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Academic Journal

Antibody targeting of E3 ubiquitin ligases for receptor degradation.

  • Authors : Marei H; Discovery Oncology, Genentech, South San Francisco, CA, USA.; Tsai WK

Subjects: Antibodies*/Antibodies*/Antibodies*/immunology ; Antibodies*/Antibodies*/Antibodies*/metabolism ; Antibody Specificity*

  • Source: Nature [Nature] 2022 Oct; Vol. 610 (7930), pp. 182-189. Date of Electronic Publication: 2022 Sep 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation.

  • Authors : Zeng LW; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University; Medical Research Institute

Subjects: Asthma* ; Eosinophilia*; Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/*metabolism

  • Source: Cellular & molecular immunology [Cell Mol Immunol] 2022 Oct; Vol. 19 (10), pp. 1117-1129. Date of Electronic Publication: 2022 Aug 19.Publisher: Chinese Society of Immunology;; _b Nature Pub. Group Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited

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Academic Journal

Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases.

  • Authors : Jiang H; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115.; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205.

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*genetics ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*genetics ; Nedd4 Ubiquitin Protein Ligases/Nedd4 Ubiquitin Protein Ligases/Nedd4 Ubiquitin Protein Ligases/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Nov 15; Vol. 294 (46), pp. 17421-17436. Date of Electronic Publication: 2019 Oct 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.

  • Authors : Lu G; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore , Singapore.; Yi J

Subjects: Autophagy/Autophagy/Autophagy/*genetics ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Mitosis/Mitosis/Mitosis/*genetics

  • Source: Autophagy [Autophagy] 2019 Nov; Vol. 15 (11), pp. 1917-1934. Date of Electronic Publication: 2019 Mar 30.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Angiomotin-Like 1 Links Paramyxovirus M Proteins to NEDD4 Family Ubiquitin Ligases.

  • Authors : Ray G; Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA. .; Schmitt PT

Subjects: Virus Release*; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Nedd4 Ubiquitin Protein Ligases/Nedd4 Ubiquitin Protein Ligases/Nedd4 Ubiquitin Protein Ligases/*metabolism

  • Source: Viruses [Viruses] 2019 Jan 31; Vol. 11 (2). Date of Electronic Publication: 2019 Jan 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation.

  • Authors : Zattas D; From the Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520 and.; Berk JM

Subjects: Endoplasmic Reticulum-Associated Degradation*; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Saccharomyces cerevisiae Proteins/Saccharomyces cerevisiae Proteins/Saccharomyces cerevisiae Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Jun 03; Vol. 291 (23), pp. 12105-18. Date of Electronic Publication: 2016 Apr 11.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke.

  • Authors : Lackovic J; Brain Development and Regeneration Laboratory, Florey Neuroscience Institutes, The University of Melbourne, Parkville, Australia.; Howitt J

Subjects: Brain Ischemia/Brain Ischemia/Brain Ischemia/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*metabolism

  • Source: Experimental neurology [Exp Neurol] 2012 May; Vol. 235 (1), pp. 326-35. Date of Electronic Publication: 2012 Mar 05.Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Origin and diversification of TRIM ubiquitin ligases.

  • Authors : Marín I; Instituto de Biomedicina de Valencia (IBV-CSIC), Consejo Superior de Investigaciones Científicas, Valencia, Spain.

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/chemistry ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/classification ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics

  • Source: PloS one [PLoS One] 2012; Vol. 7 (11), pp. e50030. Date of Electronic Publication: 2012 Nov 21.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.

Subjects: Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/*metabolism ; Guanylate Kinases/Guanylate Kinases/Guanylate Kinases/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: Developmental cell [Dev Cell] 2011 Sep 13; Vol. 21 (3), pp. 479-91.Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print Cited Medium: Internet ISSN: 1878-1551

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Academic Journal

Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD.

  • Authors : Stolz A; Institut für Biochemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany.; Schweizer RS

Subjects: Adenosine Triphosphatases/Adenosine Triphosphatases/Adenosine Triphosphatases/*metabolism ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*metabolism

  • Source: Traffic (Copenhagen, Denmark) [Traffic] 2010 Oct; Vol. 11 (10), pp. 1363-9.Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print Cited Medium: Internet ISSN: 1600-0854 (Electronic)

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  • 1-10 of  38 results for ""UBIQUITIN ligases""