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Academic Journal

Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis.

  • Authors : Wettstadt S; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín-Consejo Superior de Investigaciones Científicas, Granada, Spain.; Marcos-Torres FJ

Subjects: Proteolysis* ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/metabolism ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/genetics

  • Source: PLoS biology [PLoS Biol] 2024 Dec 02; Vol. 22 (12), pp. e3002920. Date of Electronic Publication: 2024 Dec 02 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons.

  • Authors : Zlamalova E; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK; Department of Medical Genetics, University of Cambridge, Cambridge, UK.

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Neurons*/Neurons*/Neurons*/metabolism ; Neurons*/Neurons*/Neurons*/pathology

  • Source: Neurobiology of disease [Neurobiol Dis] 2024 Sep; Vol. 199, pp. 106556. Date of Electronic Publication: 2024 Jun 06.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control.

  • Authors : Ero R; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, 636921 Singapore.

Subjects: Proteolysis* ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/chemistry

  • Source: Biochemical Society transactions [Biochem Soc Trans] 2024 Oct 30; Vol. 52 (5), pp. 2077-2086.Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium:

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Academic Journal

The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi.

  • Authors : Weyer Y; Institute of Molecular Biochemistry, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.; Institute of Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.

Subjects: Golgi Apparatus*/Golgi Apparatus*/Golgi Apparatus*/metabolism ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/metabolism ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/genetics

  • Source: Nature communications [Nat Commun] 2024 Oct 26; Vol. 15 (1), pp. 9257. Date of Electronic Publication: 2024 Oct 26.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCF FBXL4 .

  • Authors : Nguyen-Dien GT; Faculty of Medicine, School of Biomedical Sciences, University of Queensland, Brisbane, QLD, Australia.; Department of Biotechnology, School of Biotechnology, Viet Nam National University-International University, Ho Chi Minh City, Vietnam.

Subjects: F-Box Proteins*/F-Box Proteins*/F-Box Proteins*/metabolism ; F-Box Proteins*/F-Box Proteins*/F-Box Proteins*/genetics ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: EMBO reports [EMBO Rep] 2024 Aug; Vol. 25 (8), pp. 3324-3347. Date of Electronic Publication: 2024 Jul 11.Publisher: Wiley Blackwell Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Small molecule induced STING degradation facilitated by the HECT ligase HERC4.

  • Authors : Mutlu M; Novartis BioMedical Research, Basel, Switzerland. .; Schmidt I

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: Nature communications [Nat Commun] 2024 May 29; Vol. 15 (1), pp. 4584. Date of Electronic Publication: 2024 May 29.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass.

  • Authors : Sun Y; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China; National Institute of Biological Sciences, Beijing 102206, China

Subjects: Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism ; Mitochondrial Membranes*/Mitochondrial Membranes*/Mitochondrial Membranes*/metabolism ; Mitochondrial Proteins*/Mitochondrial Proteins*/Mitochondrial Proteins*/metabolism

  • Source: Molecular cell [Mol Cell] 2024 Jan 18; Vol. 84 (2), pp. 327-344.e9. Date of Electronic Publication: 2023 Dec 26.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras.

  • Authors : Ahn G; Department of Chemistry, Stanford University, Stanford, CA 94305, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA.

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism ; Proteolysis*

  • Source: Science (New York, N.Y.) [Science] 2023 Oct 20; Vol. 382 (6668), pp. eadf6249. Date of Electronic Publication: 2023 Oct 20.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Targeted degradation of extracellular secreted and membrane proteins.

  • Authors : Chen X; Lachman Institute for Pharmaceutical Development, School of Pharmacy, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705, USA.; Zhou Y

Subjects: Proteolysis* ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism; Humans

  • Source: Trends in pharmacological sciences [Trends Pharmacol Sci] 2023 Nov; Vol. 44 (11), pp. 762-775. Date of Electronic Publication: 2023 Sep 25.Publisher: Published By Elsevier In Association With The International Union Of Pharmacology Country of Publication: England NLM ID: 7906158 Publication Model:

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Academic Journal

Antibody targeting of E3 ubiquitin ligases for receptor degradation.

  • Authors : Marei H; Discovery Oncology, Genentech, South San Francisco, CA, USA.; Tsai WK

Subjects: Antibodies*/Antibodies*/Antibodies*/immunology ; Antibodies*/Antibodies*/Antibodies*/metabolism ; Antibody Specificity*

  • Source: Nature [Nature] 2022 Oct; Vol. 610 (7930), pp. 182-189. Date of Electronic Publication: 2022 Sep 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  6,080 results for ""Proteolysis""