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Metformin as a Potential In Vitro Anticancer Modulator of Adenosine Monophosphate Kinase: A Review

• Authors : Jinadasa, A. G. R. Greshamali; Akalanka, H. M. Kasuni; Wageesha, N. D. Amal

• Source: International Journal of Breast Cancer. August 27, 2024, Vol. 2024

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Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/ endothelial nitric oxide synthase pathway.

• Authors : Jin-Yun Zhao; Xiao-Long Sheng; Cheng-Jun Li

• Source: Neural Regeneration Research; Jul2023, Vol. 18 Issue 7, p1553-1562, 19p

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Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration.

• Authors : Zhang L; NMR Laboratory for Physiological Chemistry, Divivion of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.; He H

Subjects: Adenosine Monophosphate/Adenosine Monophosphate/Adenosine Monophosphate/*metabolism ; Adenylate Kinase/Adenylate Kinase/Adenylate Kinase/*metabolism ; Cytosol/Cytosol/Cytosol/*metabolism

• Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2007 Jul; Vol. 293 (1), pp. H457-66. Date of Electronic Publication: 2007 Mar 16.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium:

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The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism.

• Authors : Hawley SA; Division of Molecular Physiology, School of Life Sciences and Wellcome Trust Biocentre, Dundee University, Dundee, Scotland, UK.; Gadalla AE

Subjects: Adenosine Monophosphate/Adenosine Monophosphate/Adenosine Monophosphate/*metabolism ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacology ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*physiology

• Source: Diabetes [Diabetes] 2002 Aug; Vol. 51 (8), pp. 2420-5.Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Print ISSN:

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Synthesis, Characterisation and Cytotoxic Studies of Novel Curcumin-Metformin Conjugate.

• Authors : Perumalsamy, Vijaybhanu¹ ; D. R., Harish Kumar¹; Suresh, Sarasija²

Subjects: *ADENOSINE monophosphate; *SUCCINIC anhydride; *TURMERIC

• Source: Journal of Young Pharmacists. Jan-Mar2022, Vol. 14 Issue 1, p73-76. 4p.

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Study Findings from Department of Basic Sciences Advance Knowledge in Anticancer Agents (Metformin as a Potential In Vitro Anticancer Modulator of Adenosine Monophosphate Kinase: A Review).

Subjects: HYPOGLYCEMIC agents; CARDIOVASCULAR agents; ADENOSINE monophosphate

• Source: Drug Week; 9/27/2024, p911-911, 1p

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Targeting Adenosine Monophosphate-Activated Protein Kinase by Metformin Adjusts Post-Ischemic Hyperemia and Extracellular Neuronal Discharge in Transient Global Cerebral Ischemia.

• Authors : Farbood, Yaghoob^1,2; Sarkaki, Alireza^1,2; Khalaj, Leila³

Subjects: *CEREBRAL ischemia; *ADENOSINE monophosphate; *PROTEIN kinases

• Source: Microcirculation. Oct2015, Vol. 22 Issue 7, p534-541. 8p.

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Metformin Prevents Cocaine Sensitization: Involvement of Adenosine Monophosphate-Activated Protein Kinase Trafficking between Subcellular Compartments in the Corticostriatal Reward Circuit.

• Authors : Aruldas, Rachel; Orenstein, Laura Buczek; Spencer, Sade

Subjects: PROTEIN kinases; COCAINE-induced disorders; AMP-activated protein kinases

• Source: International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 23, p16859, 21p

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Role of adenosine monophosphate-activated protein kinase on cell migration, matrix contraction, and matrix metalloproteinase-1 and matrix metalloproteinase-2 production in nasal polyp-derived fibroblasts.

• Authors : Ji-Young Um; Seoung-Ae Lee; Joo-Hoo Park

Subjects: PROTEIN kinases; METFORMIN; CELL migration

• Source: American Journal of Rhinology & Allergy; Nov/Dec2017, Vol. 31 Issue 6, p357-363, 7p

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Reports from Medical University of Silesia Describe Recent Advances in Cardiac Stressing Agents [Erratum to 'Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial ...]

• Source: Obesity, Fitness & Wellness Week. February 15, 2020, 5109

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