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Academic Journal

Apolipoprotein E deficiency leads to the polarization of splenic macrophages towards M1 phenotype by increasing iron content.

  • Authors : Shen MQ; Institute of Translational and Precision Medicine, Nantong University, Nantong, Jiangsu, China.; School of Health Medicine, Nantong Polytechnic College, Nantong, China.

Subjects: Iron*/Iron*/Iron*/metabolism ; Spleen*/Spleen*/Spleen*/metabolism ; Spleen*/Spleen*/Spleen*/cytology

  • Source: Genes and immunity [Genes Immun] 2024 Oct; Vol. 25 (5), pp. 381-388. Date of Electronic Publication: 2024 Aug 05.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.

  • Authors : Chen L; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.; The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China.

Subjects: Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/metabolism ; Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/genetics ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism

  • Source: Theranostics [Theranostics] 2024 Jul 08; Vol. 14 (11), pp. 4256-4277. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Anti-atherosclerotic effect of tetrahydroxy stilbene glucoside via dual-targeting of hepatic lipid metabolisms and aortic M2 macrophage polarization in ApoE -/- mice.

  • Authors : Li M; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.; Meng Y

Subjects: Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/drug therapy ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism ; Glucosides*/Glucosides*/Glucosides*/pharmacology

  • Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Sep 15; Vol. 248, pp. 116338. Date of Electronic Publication: 2024 Jul 03.Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

APOE expression in papillary thyroid carcinoma: Influencing tumor progression and macrophage polarization.

  • Authors : Huo R; Department of Morphology Laboratory, Hebei North University, Zhangjiakou 075000, China.; Zhao R

Subjects: Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/pathology ; Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/immunology ; Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/Thyroid Cancer, Papillary*/metabolism

  • Source: Immunobiology [Immunobiology] 2024 Sep; Vol. 229 (5), pp. 152821. Date of Electronic Publication: 2024 Jun 06.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8002742 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pan-Cancer Single-Cell and Spatial-Resolved Profiling Reveals the Immunosuppressive Role of APOE+ Macrophages in Immune Checkpoint Inhibitor Therapy.

  • Authors : Liu C; Department of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China.; Xie J

Subjects: Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/pharmacology ; Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/therapeutic use ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jun; Vol. 11 (23), pp. e2401061. Date of Electronic Publication: 2024 Apr 03.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

LXR Agonist T0901317's Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout Mice.

  • Authors : Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.

Subjects: Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/deficiency ; Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/genetics ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/drug therapy

  • Source: Biomolecules [Biomolecules] 2024 Apr 02; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury.

  • Authors : Yao XQ; Division of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Chen JY

Subjects: Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/genetics ; Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/immunology ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: Frontiers in immunology [Front Immunol] 2022 Aug 24; Vol. 13, pp. 964138. Date of Electronic Publication: 2022 Aug 24 (Print Publication: 2022).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis.

  • Authors : Park I; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.; Goddard ME

Subjects: Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*genetics ; Atherosclerosis/Atherosclerosis/Atherosclerosis/*genetics ; Blood Vessels/Blood Vessels/Blood Vessels/*metabolism

  • Source: Nature communications [Nat Commun] 2022 Jan 11; Vol. 13 (1), pp. 215. Date of Electronic Publication: 2022 Jan 11.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE -/- mice atherosclerosis.

  • Authors : Xu L; Department of Pathophysiology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, China.; National Health Commission Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, China.

Subjects: Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*genetics ; Atherosclerosis/Atherosclerosis/Atherosclerosis/*genetics ; Homocysteine/Homocysteine/Homocysteine/*pharmacology

  • Source: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2022 Jan; Vol. 102 (1), pp. 25-37. Date of Electronic Publication: 2021 Nov 01.Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Adaptive Immune Response Signaling Is Suppressed in Ly6C high Monocyte but Upregulated in Monocyte Subsets of ApoE -/- Mice - Functional Implication in Atherosclerosis.

  • Authors : Yang P; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Center for Metabolic Disease Research, Department of Cardiovascular Science, Lewis Kats School of Medicine, Temple University, Philadelphia, PA, United States.

Subjects: Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*metabolism ; Atherosclerosis/Atherosclerosis/Atherosclerosis/*immunology ; Inflammation/Inflammation/Inflammation/*immunology

  • Source: Frontiers in immunology [Front Immunol] 2021 Dec 20; Vol. 12, pp. 809208. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 of  1,321 results for ""Apolipoproteins E""