chemistry, Gobardanga Hindu College, North 24 Parganas, West Bengal 743273, India. Electronic address: .

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects

  • Source: Mitochondrion [Mitochondrion] 2024 Nov; Vol. 79, pp. 101971. Date of Electronic Publication: 2024 Sep 30.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100968751 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  3,597 results for ""SYMPTOMATIC Parkinson's disease""