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Academic Journal

MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2D Low T cells.

  • Authors : Toyoda H; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, 6-11-11 Kita-karasuyama, Setagaya-ku, Tokyo, 157-8577, Japan.; Department of Pharmacology, Showa University School of Medicine, Tokyo, 142-8555, Japan.

Subjects: NK Cell Lectin-Like Receptor Subfamily K*/NK Cell Lectin-Like Receptor Subfamily K*/NK Cell Lectin-Like Receptor Subfamily K*/metabolism ; NK Cell Lectin-Like Receptor Subfamily K*/NK Cell Lectin-Like Receptor Subfamily K*/NK Cell Lectin-Like Receptor Subfamily K*/genetics ; Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 08; Vol. 14 (1), pp. 23401. Date of Electronic Publication: 2024 Oct 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation.

  • Authors : Kulicke CA; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health & Science University, Portland, OR, 97239, USA.; Swarbrick GM

Subjects: Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/metabolism ; Lymphocyte Activation*; Ribitol/Ribitol/Ribitol/*analogs & derivatives

  • Source: Communications biology [Commun Biol] 2024 Feb 24; Vol. 7 (1), pp. 228. Date of Electronic Publication: 2024 Feb 24.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs.

  • Authors : Knezevic L; Faculty of Health Sciences, University of Bristol, Bristol, UK; Department of Haematology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: .

Subjects: CD8 Antigens* ; CD8-Positive T-Lymphocytes* ; Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/Histocompatibility Antigens Class I*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Aug; Vol. 299 (8), pp. 104981. Date of Electronic Publication: 2023 Jun 28.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck.

  • Authors : Zhao X; Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Subjects: CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology ; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*metabolism ; Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*immunology

  • Source: Frontiers in immunology [Front Immunol] 2021 Oct 11; Vol. 12, pp. 721722. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response.

  • Authors : Ruf B; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.; Catania VV

Subjects: Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*metabolism ; Lymphocyte Activation/Lymphocyte Activation/Lymphocyte Activation/*immunology ; Minor Histocompatibility Antigens/Minor Histocompatibility Antigens/Minor Histocompatibility Antigens/*metabolism

  • Source: Cancer immunology research [Cancer Immunol Res] 2021 Sep; Vol. 9 (9), pp. 1024-1034. Date of Electronic Publication: 2021 Jun 30.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited

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Academic Journal

Proteolysis-Targeting Chimeras Enhance T Cell Bispecific Antibody-Driven T Cell Activation and Effector Function through Increased MHC Class I Antigen Presentation in Cancer Cells.

  • Authors : Massafra V; Molecular Targeted Therapy-Discovery Oncology, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.; Tundo S

Subjects: Antibodies, Bispecific/Antibodies, Bispecific/Antibodies, Bispecific/*immunology ; Antigen Presentation/Antigen Presentation/Antigen Presentation/*immunology ; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology

  • Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Jul 15; Vol. 207 (2), pp. 493-504. Date of Electronic Publication: 2021 Jul 02.Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlation With Natural Killer Cell Activity in Systemic Lupus Erythematosus.

  • Authors : Hervier B; INSERM U1135, CNRS ERL 8255, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, Paris, France.; Service de Médecine Interne-Maladies Systémiques, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, Paris, France.

Subjects: Lymphocyte Activation*; Cell Membrane/Cell Membrane/Cell Membrane/*immunology ; Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*blood

  • Source: Frontiers in immunology [Front Immunol] 2021 May 03; Vol. 12, pp. 633658. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing.

  • Authors : Seidel E; The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel.; Dassa L

Subjects: Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*immunology ; Cytomegalovirus Infections/Cytomegalovirus Infections/Cytomegalovirus Infections/*immunology ; Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2021 May 03; Vol. 17 (5), pp. e1008807. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity.

  • Authors : Shahine A; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.

Subjects: Lymphocyte Activation*; Antigens/Antigens/Antigens/*immunology ; Antigens, CD1/Antigens, CD1/Antigens, CD1/*immunology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

SARS-CoV-2 Spike 1 Protein Controls Natural Killer Cell Activation via the HLA-E/NKG2A Pathway.

  • Authors : Bortolotti D; Department of Chemical and Pharmaceutical Science, University of Ferrara, 44121 Ferrara, Italy.; Gentili V

Subjects: Betacoronavirus/Betacoronavirus/Betacoronavirus/*chemistry ; Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*immunology ; Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/Histocompatibility Antigens Class I/*metabolism

  • Source: Cells [Cells] 2020 Aug 26; Vol. 9 (9). Date of Electronic Publication: 2020 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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  • 1-10 of  263 results for ""HISTOCOMPATIBILITY class I antigens""